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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 331 to 340 of 348

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E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis.
Nip J, Strom DK, Fee BE, Zambetti G, Cleveland JL, Hiebert SW
(1997) Mol Cell Biol 17: 1049-56
MeSH Terms: Antineoplastic Agents, Apoptosis, Bone Marrow Cells, Carrier Proteins, Cell Cycle, Cell Cycle Proteins, Cell Survival, DNA Damage, DNA-Binding Proteins, Diketopiperazines, Doxorubicin, E2F Transcription Factors, E2F1 Transcription Factor, Enzyme Inhibitors, Etoposide, Fluorouracil, Gamma Rays, Gene Expression, Humans, Piperazines, Proto-Oncogene Proteins c-bcl-2, Retinoblastoma-Binding Protein 1, Topoisomerase II Inhibitors, Transcription Factor DP1, Transcription Factors, Tumor Suppressor Protein p53
Added June 10, 2010
1 Communities
1 Members
0 Resources
26 MeSH Terms
Characterization of novel mutations at the Schizosaccharomyces pombe cdc2 regulatory phosphorylation site, tyrosine 15.
Gould KL, Feoktistova A
(1996) Mol Biol Cell 7: 1573-86
MeSH Terms: CDC2 Protein Kinase, Cell Cycle, Cell Cycle Proteins, Fungal Proteins, Genetic Complementation Test, Microtubules, Mutagenesis, Site-Directed, Nuclear Proteins, Phosphorylation, Phosphotyrosine, Protein Kinases, Protein Processing, Post-Translational, Protein-Tyrosine Kinases, Recombinant Fusion Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Tyrosine
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Indirect and direct disruption of transcriptional regulation in cancer: E2F and AML-1.
Meyers S, Hiebert SW
(1995) Crit Rev Eukaryot Gene Expr 5: 365-83
MeSH Terms: Carrier Proteins, Cell Cycle Proteins, Core Binding Factor Alpha 2 Subunit, DNA-Binding Proteins, E2F Transcription Factors, Gene Expression Regulation, Neoplastic, Humans, Neoplasms, Proto-Oncogene Proteins, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors, Transcription, Genetic
Added June 10, 2010
1 Communities
1 Members
0 Resources
13 MeSH Terms
Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant.
Plyte SE, Feoktistova A, Burke JD, Woodgett JR, Gould KL
(1996) Mol Cell Biol 16: 179-91
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Calcium-Calmodulin-Dependent Protein Kinases, Cell Cycle Proteins, Cell Division, Cloning, Molecular, DNA, Complementary, DNA, Fungal, Fungal Proteins, Gene Deletion, Genes, Fungal, Genetic Complementation Test, Glycogen Synthase Kinase 3, Glycogen Synthase Kinases, Humans, Molecular Sequence Data, Mutation, Phosphorylation, Protein Tyrosine Phosphatases, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Sequence Homology, Amino Acid
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis.
Hiebert SW, Packham G, Strom DK, Haffner R, Oren M, Zambetti G, Cleveland JL
(1995) Mol Cell Biol 15: 6864-74
MeSH Terms: Animals, Apoptosis, Carrier Proteins, Cell Cycle Proteins, Cell Line, DNA Damage, DNA-Binding Proteins, Dexamethasone, E2F Transcription Factors, E2F1 Transcription Factor, Fibroblasts, Gene Expression, Humans, Interleukin-3, Kinetics, Recombinant Proteins, Retinoblastoma-Binding Protein 1, Time Factors, Transcription Factor DP1, Transcription Factors, Transfection, Tumor Suppressor Protein p53
Added June 10, 2010
1 Communities
1 Members
0 Resources
22 MeSH Terms
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression.
Hiebert SW
(1993) Mol Cell Biol 13: 3384-91
MeSH Terms: Adenovirus E1A Proteins, Adenovirus E2 Proteins, Binding Sites, Carrier Proteins, Cell Cycle, Cell Cycle Proteins, Cell Division, DNA-Binding Proteins, E2F Transcription Factors, Female, G1 Phase, Genes, Retinoblastoma, Humans, Promoter Regions, Genetic, Retinoblastoma Protein, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors, Transfection, Tumor Cells, Cultured, Uterine Cervical Neoplasms
Added June 10, 2010
1 Communities
1 Members
0 Resources
21 MeSH Terms
The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb.
Ohi R, McCollum D, Hirani B, Den Haese GJ, Zhang X, Burke JD, Turner K, Gould KL
(1994) EMBO J 13: 471-83
MeSH Terms: Amino Acid Sequence, Base Sequence, Cell Cycle Proteins, Cloning, Molecular, DNA Replication, DNA, Fungal, DNA-Binding Proteins, Fungal Proteins, Genes, Fungal, Genetic Complementation Test, Hydroxyurea, Molecular Sequence Data, Phenotype, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-myb, Restriction Mapping, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Sequence Homology, Amino Acid
Added March 5, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1.
Roussel MF, Davis JN, Cleveland JL, Ghysdael J, Hiebert SW
(1994) Oncogene 9: 405-15
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Carrier Proteins, Cell Cycle Proteins, Cell Line, DNA, DNA-Binding Proteins, E2F Transcription Factors, E2F1 Transcription Factor, Electrophoresis, Fibroblasts, Gene Expression Regulation, Genes, myc, Mice, Molecular Sequence Data, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Protein c-ets-1, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-ets, Proto-Oncogene Proteins c-myc, Retinoblastoma-Binding Protein 1, S Phase, Transcription Factor DP1, Transcription Factors, Transcription, Genetic, Transcriptional Activation, Transfection
Added June 10, 2010
1 Communities
1 Members
0 Resources
29 MeSH Terms
The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis.
Balasubramanian MK, Hirani BR, Burke JD, Gould KL
(1994) J Cell Biol 125: 1289-301
MeSH Terms: Actins, Amino Acid Sequence, Base Sequence, Cell Cycle Proteins, Cell Division, Cell Nucleus, Cloning, Molecular, Contractile Proteins, Fluorescent Antibody Technique, Fungal Proteins, Genes, Fungal, Microfilament Proteins, Molecular Sequence Data, Mutation, Profilins, Recombinant Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Sequence Analysis, DNA, Sequence Homology, Amino Acid
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
An E2F dominant negative mutant blocks E1A induced cell cycle progression.
Dobrowolski SF, Stacey DW, Harter ML, Stine JT, Hiebert SW
(1994) Oncogene 9: 2605-12
MeSH Terms: 3T3 Cells, Adenovirus E1A Proteins, Animals, Carrier Proteins, Cell Cycle, Cell Cycle Proteins, DNA, DNA-Binding Proteins, E2F Transcription Factors, E2F1 Transcription Factor, Genes, myc, Glutathione Transferase, HeLa Cells, Humans, Mice, Mutation, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors
Added June 10, 2010
1 Communities
1 Members
0 Resources
19 MeSH Terms