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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 77

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Glucose decouples intracellular Ca2+ activity from glucagon secretion in mouse pancreatic islet alpha-cells.
Le Marchand SJ, Piston DW
(2012) PLoS One 7: e47084
MeSH Terms: Animals, Arginine, Calcium, Calcium Signaling, Glucagon, Glucagon-Secreting Cells, Glucose, Mice, Mice, Inbred C57BL, Mice, Transgenic, Potassium Channels, Sodium Channel Blockers, Sodium Channels, Tetrodotoxin
Added December 5, 2013
3 Communities
1 Members
0 Resources
14 MeSH Terms
Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Yang T, Atack TC, Stroud DM, Zhang W, Hall L, Roden DM
(2012) Circ Res 111: 322-32
MeSH Terms: Action Potentials, Aniline Compounds, Animals, Anti-Arrhythmia Agents, Arrhythmias, Cardiac, Cell Line, Transformed, Furans, Humans, Mice, Mice, Knockout, NAV1.5 Voltage-Gated Sodium Channel, NAV1.8 Voltage-Gated Sodium Channel, Rabbits, Rats, Sodium Channel Blockers, Sodium Channels
Added June 26, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.
Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM
(2012) J Neurosci 32: 5716-27
MeSH Terms: Analysis of Variance, Animals, Bacterial Proteins, Biophysics, Biotinylation, Cell Line, Transformed, Cerebral Cortex, Cycloheximide, Electric Stimulation, Endocytosis, Gene Expression Regulation, Green Fluorescent Proteins, Humans, Immunoprecipitation, Luminescent Proteins, Mass Spectrometry, Mice, Mice, Inbred C57BL, Mice, Knockout, Neurons, Patch-Clamp Techniques, Protein Synthesis Inhibitors, Proteomics, RNA, Small Interfering, Receptors, Transferrin, Shal Potassium Channels, Sodium Channels, Transfection, Voltage-Gated Sodium Channel beta-1 Subunit
Added February 20, 2015
0 Communities
1 Members
0 Resources
29 MeSH Terms
Confirmation of an epilepsy modifier locus on mouse chromosome 11 and candidate gene analysis by RNA-Seq.
Hawkins NA, Kearney JA
(2012) Genes Brain Behav 11: 452-60
MeSH Terms: Alleles, Animals, Chromosomes, Mammalian, Epilepsy, Genes, Modifier, Genotype, Male, Mice, Mutation, NAV1.2 Voltage-Gated Sodium Channel, Nerve Tissue Proteins, Sodium Channels, Transcriptome
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Activation of protein kinase C alters the intracellular distribution and mobility of cardiac Na+ channels.
Hallaq H, Wang DW, Kunic JD, George AL, Wells KS, Murray KT
(2012) Am J Physiol Heart Circ Physiol 302: H782-9
MeSH Terms: Calcium, Cell Membrane, Cyclic AMP-Dependent Protein Kinases, Enzyme Activation, Green Fluorescent Proteins, HEK293 Cells, Humans, Membrane Potentials, Myocardial Contraction, Myocardium, NAV1.5 Voltage-Gated Sodium Channel, Protein Kinase C, Protein Transport, Sodium Channels
Added December 5, 2013
2 Communities
2 Members
0 Resources
14 MeSH Terms
Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Watanabe H, Yang T, Stroud DM, Lowe JS, Harris L, Atack TC, Wang DW, Hipkens SB, Leake B, Hall L, Kupershmidt S, Chopra N, Magnuson MA, Tanabe N, Knollmann BC, George AL, Roden DM
(2011) Circulation 124: 1001-11
MeSH Terms: Animals, Atrial Flutter, CHO Cells, Cardiomyopathy, Dilated, Cricetinae, Cricetulus, Defibrillators, Implantable, Electrocardiography, Humans, Male, Mice, Mice, Transgenic, Mutation, Missense, Myocardial Contraction, NAV1.5 Voltage-Gated Sodium Channel, Sick Sinus Syndrome, Sodium Channels, Treatment Outcome, Young Adult
Added December 5, 2013
4 Communities
5 Members
0 Resources
19 MeSH Terms
Informatic and functional approaches to identifying a regulatory region for the cardiac sodium channel.
Atack TC, Stroud DM, Watanabe H, Yang T, Hall L, Hipkens SB, Lowe JS, Leake B, Magnuson MA, Yang P, Roden DM
(2011) Circ Res 109: 38-46
MeSH Terms: Animals, Base Sequence, CHO Cells, Conserved Sequence, Cricetinae, Cricetulus, Electrocardiography, Gene Expression Regulation, Humans, Mice, Molecular Sequence Data, NAV1.5 Voltage-Gated Sodium Channel, Promoter Regions, Genetic, Regulatory Sequences, Nucleic Acid, Sodium Channels, Transcription, Genetic
Added January 10, 2014
2 Communities
5 Members
0 Resources
16 MeSH Terms
Protective effects of PPARγ agonist in acute nephrotic syndrome.
Zuo Y, Yang HC, Potthoff SA, Najafian B, Kon V, Ma LJ, Fogo AB
(2012) Nephrol Dial Transplant 27: 174-81
MeSH Terms: Actinin, Acute Disease, Animals, Antibiotics, Antineoplastic, Aquaporin 2, Blotting, Western, Cells, Cultured, Desmin, Epithelial Sodium Channels, Hypoglycemic Agents, Immunoenzyme Techniques, Male, Nephrotic Syndrome, PPAR gamma, Pioglitazone, Podocytes, Proteinuria, Puromycin Aminonucleoside, Rats, Rats, Sprague-Dawley, Thiazolidinediones, Water-Electrolyte Balance
Added January 24, 2012
2 Communities
2 Members
0 Resources
22 MeSH Terms
SCN5A variation is associated with electrocardiographic traits in the Jackson Heart Study.
Jeff JM, Brown-Gentry K, Buxbaum SG, Sarpong DF, Taylor HA, George AL, Roden DM, Crawford DC
(2011) Circ Cardiovasc Genet 4: 139-44
MeSH Terms: Adult, Aged, Aged, 80 and over, Arrhythmias, Cardiac, Electrocardiography, Female, Genotype, Heart Rate, Humans, Longitudinal Studies, Male, Middle Aged, Myocardium, NAV1.5 Voltage-Gated Sodium Channel, Polymorphism, Single Nucleotide, Risk Factors, Sodium Channels
Added June 26, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Relating form and function of EF-hand calcium binding proteins.
Chazin WJ
(2011) Acc Chem Res 44: 171-9
MeSH Terms: Amino Acid Motifs, Animals, Binding Sites, Calbindins, Calcium, Calcium-Binding Proteins, Calmodulin, Chromosomal Proteins, Non-Histone, EF Hand Motifs, Humans, Magnetic Resonance Spectroscopy, Models, Molecular, NAV1.5 Voltage-Gated Sodium Channel, Protein Binding, Protein Conformation, Protein Structure, Tertiary, S100 Calcium Binding Protein G, Signal Transduction, Sodium Channels, Structure-Activity Relationship, Thermodynamics, Vertebrates
Added March 7, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms