Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 21 to 27 of 27

Publication Record

Connections

Role of transforming growth factor-beta signaling in cancer.
de Caestecker MP, Piek E, Roberts AB
(2000) J Natl Cancer Inst 92: 1388-402
MeSH Terms: Animals, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Humans, Mutation, Neoplasms, Receptors, Transforming Growth Factor beta, Signal Transduction, Smad2 Protein, Smad3 Protein, Smad4 Protein, Trans-Activators, Transforming Growth Factor beta
Added January 5, 2011
2 Communities
1 Members
0 Resources
14 MeSH Terms
The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors.
Yahata T, de Caestecker MP, Lechleider RJ, Andriole S, Roberts AB, Isselbacher KJ, Shioda T
(2000) J Biol Chem 275: 8825-34
MeSH Terms: Amino Acid Sequence, Animals, Apoptosis Regulatory Proteins, Binding Sites, Carrier Proteins, DNA-Binding Proteins, HSC70 Heat-Shock Proteins, HSP70 Heat-Shock Proteins, Humans, Models, Genetic, Molecular Sequence Data, Multigene Family, Nuclear Proteins, Protein Binding, Protein Structure, Tertiary, Sequence Homology, Amino Acid, Smad4 Protein, Trans-Activators, Transcription Factors, Transcription, Genetic
Added January 5, 2011
2 Communities
1 Members
0 Resources
20 MeSH Terms
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain.
de Caestecker MP, Yahata T, Wang D, Parks WT, Huang S, Hill CS, Shioda T, Roberts AB, Lechleider RJ
(2000) J Biol Chem 275: 2115-22
MeSH Terms: Amino Acid Sequence, Animals, COS Cells, Cell Line, Cytoplasm, DNA-Binding Proteins, E1A-Associated p300 Protein, Fluorescent Antibody Technique, Humans, Mice, Molecular Sequence Data, Nuclear Proteins, Precipitin Tests, Proline, Protein Binding, Protein Structure, Tertiary, Smad2 Protein, Smad4 Protein, Trans-Activators, Transcription, Genetic, Transcriptional Activation
Added January 5, 2011
2 Communities
1 Members
0 Resources
21 MeSH Terms
The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
Poncelet AC, de Caestecker MP, Schnaper HW
(1999) Kidney Int 56: 1354-65
MeSH Terms: Blotting, Northern, Blotting, Western, Cells, Cultured, Collagen, DNA-Binding Proteins, Extracellular Matrix Proteins, Gene Expression Regulation, Genes, Reporter, Glomerular Mesangium, Humans, Luciferases, Mutagenesis, Phosphorylation, Promoter Regions, Genetic, RNA, Messenger, Serine, Signal Transduction, Smad2 Protein, Smad3 Protein, Smad4 Protein, Trans-Activators, Transcription, Genetic, Transfection, Transforming Growth Factor beta
Added January 5, 2011
2 Communities
1 Members
0 Resources
24 MeSH Terms
SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.
Vindevoghel L, Lechleider RJ, Kon A, de Caestecker MP, Uitto J, Roberts AB, Mauviel A
(1998) Proc Natl Acad Sci U S A 95: 14769-74
MeSH Terms: Animals, COS Cells, Collagen, DNA-Binding Proteins, Female, Humans, Lymphotoxin-alpha, Promoter Regions, Genetic, Signal Transduction, Smad3 Protein, Smad4 Protein, Trans-Activators, Transcriptional Activation, Tumor Cells, Cultured
Added January 5, 2011
2 Communities
1 Members
0 Resources
14 MeSH Terms
Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator.
Shioda T, Lechleider RJ, Dunwoodie SL, Li H, Yahata T, de Caestecker MP, Fenner MH, Roberts AB, Isselbacher KJ
(1998) Proc Natl Acad Sci U S A 95: 9785-90
MeSH Terms: 3T3 Cells, Animals, Apoptosis Regulatory Proteins, Binding Sites, DNA-Binding Proteins, Humans, In Vitro Techniques, Mice, Mutation, Nuclear Proteins, Protein Conformation, Recombinant Fusion Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Signal Transduction, Smad4 Protein, Trans-Activators, Transcription Factors, Transcriptional Activation, Transfection, Transforming Growth Factor beta
Added January 5, 2011
2 Communities
1 Members
0 Resources
21 MeSH Terms
Characterization of functional domains within Smad4/DPC4.
de Caestecker MP, Hemmati P, Larisch-Bloch S, Ajmera R, Roberts AB, Lechleider RJ
(1997) J Biol Chem 272: 13690-6
MeSH Terms: Binding Sites, Cell Line, DNA-Binding Proteins, Genes, Tumor Suppressor, Humans, Ligands, Peptide Mapping, RNA, Messenger, Recombinant Fusion Proteins, Signal Transduction, Smad Proteins, Smad1 Protein, Smad4 Protein, Trans-Activators, Transforming Growth Factor beta, Tumor Cells, Cultured
Added January 5, 2011
2 Communities
1 Members
0 Resources
16 MeSH Terms