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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 27 of 27

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Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.
Huppert SS, Ilagan MX, De Strooper B, Kopan R
(2005) Dev Cell 8: 677-88
MeSH Terms: Amyloid Precursor Protein Secretases, Animals, Aspartic Acid Endopeptidases, Body Patterning, Cell Differentiation, Endopeptidases, In Situ Hybridization, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Microscopy, Electron, Scanning, Phenotype, Presenilin-1, Presenilin-2, Receptor, Notch1, Receptor, Notch2, Receptors, Cell Surface, Somites, Transcription Factors
Added January 11, 2011
1 Communities
1 Members
0 Resources
21 MeSH Terms
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.
Hadland BK, Huppert SS, Kanungo J, Xue Y, Jiang R, Gridley T, Conlon RA, Cheng AM, Kopan R, Longmore GD
(2004) Blood 104: 3097-105
MeSH Terms: Animals, Cell Differentiation, Cell Division, Gene Expression Regulation, Developmental, Hematopoiesis, Hematopoietic Stem Cells, Lac Operon, Liver, Mesoderm, Mice, Mice, Inbred Strains, Mice, Mutant Strains, Receptor, Notch1, Receptors, Cell Surface, Transcription Factors, Vascular Endothelial Growth Factor Receptor-2, Yolk Sac
Added January 11, 2011
1 Communities
1 Members
0 Resources
17 MeSH Terms
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development.
Hald J, Hjorth JP, German MS, Madsen OD, Serup P, Jensen J
(2003) Dev Biol 260: 426-37
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Biomarkers, Cell Differentiation, Cell Nucleus, Gene Expression Regulation, Developmental, Homeodomain Proteins, Islets of Langerhans, Membrane Proteins, Mice, Mice, Inbred Strains, Mice, Transgenic, Nerve Tissue Proteins, Pancreas, Rats, Receptor, Notch1, Receptors, Cell Surface, Signal Transduction, Trans-Activators, Transcription Factors, Transcriptional Activation
Added May 7, 2013
0 Communities
0 Members
6 Resources
21 MeSH Terms
Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors.
Wu Y, Liu Y, Levine EM, Rao MS
(2003) Dev Dyn 226: 675-89
MeSH Terms: Animals, Astrocytes, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cell Lineage, DNA-Binding Proteins, Epithelial Cells, Female, Gene Expression Regulation, Developmental, Homeodomain Proteins, Oligodendroglia, Pregnancy, Rats, Rats, Sprague-Dawley, Receptor, Notch1, Receptors, Cell Surface, Repressor Proteins, Spinal Cord, Stem Cells, Transcription Factor HES-1, Transcription Factors
Added November 2, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Notch1 and Jagged1 expression by the developing pulmonary vasculature.
Taichman DB, Loomes KM, Schachtner SK, Guttentag S, Vu C, Williams P, Oakey RJ, Baldwin HS
(2002) Dev Dyn 225: 166-75
MeSH Terms: Animals, Brain, Calcium-Binding Proteins, Cell Membrane, Endothelium, Vascular, Immunohistochemistry, In Situ Hybridization, Intercellular Signaling Peptides and Proteins, Jagged-1 Protein, Kidney, Lung, Membrane Proteins, Mice, Microscopy, Electron, Microscopy, Fluorescence, Protein Biosynthesis, Proteins, RNA, Messenger, Receptor, Notch1, Receptors, Cell Surface, Receptors, Notch, Reverse Transcriptase Polymerase Chain Reaction, Serrate-Jagged Proteins, Signal Transduction, Time Factors, Transcription Factors
Added June 11, 2010
1 Communities
2 Members
0 Resources
26 MeSH Terms
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R
(2000) Nature 405: 966-70
MeSH Terms: Alleles, Animals, Cloning, Molecular, Embryo, Mammalian, Embryonic and Fetal Development, Fetal Death, Gene Targeting, Germ-Line Mutation, Homozygote, Immunoglobulins, In Situ Hybridization, Ligands, Membrane Proteins, Mice, Mice, Inbred C57BL, Phenotype, Point Mutation, Protein Processing, Post-Translational, Receptor, Notch1, Receptors, Cell Surface, Receptors, Cytokine, Transcription Factors
Added January 11, 2011
1 Communities
1 Members
0 Resources
22 MeSH Terms
Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1.
Franklin JL, Berechid BE, Cutting FB, Presente A, Chambers CB, Foltz DR, Ferreira A, Nye JS
(1999) Curr Biol 9: 1448-57
MeSH Terms: Animals, Calcium-Binding Proteins, Drosophila Proteins, Gene Expression, Gene Expression Regulation, Developmental, Intercellular Signaling Peptides and Proteins, Intracellular Signaling Peptides and Proteins, Jagged-1 Protein, Membrane Proteins, Mice, Models, Neurological, Neurites, Neuroblastoma, Proteins, Receptor, Notch1, Receptors, Cell Surface, Serrate-Jagged Proteins, Signal Transduction, Transcription Factors, Tumor Cells, Cultured
Added March 20, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms