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Results: 21 to 27 of 27

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Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).
Feoktistov I, Garland EM, Goldstein AE, Zeng D, Belardinelli L, Wells JN, Biaggioni I
(2001) Biochem Pharmacol 62: 1163-73
MeSH Terms: Adenosine, Adenosine-5'-(N-ethylcarboxamide), Anti-Asthmatic Agents, Cells, Cultured, Humans, Mast Cells, Purinergic P1 Receptor Antagonists, Pyrrolidinones, Receptor, Adenosine A2B, Receptors, Purinergic P1, Structure-Activity Relationship, Vasodilator Agents, Xanthine, Xanthines
Added December 10, 2013
0 Communities
2 Members
0 Resources
14 MeSH Terms
Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation.
Grant MB, Davis MI, Caballero S, Feoktistov I, Biaggioni I, Belardinelli L
(2001) Invest Ophthalmol Vis Sci 42: 2068-73
MeSH Terms: Adenosine-5'-(N-ethylcarboxamide), Blotting, Western, Capillaries, Cell Count, Cell Division, Cell Movement, Cells, Cultured, Cyclic AMP Response Element-Binding Protein, Dose-Response Relationship, Drug, Endothelium, Vascular, Enzyme Activation, Enzyme Inhibitors, Humans, Mitogen-Activated Protein Kinases, Purinergic P1 Receptor Antagonists, Receptor, Adenosine A2B, Receptors, Purinergic P1, Retinal Vessels, Signal Transduction, Vasodilator Agents
Added December 10, 2013
0 Communities
2 Members
0 Resources
20 MeSH Terms
Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells.
Feoktistov I, Goldstein AE, Biaggioni I
(2000) Mol Pharmacol 58: 903-10
MeSH Terms: Adenosine, Cells, Cultured, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Humans, Mast Cells, Phosphorylation, Receptor, Adenosine A2A, Receptor, Adenosine A2B, Receptors, Purinergic P1, cdc42 GTP-Binding Protein
Added December 10, 2013
0 Communities
2 Members
0 Resources
11 MeSH Terms
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells.
Olanrewaju HA, Qin W, Feoktistov I, Scemama JL, Mustafa SJ
(2000) Am J Physiol Heart Circ Physiol 279: H650-6
MeSH Terms: 2-Chloroadenosine, Adenosine, Adenosine-5'-(N-ethylcarboxamide), Affinity Labels, Animals, Binding, Competitive, Cells, Cultured, Coronary Vessels, Cyclic AMP, Endothelium, Vascular, Gene Expression Regulation, Humans, Iodine Radioisotopes, Iodobenzenes, Kinetics, Phenethylamines, Purinergic P1 Receptor Antagonists, Radioligand Assay, Receptor, Adenosine A2A, Receptor, Adenosine A2B, Receptors, Purinergic P1, Reverse Transcriptase Polymerase Chain Reaction, Swine, Transcription, Genetic, Triazines, Triazoles
Added May 29, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Role of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase in adenosine A2B receptor-mediated interleukin-8 production in human mast cells.
Feoktistov I, Goldstein AE, Biaggioni I
(1999) Mol Pharmacol 55: 726-34
MeSH Terms: Adenosine, Calcium-Calmodulin-Dependent Protein Kinases, Cells, Cultured, Enzyme Activation, Humans, Interleukin-8, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase 4, Mast Cells, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Phosphorylation, Protein Kinases, Receptor, Adenosine A2B, Receptors, Purinergic P1, Signal Transduction, Tyrosine, p38 Mitogen-Activated Protein Kinases
Added December 10, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms
Adenosine A2B receptors: a novel therapeutic target in asthma?
Feoktistov I, Polosa R, Holgate ST, Biaggioni I
(1998) Trends Pharmacol Sci 19: 148-53
MeSH Terms: Anti-Asthmatic Agents, Asthma, Mast Cells, Purinergic P1 Receptor Antagonists, Receptor, Adenosine A2B, Receptors, Purinergic P1
Added December 10, 2013
0 Communities
2 Members
0 Resources
6 MeSH Terms
Adenosine A2B receptors.
Feoktistov I, Biaggioni I
(1997) Pharmacol Rev 49: 381-402
MeSH Terms: Amino Acid Sequence, Animals, Asthma, Cell Division, Heart, Intestinal Mucosa, Mast Cells, Molecular Sequence Data, Myocardial Contraction, Purinergic P1 Receptor Agonists, Receptor, Adenosine A2B, Receptors, Purinergic P1, Sequence Homology, Amino Acid, Signal Transduction, Synaptic Transmission
Added December 10, 2013
0 Communities
2 Members
0 Resources
15 MeSH Terms