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Sustained local delivery of siRNA from an injectable scaffold.
Nelson CE, Gupta MK, Adolph EJ, Shannon JM, Guelcher SA, Duvall CL
(2012) Biomaterials 33: 1154-61
MeSH Terms: Animals, Delayed-Action Preparations, Hydrogen-Ion Concentration, Injections, Mice, NIH 3T3 Cells, Nanoparticles, Polyurethanes, RNA Interference, RNA, Small Interfering, Tissue Scaffolds
Added December 5, 2013
3 Communities
2 Members
0 Resources
11 MeSH Terms
Synthesis, characterization of calcium phosphates/polyurethane composites for weight-bearing implants.
Yoshii T, Dumas JE, Okawa A, Spengler DM, Guelcher SA
(2012) J Biomed Mater Res B Appl Biomater 100: 32-40
MeSH Terms: Animals, Bone Substitutes, Calcium Phosphates, Cell Line, Durapatite, Femur, Male, Materials Testing, Mice, Polyurethanes, Rats, Rats, Sprague-Dawley, X-Ray Microtomography
Added February 23, 2016
1 Communities
1 Members
0 Resources
13 MeSH Terms
Improving bone formation in a rat femur segmental defect by controlling bone morphogenetic protein-2 release.
Brown KV, Li B, Guda T, Perrien DS, Guelcher SA, Wenke JC
(2011) Tissue Eng Part A 17: 1735-46
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Cattle, Collagen, Femur, Humans, Implants, Experimental, Kinetics, Lactic Acid, Microspheres, Osteogenesis, Polyglycolic Acid, Polylactic Acid-Polyglycolic Acid Copolymer, Polyurethanes, Rats, Recombinant Proteins, Tissue Scaffolds, Tomography, X-Ray Computed, Transforming Growth Factor beta
Added April 25, 2013
1 Communities
3 Members
0 Resources
20 MeSH Terms
Sensing and modulation of invadopodia across a wide range of rigidities.
Parekh A, Ruppender NS, Branch KM, Sewell-Loftin MK, Lin J, Boyer PD, Candiello JE, Merryman WD, Guelcher SA, Weaver AM
(2011) Biophys J 100: 573-582
MeSH Terms: Acrylic Resins, Animals, Basement Membrane, Biomechanical Phenomena, Cell Surface Extensions, Elastic Modulus, Extracellular Matrix, Microscopy, Atomic Force, Models, Biological, Polyurethanes, Pressure, Sus scrofa, Urinary Bladder
Added December 5, 2013
3 Communities
4 Members
0 Resources
13 MeSH Terms
Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds.
Hafeman AE, Zienkiewicz KJ, Zachman AL, Sung HJ, Nanney LB, Davidson JM, Guelcher SA
(2011) Biomaterials 32: 419-29
MeSH Terms: Animals, Biocompatible Materials, Cell Line, Lysine, Male, Materials Testing, Mechanics, Mice, Microscopy, Electron, Scanning, Polyesters, Polyurethanes, Rats, Rats, Sprague-Dawley, Tissue Engineering, Tissue Scaffolds, Wound Healing
Added September 21, 2012
2 Communities
3 Members
0 Resources
16 MeSH Terms
Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model.
Li B, Brown KV, Wenke JC, Guelcher SA
(2010) J Control Release 145: 221-30
MeSH Terms: Animals, Anti-Bacterial Agents, Delayed-Action Preparations, Femur, Polyurethanes, Rats, Rats, Sprague-Dawley, Vancomycin, Wound Infection
Added February 23, 2016
1 Communities
1 Members
0 Resources
9 MeSH Terms
Synthesis and characterization of an injectable allograft bone/polymer composite bone void filler with tunable mechanical properties.
Dumas JE, Zienkiewicz K, Tanner SA, Prieto EM, Bhattacharyya S, Guelcher SA
(2010) Tissue Eng Part A 16: 2505-18
MeSH Terms: Animals, Bone Demineralization Technique, Bone Substitutes, Bone Transplantation, Femoral Fractures, Injections, Materials Testing, Polyurethanes, Rats, Rats, Nude, Treatment Outcome
Added February 23, 2016
1 Communities
1 Members
0 Resources
11 MeSH Terms
A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration.
Yoshii T, Hafeman AE, Nyman JS, Esparza JM, Shinomiya K, Spengler DM, Mundy GR, Gutierrez GE, Guelcher SA
(2010) Tissue Eng Part A 16: 2369-79
MeSH Terms: Animals, Biocompatible Materials, Bone Regeneration, Bone and Bones, Cell Differentiation, Delayed-Action Preparations, Elastomers, Kinetics, Lovastatin, Male, Mice, Microscopy, Electron, Scanning, Osteogenesis, Polyurethanes, Rats, Rats, Sprague-Dawley, Tissue Scaffolds
Added March 24, 2014
1 Communities
2 Members
0 Resources
17 MeSH Terms
Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit.
Dumas JE, Davis T, Holt GE, Yoshii T, Perrien DS, Nyman JS, Boyce T, Guelcher SA
(2010) Acta Biomater 6: 2394-406
MeSH Terms: Animals, Bone and Bones, Microscopy, Electron, Scanning, Polyurethanes, Rabbits, Spectrophotometry, Infrared, Weight-Bearing
Added April 25, 2013
1 Communities
4 Members
0 Resources
7 MeSH Terms
Local delivery of tobramycin from injectable biodegradable polyurethane scaffolds.
Hafeman AE, Zienkiewicz KJ, Carney E, Litzner B, Stratton C, Wenke JC, Guelcher SA
(2010) J Biomater Sci Polym Ed 21: 95-112
MeSH Terms: Anti-Bacterial Agents, Delayed-Action Preparations, Drug Delivery Systems, Elastic Modulus, Injections, Materials Testing, Microbial Sensitivity Tests, Polyurethanes, Staphylococcus aureus, Tobramycin
Added February 23, 2016
1 Communities
1 Members
0 Resources
10 MeSH Terms