The Nogo receptor NgR1 mediates infection by mammalian reovirus.
Konopka-Anstadt JL, Mainou BA, Sutherland DM, Sekine Y, Strittmatter SM, Dermody TS
(2014) Cell Host Microbe 15
: 681-91MeSH Terms: Animals, CHO Cells, Capsid Proteins, Cell Adhesion Molecules, Cell Membrane, Cricetulus, GPI-Linked Proteins, Host-Pathogen Interactions, Humans, Mice, Mutant Strains, Myelin Proteins, Neuraminidase, Neurons, Nogo Receptor 1, Receptors, Cell Surface, Reoviridae, Reoviridae Infections, VirionAdded January 21, 2015
18 MeSH Terms
Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice.
Lippert RN, Ellacott KL, Cone RD
(2014) Endocrinology 155
: 1718-27MeSH Terms: Animals, Appetitive Behavior, Behavior, Animal, Dopamine, Dopaminergic Neurons, Female, Food Preferences, Green Fluorescent Proteins, Homeostasis, Limbic System, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Mice, Transgenic, Nerve Tissue Proteins, Ovariectomy, Promoter Regions, Genetic, Receptor, Melanocortin, Type 3, Receptor, Melanocortin, Type 4, Sex Characteristics, Ventral Tegmental AreaAdded May 27, 2014
23 MeSH Terms
Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.
Swinehart IT, Schlientz AJ, Quintanilla CA, Mortlock DP, Wellik DM
(2013) Development 140
: 4574-82MeSH Terms: Animals, Body Patterning, Bone and Bones, Chondrocytes, Connective Tissue, Endothelial Cells, Extracellular Matrix, Female, Forelimb, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Homeodomain Proteins, Male, Mice, Mice, Mutant Strains, Muscles, Mutation, Osteoblasts, TendonsAdded May 27, 2014
19 MeSH Terms
Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.
McCarthy MK, Levine RE, Procario MC, McDonnell PJ, Zhu L, Mancuso P, Crofford LJ, Aronoff DM, Weinberg JB
(2013) PLoS One 8
: e77628MeSH Terms: Adenoviridae, Animals, Chemokine CCL5, Chemokine CXCL1, Dinoprostone, Interferon-gamma, Male, Mice, Mice, Mutant Strains, Real-Time Polymerase Chain Reaction, Respiratory Tract Infections, Virus ReplicationAdded January 21, 2015
12 MeSH Terms
A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.
Liu D, Wang CJ, Judge DP, Halushka MK, Ni J, Habashi JP, Moslehi J, Bedja D, Gabrielson KL, Xu H, Qian F, Huso D, Dietz HC, Germino GG, Watnick T
(2014) J Am Soc Nephrol 25
: 81-91MeSH Terms: Animals, Disease Models, Animal, Epistasis, Genetic, Female, Fibrillin-1, Fibrillins, Genetic Association Studies, Haploinsufficiency, Heterozygote, Humans, Male, Marfan Syndrome, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Microfilament Proteins, Mutation, Polycystic Kidney, Autosomal Dominant, Signal Transduction, TRPP Cation Channels, Transforming Growth Factor beta, Vascular DiseasesAdded March 4, 2015
24 MeSH Terms
Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis.
Ma Y, Krueger JJ, Redmon SN, Uppuganti S, Nyman JS, Hahn MK, Elefteriou F
(2013) J Biol Chem 288
: 30105-30113MeSH Terms: Animals, Antidepressive Agents, Biological Transport, Active, Bone Remodeling, Bone Resorption, Humans, Mice, Mice, Mutant Strains, Morpholines, Neurons, Norepinephrine, Norepinephrine Plasma Membrane Transport Proteins, Osteoclasts, Psychomotor Disorders, Reboxetine, Sympathetic Nervous SystemAdded November 14, 2013
16 MeSH Terms
Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina.
Gordon PJ, Yun S, Clark AM, Monuki ES, Murtaugh LC, Levine EM
(2013) J Neurosci 33
: 12197-207MeSH Terms: Animals, Cell Differentiation, Female, Gene Expression Regulation, Developmental, Gene Knock-In Techniques, LIM-Homeodomain Proteins, Male, Mice, Mice, Mutant Strains, Neural Stem Cells, Neurogenesis, Pregnancy, Retina, Retinal Ganglion Cells, Retinal Rod Photoreceptor Cells, Transcription FactorsAdded November 2, 2015
16 MeSH Terms
Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.
Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL
(2013) Diabetes 62
: 875-86MeSH Terms: Animals, Cell Nucleus, DNA-Binding Proteins, Female, Gene Expression Regulation, Glucagon-Secreting Cells, Insulin-Secreting Cells, Islets of Langerhans, LIM Domain Proteins, LIM-Homeodomain Proteins, Male, Mice, Mice, Knockout, Mice, Mutant Strains, Mice, Transgenic, Organ Specificity, Organogenesis, Protein Isoforms, RNA, Messenger, Somatostatin-Secreting Cells, Transcription FactorsAdded December 5, 2013
21 MeSH Terms
A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy.
Sewell-Loftin MK, Brown CB, Baldwin HS, Merryman WD
(2012) J Heart Valve Dis 21
: 513-20MeSH Terms: Animals, Aortic Valve, Aortic Valve Insufficiency, Apolipoproteins E, Biomechanical Phenomena, Heterozygote, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Microscopy, Atomic Force, Models, Cardiovascular, Receptor, Notch1, Stress, Mechanical, SwineAdded February 12, 2015
14 MeSH Terms
Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis.
Shi M, Pedchenko V, Greer BH, Van Horn WD, Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A
(2012) J Biol Chem 287
: 35139-35152MeSH Terms: Amino Acid Substitution, Animals, Cell Line, Transformed, Collagen Type IV, Down-Regulation, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Humans, Integrin alpha1beta1, Laminin, Ligands, MAP Kinase Signaling System, Mice, Mice, Mutant Strains, Models, Molecular, Mutation, Missense, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Biosynthesis, Protein Structure, TertiaryAdded February 24, 2014
20 MeSH Terms