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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 62

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Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae.
Harper NC, Al-Greene NT, Basrai MA, Belanger KD
(2008) Curr Genet 53: 95-105
MeSH Terms: Deoxyribonucleases, Gene Deletion, Mutation, Nuclear Pore, Nuclear Pore Complex Proteins, Nuclear Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Spindle Apparatus, tRNA Methyltransferases
Added June 14, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Genomic imprinting of Dopa decarboxylase in heart and reciprocal allelic expression with neighboring Grb10.
Menheniott TR, Woodfine K, Schulz R, Wood AJ, Monk D, Giraud AS, Baldwin HS, Moore GE, Oakey RJ
(2008) Mol Cell Biol 28: 386-96
MeSH Terms: ATPases Associated with Diverse Cellular Activities, Adenosine Triphosphatases, Alleles, Animals, Base Sequence, Cytoskeletal Proteins, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, Dopa Decarboxylase, Exons, GRB10 Adaptor Protein, Genomic Imprinting, Humans, Mice, Mice, Transgenic, Microfilament Proteins, Microtubule-Associated Proteins, Myocardium, Nuclear Proteins, Oligonucleotide Array Sequence Analysis, Organ Specificity, Proteins
Added April 7, 2010
1 Communities
1 Members
0 Resources
22 MeSH Terms
Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency.
Strauss KA, Morton DH, Puffenberger EG, Hendrickson C, Robinson DL, Wagner C, Stabler SP, Allen RH, Chwatko G, Jakubowski H, Niculescu MD, Mudd SH
(2007) Mol Genet Metab 91: 165-75
MeSH Terms: Adolescent, Adult, Betaine, Brain, Brain Diseases, Child, Child, Preschool, Humans, Infant, Newborn, Methionine, Methylenetetrahydrofolate Reductase (NADPH2), Methyltransferases, Mutation, Missense, Neonatal Screening, S-Adenosylmethionine
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.
Reed-Inderbitzin E, Moreno-Miralles I, Vanden-Eynden SK, Xie J, Lutterbach B, Durst-Goodwin KL, Luce KS, Irvin BJ, Cleary ML, Brandt SJ, Hiebert SW
(2006) Oncogene 25: 5777-86
MeSH Terms: Animals, COS Cells, Chlorocebus aethiops, Core Binding Factor Alpha 2 Subunit, Histone Deacetylases, Humans, Jurkat Cells, Methyltransferases, Repressor Proteins, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.
Davis CA, Haberland M, Arnold MA, Sutherland LB, McDonald OG, Richardson JA, Childs G, Harris S, Owens GK, Olson EN
(2006) Mol Cell Biol 26: 2626-36
MeSH Terms: Amino Acid Sequence, Animals, Arteries, Biomarkers, Cell Proliferation, Cells, Cultured, Embryo, Mammalian, Gene Expression, Gene Expression Regulation, Histone Methyltransferases, Histone-Lysine N-Methyltransferase, Mice, Molecular Sequence Data, Myocytes, Smooth Muscle, Phenotype, Protein Binding, Protein Methyltransferases, Protein Structure, Tertiary, Repressor Proteins, Veins
Added May 5, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei.
Zhou W, Lepesheva GI, Waterman MR, Nes WD
(2006) J Biol Chem 281: 6290-6
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Catalysis, Enzyme Inhibitors, Ergosterol, Gas Chromatography-Mass Spectrometry, Methyltransferases, Molecular Sequence Data, Protozoan Proteins, Recombinant Proteins, Sequence Alignment, Substrate Specificity, Trypanosoma brucei brucei
Added February 12, 2015
0 Communities
2 Members
0 Resources
15 MeSH Terms
Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Pakhomova S, Luka Z, Grohmann S, Wagner C, Newcomer ME
(2004) Proteins 57: 331-7
MeSH Terms: Amino Acid Sequence, Animals, Crystallography, X-Ray, Glycine N-Methyltransferase, Humans, Kinetics, Methyltransferases, Mice, Molecular Sequence Data, Protein Conformation, Rats, Recombinant Proteins, Sequence Alignment
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Glycine N -methyltransferase deficiency: a new patient with a novel mutation.
Augoustides-Savvopoulou P, Luka Z, Karyda S, Stabler SP, Allen RH, Patsiaoura K, Wagner C, Mudd SH
(2003) J Inherit Metab Dis 26: 745-59
MeSH Terms: Child, Preschool, Glycine N-Methyltransferase, Humans, Male, Methionine, Methyltransferases, Mutation
Added January 20, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Effect of naturally occurring mutations in human glycine N-methyltransferase on activity and conformation.
Luka Z, Wagner C
(2003) Biochem Biophys Res Commun 312: 1067-72
MeSH Terms: Enzyme Activation, Escherichia coli, Genetic Variation, Glycine N-Methyltransferase, Humans, Kinetics, Methyltransferases, Mutagenesis, Site-Directed, Mutation, Protein Binding, Protein Conformation, Protein Structure, Quaternary, Protein Structure, Secondary, Recombinant Proteins, S-Adenosylmethionine, Structure-Activity Relationship, Substrate Specificity
Added January 20, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Human glycine N-methyltransferase is unfolded by urea through a compact monomer state.
Luka Z, Wagner C
(2003) Arch Biochem Biophys 420: 153-60
MeSH Terms: Dimerization, Enzyme Activation, Enzyme Reactivators, Enzyme Stability, Glycine N-Methyltransferase, Humans, Methyltransferases, Protein Conformation, Protein Denaturation, Protein Folding, Protein Structure, Secondary, Urea
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms