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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 44

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5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
Luka Z, Pakhomova S, Loukachevitch LV, Egli M, Newcomer ME, Wagner C
(2007) J Biol Chem 282: 4069-75
MeSH Terms: Animals, Binding Sites, Carrier Proteins, Crystallography, X-Ray, Enzyme Inhibitors, Folate Receptors, GPI-Anchored, Folic Acid, Glycine N-Methyltransferase, Liver, Protein Binding, Protein Interaction Mapping, Protein Subunits, Rats, Receptors, Cell Surface, Tetrahydrofolates
Added March 5, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme.
Luka Z, Capdevila A, Mato JM, Wagner C
(2006) Transgenic Res 15: 393-7
MeSH Terms: Animals, DNA Methylation, Disease Models, Animal, Genetic Techniques, Glycine N-Methyltransferase, Homozygote, Humans, Liver, Metabolism, Inborn Errors, Mice, Mice, Knockout, Mice, Transgenic, Mutation, Plasmids, Promoter Regions, Genetic
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Identification of phosphorylation sites in glycine N-methyltransferase from rat liver.
Luka Z, Ham AJ, Norris JL, Yeo EJ, Yermalitsky V, Glenn B, Caprioli RM, Liebler DC, Wagner C
(2006) Protein Sci 15: 785-94
MeSH Terms: Amino Acid Sequence, Animals, Cyclic AMP-Dependent Protein Kinases, Glycine N-Methyltransferase, Hepatocytes, Liver, Mass Spectrometry, Molecular Sequence Data, Phosphorylation, Protein Isoforms, Protein Structure, Secondary, Rats, Recombinant Proteins, Serine, Spectrometry, Mass, Electrospray Ionization
Added March 5, 2014
0 Communities
4 Members
0 Resources
15 MeSH Terms
Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Pakhomova S, Luka Z, Grohmann S, Wagner C, Newcomer ME
(2004) Proteins 57: 331-7
MeSH Terms: Amino Acid Sequence, Animals, Crystallography, X-Ray, Glycine N-Methyltransferase, Humans, Kinetics, Methyltransferases, Mice, Molecular Sequence Data, Protein Conformation, Rats, Recombinant Proteins, Sequence Alignment
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Glycine N -methyltransferase deficiency: a new patient with a novel mutation.
Augoustides-Savvopoulou P, Luka Z, Karyda S, Stabler SP, Allen RH, Patsiaoura K, Wagner C, Mudd SH
(2003) J Inherit Metab Dis 26: 745-59
MeSH Terms: Child, Preschool, Glycine N-Methyltransferase, Humans, Male, Methionine, Methyltransferases, Mutation
Added January 20, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Effect of naturally occurring mutations in human glycine N-methyltransferase on activity and conformation.
Luka Z, Wagner C
(2003) Biochem Biophys Res Commun 312: 1067-72
MeSH Terms: Enzyme Activation, Escherichia coli, Genetic Variation, Glycine N-Methyltransferase, Humans, Kinetics, Methyltransferases, Mutagenesis, Site-Directed, Mutation, Protein Binding, Protein Conformation, Protein Structure, Quaternary, Protein Structure, Secondary, Recombinant Proteins, S-Adenosylmethionine, Structure-Activity Relationship, Substrate Specificity
Added January 20, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Human glycine N-methyltransferase is unfolded by urea through a compact monomer state.
Luka Z, Wagner C
(2003) Arch Biochem Biophys 420: 153-60
MeSH Terms: Dimerization, Enzyme Activation, Enzyme Reactivators, Enzyme Stability, Glycine N-Methyltransferase, Humans, Methyltransferases, Protein Conformation, Protein Denaturation, Protein Folding, Protein Structure, Secondary, Urea
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Expression and purification of glycine N-methyltransferases in Escherichia coli.
Luka Z, Wagner C
(2003) Protein Expr Purif 28: 280-6
MeSH Terms: Amino Acid Sequence, Animals, Electrophoresis, Polyacrylamide Gel, Escherichia coli, Gene Expression Regulation, Enzymologic, Glycine N-Methyltransferase, Humans, Methyltransferases, Mice, Molecular Sequence Data, Rats, Recombinant Fusion Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Mutations in human glycine N-methyltransferase give insights into its role in methionine metabolism.
Luka Z, Cerone R, Phillips JA, Mudd HS, Wagner C
(2002) Hum Genet 110: 68-74
MeSH Terms: Amino Acid Substitution, Binding Sites, Carrier Proteins, DNA Primers, Exons, Glycine N-Methyltransferase, Humans, Methionine, Methyltransferases, Models, Molecular, Mutation, Missense, Polymerase Chain Reaction, Protein Conformation, Protein Subunits, Reverse Transcriptase Polymerase Chain Reaction
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia.
Mudd SH, Cerone R, Schiaffino MC, Fantasia AR, Minniti G, Caruso U, Lorini R, Watkins D, Matiaszuk N, Rosenblatt DS, Schwahn B, Rozen R, LeGros L, Kotb M, Capdevila A, Luka Z, Finkelstein JD, Tangerman A, Stabler SP, Allen RH, Wagner C
(2001) J Inherit Metab Dis 24: 448-64
MeSH Terms: Alanine Transaminase, Aspartate Aminotransferases, Child, Child, Preschool, Diet, Female, Glycine N-Methyltransferase, Hepatomegaly, Humans, Liver, Methionine, Methyltransferases, S-Adenosylmethionine, Sarcosine
Added January 20, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms