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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 370

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Discoidin Domain Receptor 2, a Potential Therapeutic Target in Lung Fibrosis.
Borza CM, Pozzi A, Plosa EJ
(2018) Am J Respir Cell Mol Biol 59: 277-278
MeSH Terms: Apoptosis, Discoidin Domain Receptor 2, Fibroblasts, Proto-Oncogene Proteins c-akt, Signal Transduction
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.
Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK
(2018) Cancer Res 78: 3135-3146
MeSH Terms: Animals, Carcinogenesis, Carcinoma, Renal Cell, Cell Line, Tumor, Chromosomes, Human, Pair 3, Fibroblasts, Gene Knockdown Techniques, Genomic Instability, Haploinsufficiency, Histone-Lysine N-Methyltransferase, Histones, Humans, Kidney Neoplasms, Kidney Tubules, Proximal, Lysine, Methylation, Mice, Micronuclei, Chromosome-Defective, Microtubules
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Successful Establishment of Primary Type II Alveolar Epithelium with 3D Organotypic Coculture.
Sucre JMS, Jetter CS, Loomans H, Williams J, Plosa EJ, Benjamin JT, Young LR, Kropski JA, Calvi CL, Kook S, Wang P, Gleaves L, Eskaros A, Goetzl L, Blackwell TS, Guttentag SH, Zijlstra A
(2018) Am J Respir Cell Mol Biol 59: 158-166
MeSH Terms: Cell Communication, Cells, Cultured, Coculture Techniques, Epithelial Cells, Fibroblasts, Humans, Lung, Lung Injury, Phenotype
Added April 1, 2019
0 Communities
3 Members
0 Resources
9 MeSH Terms
Autochthonous tumors driven by loss have an ongoing requirement for the RBP2 histone demethylase.
McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG
(2018) Proc Natl Acad Sci U S A 115: E3741-E3748
MeSH Terms: Alleles, Animals, DNA-Binding Proteins, Echocardiography, Enzyme Activation, Fibroblasts, Genes, Retinoblastoma, Heart Septal Defects, Histone Code, Integrases, Jumonji Domain-Containing Histone Demethylases, Mice, Mice, Inbred C57BL, Molecular Targeted Therapy, Neoplasm Proteins, Pituitary Neoplasms, Recombinant Fusion Proteins, Retinoblastoma Protein, Tamoxifen, Thyroid Neoplasms, Transgenes
Added April 22, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
Renal fibrosis: Primacy of the proximal tubule.
Gewin LS
(2018) Matrix Biol 68-69: 248-262
MeSH Terms: Animals, Disease Progression, Extracellular Matrix, Fibrosis, Humans, Kidney Tubules, Proximal, Macrophages, Myofibroblasts, Renal Insufficiency, Chronic
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?
Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G, Maher TM, Molina-Molina M, Noble PW, Raghu G, Richeldi L, Schwarz MI, Selman M, Wuyts WA, Schwartz DA
(2018) Lancet Respir Med 6: 154-160
MeSH Terms: Fibroblasts, Humans, Idiopathic Pulmonary Fibrosis, Lung, Risk Factors
Added March 21, 2018
0 Communities
1 Members
0 Resources
5 MeSH Terms
Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials.
Lampi MC, Reinhart-King CA
(2018) Sci Transl Med 10:
MeSH Terms: Animals, Cell Differentiation, Extracellular Matrix, Fibrosis, Humans, Myofibroblasts, Transforming Growth Factor beta
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.
Kropski JA, Blackwell TS
(2018) J Clin Invest 128: 64-73
MeSH Terms: Animals, Apoptosis, Endoplasmic Reticulum Stress, Fibrosis, Humans, Inflammation, Macrophages, Molecular Chaperones, Myofibroblasts, Signal Transduction, Unfolded Protein Response
Added March 21, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Non-visual arrestins regulate the focal adhesion formation via small GTPases RhoA and Rac1 independently of GPCRs.
Cleghorn WM, Bulus N, Kook S, Gurevich VV, Zent R, Gurevich EV
(2018) Cell Signal 42: 259-269
MeSH Terms: Actin Cytoskeleton, Animals, Cell Adhesion, Cell Line, Cell Movement, Fibroblasts, Focal Adhesions, Gene Expression Regulation, Mice, Neuropeptides, Receptors, G-Protein-Coupled, Signal Transduction, beta-Arrestin 1, beta-Arrestin 2, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, rho GTP-Binding Proteins, rhoA GTP-Binding Protein
Added March 14, 2018
0 Communities
1 Members
0 Resources
18 MeSH Terms
Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.
Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ
(2017) J Cell Biol 216: 3799-3816
MeSH Terms: Cancer-Associated Fibroblasts, Cell Communication, Cell Line, Tumor, Cell Movement, Coculture Techniques, Extracellular Matrix, Fibronectins, Humans, Integrin alpha5beta1, Male, Mechanotransduction, Cellular, Neoplasm Invasiveness, Nonmuscle Myosin Type IIA, Prostatic Neoplasms, RNA Interference, Receptor, Platelet-Derived Growth Factor alpha, Time Factors, Transfection, Tumor Cells, Cultured, Tumor Microenvironment
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms