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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 30

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MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication.
Deming DJ, Graham RL, Denison MR, Baric RS
(2006) Adv Exp Med Biol 581: 101-4
MeSH Terms: Animals, Coronavirus Papain-Like Proteases, Murine hepatitis virus, Mutation, Open Reading Frames, Papain, Polyproteins, Protein Processing, Post-Translational, RNA-Dependent RNA Polymerase, Viral Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Replication of murine hepatitis virus is regulated by papain-like proteinase 1 processing of nonstructural proteins 1, 2, and 3.
Graham RL, Denison MR
(2006) J Virol 80: 11610-20
MeSH Terms: Animals, Coronavirus Papain-Like Proteases, Murine hepatitis virus, Papain, Protein Processing, Post-Translational, Viral Nonstructural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.
Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H
(2006) J Biol Chem 281: 3198-203
MeSH Terms: Angiotensin-Converting Enzyme 2, Animals, Carboxypeptidases, Cathepsin L, Cathepsins, Cell Line, Chlorocebus aethiops, Coronavirus, Cysteine Endopeptidases, Endosomes, Green Fluorescent Proteins, Humans, Lysosomes, Membrane Glycoproteins, Peptidyl-Dipeptidase A, Retroviridae, SARS Virus, Species Specificity, Vero Cells, Viral Envelope Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice.
Yount B, Roberts RS, Sims AC, Deming D, Frieman MB, Sparks J, Denison MR, Davis N, Baric RS
(2005) J Virol 79: 14909-22
MeSH Terms: Animals, Coronavirus Infections, Mice, Open Reading Frames, SARS Virus, Viral Proteins, Viral Structural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice.
Sperry SM, Kazi L, Graham RL, Baric RS, Weiss SR, Denison MR
(2005) J Virol 79: 3391-400
MeSH Terms: Amino Acid Substitution, Animals, Coronavirus Infections, DNA, Complementary, DNA, Viral, Disease Models, Animal, Mice, Molecular Sequence Data, Murine hepatitis virus, Open Reading Frames, Sequence Analysis, DNA, Viral Nonstructural Proteins, Viral Plaque Assay, Virulence, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Moderate mutation rate in the SARS coronavirus genome and its implications.
Zhao Z, Li H, Wu X, Zhong Y, Zhang K, Zhang YP, Boerwinkle E, Fu YX
(2004) BMC Evol Biol 4: 21
MeSH Terms: Coronavirus, Evolution, Molecular, Genes, Viral, Genome, Viral, Mutagenesis, Phylogeny, SARS Virus, Viral Structural Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Coronavirus replication complex formation utilizes components of cellular autophagy.
Prentice E, Jerome WG, Yoshimori T, Mizushima N, Denison MR
(2004) J Biol Chem 279: 10136-41
MeSH Terms: Adenine, Animals, Autophagy, Autophagy-Related Protein 12, Blotting, Western, Cell Division, Cell Line, Coronavirus, Cytoplasm, Embryo, Mammalian, Endoplasmic Reticulum, Rough, Mice, Microscopy, Electron, Microscopy, Fluorescence, Microtubule-Associated Proteins, Phylogeny, Protein Binding, Protein Transport, Proteins, Saccharomyces cerevisiae Proteins, Stem Cells, Time Factors
Added December 10, 2013
0 Communities
2 Members
0 Resources
22 MeSH Terms
Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes.
Sims AC, Ostermann J, Denison MR
(2000) J Virol 74: 5647-54
MeSH Terms: Animals, Antigens, CD, Cell Fractionation, Cell Line, Centrifugation, Density Gradient, Coronavirus M Proteins, DNA Helicases, Endoplasmic Reticulum, Endosomes, Fluorescent Antibody Technique, Golgi Apparatus, Intracellular Membranes, Lysosome-Associated Membrane Glycoproteins, Lysosomes, Membrane Glycoproteins, Mice, Microscopy, Confocal, Molecular Weight, Murine hepatitis virus, Nucleocapsid, Nucleocapsid Proteins, RNA, Viral, RNA-Dependent RNA Polymerase, Triiodobenzoic Acids, Viral Matrix Proteins, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
26 MeSH Terms
Expression, purification, and activity of recombinant MHV-A59 3CLpro.
Sims AC, Lu XT, Denison MR
(1998) Adv Exp Med Biol 440: 129-34
MeSH Terms: Animals, Cloning, Molecular, Coronavirus 3C Proteases, Cysteine Endopeptidases, Gene Expression, Mice, Murine hepatitis virus, Recombinant Fusion Proteins, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Processing of the MHV-A59 gene 1 polyprotein by the 3C-like proteinase.
Denison MR, Sims AC, Gibson CA, Lu XT
(1998) Adv Exp Med Biol 440: 121-7
MeSH Terms: Animals, Binding Sites, Cell Line, Coronavirus 3C Proteases, Cysteine Endopeptidases, Mice, Murine hepatitis virus, Protein Precursors, Protein Processing, Post-Translational, Proteins, Rabbits, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms