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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 78

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Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.
West J, Austin E, Fessel JP, Loyd J, Hamid R
(2014) Drug Discov Today 19: 1241-5
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Humans, Hypertension, Pulmonary, Signal Transduction
Added May 20, 2014
0 Communities
5 Members
0 Resources
5 MeSH Terms
BMP pathway regulation of and by macrophages.
Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K
(2014) PLoS One 9: e94119
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Cells, Cultured, Coculture Techniques, Hypertension, Pulmonary, Macrophages, Mice, Mice, Transgenic, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Signal Transduction, Smad Proteins
Added April 10, 2014
2 Communities
3 Members
0 Resources
12 MeSH Terms
Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension.
Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW
(2014) Am J Respir Crit Care Med 189: 1110-20
MeSH Terms: Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Cytochrome P-450 Enzyme System, Disease Progression, Familial Primary Pulmonary Hypertension, Female, Haplotypes, Heterozygote, Humans, Hypertension, Pulmonary, Intramolecular Oxidoreductases, Male, Mutation, Polymerase Chain Reaction, Polymorphism, Genetic
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Genetics and genomics of pulmonary arterial hypertension.
Soubrier F, Chung WK, Machado R, Grünig E, Aldred M, Geraci M, Loyd JE, Elliott CG, Trembath RC, Newman JH, Humbert M
(2013) J Am Coll Cardiol 62: D13-21
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Genetic Predisposition to Disease, Genome-Wide Association Study, Genomics, Humans, Hypertension, Pulmonary, Mutation
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension.
Hemnes AR, Brittain EL, Trammell AW, Fessel JP, Austin ED, Penner N, Maynard KB, Gleaves L, Talati M, Absi T, Disalvo T, West J
(2014) Am J Respir Crit Care Med 189: 325-34
MeSH Terms: Animals, Biomarkers, Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Ceramides, Familial Primary Pulmonary Hypertension, Genetic Markers, Humans, Hypertension, Pulmonary, Hypertrophy, Right Ventricular, Lipolysis, Mice, Mice, Transgenic, Mutation, Oligonucleotide Array Sequence Analysis, Oxidation-Reduction, Triglycerides
Added February 28, 2014
2 Communities
4 Members
0 Resources
17 MeSH Terms
Abnormal trafficking of endogenously expressed BMPR2 mutant allelic products in patients with heritable pulmonary arterial hypertension.
Frump AL, Lowery JW, Hamid R, Austin ED, de Caestecker M
(2013) PLoS One 8: e80319
MeSH Terms: Alleles, Animals, Bone Morphogenetic Protein Receptors, Type II, Cells, Cultured, Familial Primary Pulmonary Hypertension, Female, Humans, Hypertension, Pulmonary, Male, Mice, Mutation, Nonsense Mediated mRNA Decay, Protein Transport
Added November 21, 2013
2 Communities
3 Members
0 Resources
13 MeSH Terms
Heritable forms of pulmonary arterial hypertension.
Austin ED, Loyd JE
(2013) Semin Respir Crit Care Med 34: 568-80
MeSH Terms: Activin Receptors, Type II, Antigens, CD, Bone Morphogenetic Protein Receptors, Type II, Caveolin 1, Endoglin, Familial Primary Pulmonary Hypertension, Female, Gene-Environment Interaction, Genetic Counseling, Genetic Testing, Germ-Line Mutation, Humans, Hypertension, Pulmonary, Male, Nerve Tissue Proteins, Penetrance, Potassium Channels, Tandem Pore Domain, Pregnancy, Preimplantation Diagnosis, Receptors, Cell Surface, Sex Distribution, TGF-beta Superfamily Proteins
Added March 20, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.
Fessel JP, Flynn CR, Robinson LJ, Penner NL, Gladson S, Kang CJ, Wasserman DH, Hemnes AR, West JD
(2013) Am J Respir Cell Mol Biol 49: 778-87
MeSH Terms: Animals, Arterial Pressure, Bone Morphogenetic Protein Receptors, Type II, Cardiac Output, Cell Line, Tumor, Disease Models, Animal, Endothelial Cells, Familial Primary Pulmonary Hypertension, Humans, Hyperoxia, Hypertension, Pulmonary, Lung, Lung Injury, Mice, Mice, Transgenic, Mitochondria, Mitochondrial Membranes, Mutation, Oxidative Stress, Pulmonary Artery, Reactive Oxygen Species, Stress, Physiological, Ventricular Function, Right, Ventricular Pressure
Added April 17, 2014
2 Communities
2 Members
0 Resources
24 MeSH Terms
Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines.
Langenfeld E, Hong CC, Lanke G, Langenfeld J
(2013) PLoS One 8: e61256
MeSH Terms: Bone Morphogenetic Protein 2, Bone Morphogenetic Protein Receptors, Type I, Bronchi, Cell Death, Cell Line, Tumor, Cell Proliferation, Cell Survival, Clone Cells, Endothelial Cells, Epithelial Cells, Gene Knockdown Techniques, Humans, Inhibitor of Differentiation Proteins, Lung Neoplasms, Pyrazoles, Pyrimidines, Signal Transduction, Smad Proteins
Added September 20, 2013
1 Communities
1 Members
0 Resources
18 MeSH Terms
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.
Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay É, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S
(2013) J Am Heart Assoc 2: e005157
MeSH Terms: Adult, Aged, Animals, Apoptosis, Arterial Pressure, Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Cell Proliferation, Cells, Cultured, Disease Models, Animal, Familial Primary Pulmonary Hypertension, Female, Glycation End Products, Advanced, Humans, Hypertension, Pulmonary, Hypertrophy, Right Ventricular, Hypoxia, Indoles, Male, Middle Aged, Monocrotaline, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, PPAR gamma, Pulmonary Artery, Pyrroles, RNA Interference, Rats, Rats, Sprague-Dawley, Receptor for Advanced Glycation End Products, Receptors, Immunologic, S100 Proteins, STAT3 Transcription Factor, Signal Transduction, Transfection, Up-Regulation
Added August 4, 2015
1 Communities
1 Members
0 Resources
36 MeSH Terms