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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 74

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Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa.
Murphy AJ, Axt JR, de Caestecker C, Pierce J, Correa H, Seeley EH, Caprioli RM, Newton MW, de Caestecker MP, Lovvorn HN
(2012) Int J Cancer 131: E983-94
MeSH Terms: Africa South of the Sahara, Apoptosis Regulatory Proteins, Child, Preschool, Female, Genes, Wilms Tumor, Humans, Infant, Kidney Neoplasms, Male, Mass Spectrometry, Mutation, Nuclear Proteins, Prognosis, Trans-Activators, Transcription Factors, Tumor Suppressor Protein p53, Wilms Tumor, beta Catenin
Added January 10, 2014
2 Communities
4 Members
0 Resources
18 MeSH Terms
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells.
Sehdev V, Peng D, Soutto M, Washington MK, Revetta F, Ecsedy J, Zaika A, Rau TT, Schneider-Stock R, Belkhiri A, El-Rifai W
(2012) Mol Cancer Ther 11: 763-74
MeSH Terms: Adenocarcinoma, Animals, Antineoplastic Agents, Apoptosis, Apoptosis Regulatory Proteins, Aurora Kinase A, Aurora Kinases, Azepines, Blotting, Western, Cell Cycle Checkpoints, Cell Line, Cell Line, Tumor, Cell Survival, Cisplatin, Drug Synergism, Esophageal Neoplasms, Esophagus, Female, Gene Expression, Humans, Mice, Mice, Nude, Phosphorylation, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, Pyrimidines, Reverse Transcriptase Polymerase Chain Reaction, Xenograft Model Antitumor Assays
Added September 3, 2013
1 Communities
4 Members
0 Resources
29 MeSH Terms
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.
Brown AC, Adams D, de Caestecker M, Yang X, Friesel R, Oxburgh L
(2011) Development 138: 5099-112
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Lineage, Cells, Cultured, Epidermal Growth Factor, Fibroblast Growth Factors, Galactosides, In Situ Nick-End Labeling, Indoles, Membrane Proteins, Mice, Microscopy, Fluorescence, Nephrons, Nuclear Proteins, Phosphatidylinositol 3-Kinases, Phosphoproteins, Polymerase Chain Reaction, Receptor Protein-Tyrosine Kinases, Signal Transduction, Trans-Activators, ras Proteins
Added March 20, 2014
2 Communities
1 Members
0 Resources
23 MeSH Terms
β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.
Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R
(2011) Am J Pathol 179: 3045-55
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Transformation, Neoplastic, Exons, Genes, ras, Humans, Inhibitor of Apoptosis Proteins, Kidney Neoplasms, Kidney Tubules, Proximal, MAP Kinase Signaling System, Mice, Mice, Transgenic, Mutation, Nuclear Proteins, PAX2 Transcription Factor, PAX8 Transcription Factor, Paired Box Transcription Factors, Phosphatidylinositol 3-Kinase, Phosphatidylinositol 3-Kinases, Repressor Proteins, Signal Transduction, Survivin, Wilms Tumor, beta Catenin
Added February 17, 2014
4 Communities
5 Members
0 Resources
24 MeSH Terms
Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice.
Novitskaya T, Baserga M, de Caestecker MP
(2011) Endocrinology 152: 2503-16
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Brain, Disease Models, Animal, Female, Fetal Growth Retardation, Gestational Age, Humans, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Kidney, Liver, Mice, Mice, Knockout, Nuclear Proteins, Organ Size, Organ Specificity, Pregnancy, Pregnancy Complications, Receptor, IGF Type 1, Receptor, Insulin, Signal Transduction, Trans-Activators
Added November 21, 2013
2 Communities
1 Members
0 Resources
23 MeSH Terms
Mutated beta-catenin evades a microRNA-dependent regulatory loop.
Veronese A, Visone R, Consiglio J, Acunzo M, Lupini L, Kim T, Ferracin M, Lovat F, Miotto E, Balatti V, D'Abundo L, Gramantieri L, Bolondi L, Pekarsky Y, Perrotti D, Negrini M, Croce CM
(2011) Proc Natl Acad Sci U S A 108: 4840-5
MeSH Terms: Apoptosis Regulatory Proteins, Cell Line, Tumor, Genetic Loci, HEK293 Cells, Humans, Insulin-Like Growth Factor II, Introns, MicroRNAs, Mutation, Proto-Oncogene Proteins, Transcription Factors, beta Catenin
Added December 22, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven.
Zou S, Chang J, LaFever L, Tang W, Johnson EL, Hu J, Wilk R, Krause HM, Drummond-Barbosa D, Irusta PM
(2011) Cell Cycle 10: 989-98
MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Animals, Apoptosis Regulatory Proteins, Cell Cycle Proteins, Cell Division, Drosophila Proteins, Drosophila melanogaster, G2 Phase, Histones, Humans, Membrane Proteins, Molecular Sequence Data, Phosphorylation, RNA Interference, Sequence Alignment, Sequence Homology, Amino Acid
Added March 19, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.
Brooks C, Cho SG, Wang CY, Yang T, Dong Z
(2011) Am J Physiol Cell Physiol 300: C447-55
MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Cell Line, Cells, Cultured, Dynamins, Enzyme Activation, GTP Phosphohydrolases, Gene Knockdown Techniques, HeLa Cells, Humans, Membrane Fusion, Membrane Transport Proteins, Mice, Mice, Knockout, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Diseases, Mitochondrial Membrane Transport Proteins, Mitochondrial Proteins, RNA Interference, Rats, Stress, Physiological, bcl-2-Associated X Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.
Berger SB, Romero X, Ma C, Wang G, Faubion WA, Liao G, Compeer E, Keszei M, Rameh L, Wang N, Boes M, Regueiro JR, Reinecker HC, Terhorst C
(2010) Nat Immunol 11: 920-7
MeSH Terms: Animals, Antigens, CD, Apoptosis Regulatory Proteins, Bacterial Proteins, Beclin-1, Cells, Cultured, Endosomal Sorting Complexes Required for Transport, Escherichia coli, Escherichia coli Infections, Macrophages, Male, Membrane Glycoproteins, Mice, Mice, Inbred BALB C, Mice, Knockout, Molecular Chaperones, NADPH Oxidase 2, NADPH Oxidases, Phagocytosis, Phagosomes, Phosphatidylinositol 3-Kinases, Porins, Protein Serine-Threonine Kinases, Receptors, Cell Surface, Salmonella Infections, Salmonella typhimurium, Signaling Lymphocytic Activation Molecule Family Member 1, Vacuolar Sorting Protein VPS15
Added December 10, 2018
0 Communities
1 Members
0 Resources
28 MeSH Terms
A role for proapoptotic Bax and Bak in T-cell differentiation and transformation.
Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S
(2010) Blood 116: 5237-46
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Transformation, Neoplastic, Coculture Techniques, Lymphoma, B-Cell, Mice, Mice, Knockout, Stem Cells, Stromal Cells, T-Lymphocytes, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added September 7, 2011
1 Communities
3 Members
0 Resources
13 MeSH Terms