Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa.
Murphy AJ, Axt JR, de Caestecker C, Pierce J, Correa H, Seeley EH, Caprioli RM, Newton MW, de Caestecker MP, Lovvorn HN
(2012) Int J Cancer 131
: E983-94MeSH Terms: Africa South of the Sahara, Apoptosis Regulatory Proteins, Child, Preschool, Female, Genes, Wilms Tumor, Humans, Infant, Kidney Neoplasms, Male, Mass Spectrometry, Mutation, Nuclear Proteins, Prognosis, Trans-Activators, Transcription Factors, Tumor Suppressor Protein p53, Wilms Tumor, beta CateninAdded January 10, 2014
18 MeSH Terms
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells.
Sehdev V, Peng D, Soutto M, Washington MK, Revetta F, Ecsedy J, Zaika A, Rau TT, Schneider-Stock R, Belkhiri A, El-Rifai W
(2012) Mol Cancer Ther 11
: 763-74MeSH Terms: Adenocarcinoma, Animals, Antineoplastic Agents, Apoptosis, Apoptosis Regulatory Proteins, Aurora Kinase A, Aurora Kinases, Azepines, Blotting, Western, Cell Cycle Checkpoints, Cell Line, Cell Line, Tumor, Cell Survival, Cisplatin, Drug Synergism, Esophageal Neoplasms, Esophagus, Female, Gene Expression, Humans, Mice, Mice, Nude, Phosphorylation, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, Pyrimidines, Reverse Transcriptase Polymerase Chain Reaction, Xenograft Model Antitumor AssaysAdded September 3, 2013
29 MeSH Terms
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.
Brown AC, Adams D, de Caestecker M, Yang X, Friesel R, Oxburgh L
(2011) Development 138
: 5099-112MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Lineage, Cells, Cultured, Epidermal Growth Factor, Fibroblast Growth Factors, Galactosides, In Situ Nick-End Labeling, Indoles, Membrane Proteins, Mice, Microscopy, Fluorescence, Nephrons, Nuclear Proteins, Phosphatidylinositol 3-Kinases, Phosphoproteins, Polymerase Chain Reaction, Receptor Protein-Tyrosine Kinases, Signal Transduction, Trans-Activators, ras ProteinsAdded March 20, 2014
23 MeSH Terms
β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.
Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R
(2011) Am J Pathol 179
: 3045-55MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Transformation, Neoplastic, Exons, Genes, ras, Humans, Inhibitor of Apoptosis Proteins, Kidney Neoplasms, Kidney Tubules, Proximal, MAP Kinase Signaling System, Mice, Mice, Transgenic, Mutation, Nuclear Proteins, PAX2 Transcription Factor, PAX8 Transcription Factor, Paired Box Transcription Factors, Phosphatidylinositol 3-Kinase, Phosphatidylinositol 3-Kinases, Repressor Proteins, Signal Transduction, Survivin, Wilms Tumor, beta CateninAdded February 17, 2014
24 MeSH Terms
Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice.
Novitskaya T, Baserga M, de Caestecker MP
(2011) Endocrinology 152
: 2503-16MeSH Terms: Animals, Apoptosis Regulatory Proteins, Brain, Disease Models, Animal, Female, Fetal Growth Retardation, Gestational Age, Humans, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Kidney, Liver, Mice, Mice, Knockout, Nuclear Proteins, Organ Size, Organ Specificity, Pregnancy, Pregnancy Complications, Receptor, IGF Type 1, Receptor, Insulin, Signal Transduction, Trans-ActivatorsAdded November 21, 2013
23 MeSH Terms
Mutated beta-catenin evades a microRNA-dependent regulatory loop.
Veronese A, Visone R, Consiglio J, Acunzo M, Lupini L, Kim T, Ferracin M, Lovat F, Miotto E, Balatti V, D'Abundo L, Gramantieri L, Bolondi L, Pekarsky Y, Perrotti D, Negrini M, Croce CM
(2011) Proc Natl Acad Sci U S A 108
: 4840-5MeSH Terms: Apoptosis Regulatory Proteins, Cell Line, Tumor, Genetic Loci, HEK293 Cells, Humans, Insulin-Like Growth Factor II, Introns, MicroRNAs, Mutation, Proto-Oncogene Proteins, Transcription Factors, beta CateninAdded December 22, 2013
12 MeSH Terms
Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven.
Zou S, Chang J, LaFever L, Tang W, Johnson EL, Hu J, Wilk R, Krause HM, Drummond-Barbosa D, Irusta PM
(2011) Cell Cycle 10
: 989-98MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Animals, Apoptosis Regulatory Proteins, Cell Cycle Proteins, Cell Division, Drosophila Proteins, Drosophila melanogaster, G2 Phase, Histones, Humans, Membrane Proteins, Molecular Sequence Data, Phosphorylation, RNA Interference, Sequence Alignment, Sequence Homology, Amino AcidAdded March 19, 2017
17 MeSH Terms
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.
Brooks C, Cho SG, Wang CY, Yang T, Dong Z
(2011) Am J Physiol Cell Physiol 300
: C447-55MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Cell Line, Cells, Cultured, Dynamins, Enzyme Activation, GTP Phosphohydrolases, Gene Knockdown Techniques, HeLa Cells, Humans, Membrane Fusion, Membrane Transport Proteins, Mice, Mice, Knockout, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Diseases, Mitochondrial Membrane Transport Proteins, Mitochondrial Proteins, RNA Interference, Rats, Stress, Physiological, bcl-2-Associated X ProteinAdded September 12, 2016
24 MeSH Terms
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.
Berger SB, Romero X, Ma C, Wang G, Faubion WA, Liao G, Compeer E, Keszei M, Rameh L, Wang N, Boes M, Regueiro JR, Reinecker HC, Terhorst C
(2010) Nat Immunol 11
: 920-7MeSH Terms: Animals, Antigens, CD, Apoptosis Regulatory Proteins, Bacterial Proteins, Beclin-1, Cells, Cultured, Endosomal Sorting Complexes Required for Transport, Escherichia coli, Escherichia coli Infections, Macrophages, Male, Membrane Glycoproteins, Mice, Mice, Inbred BALB C, Mice, Knockout, Molecular Chaperones, NADPH Oxidase 2, NADPH Oxidases, Phagocytosis, Phagosomes, Phosphatidylinositol 3-Kinases, Porins, Protein Serine-Threonine Kinases, Receptors, Cell Surface, Salmonella Infections, Salmonella typhimurium, Signaling Lymphocytic Activation Molecule Family Member 1, Vacuolar Sorting Protein VPS15Added December 10, 2018
28 MeSH Terms
A role for proapoptotic Bax and Bak in T-cell differentiation and transformation.
Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S
(2010) Blood 116
: 5237-46MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Transformation, Neoplastic, Coculture Techniques, Lymphoma, B-Cell, Mice, Mice, Knockout, Stem Cells, Stromal Cells, T-Lymphocytes, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X ProteinAdded September 7, 2011
13 MeSH Terms