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Results: 21 to 30 of 75

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PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
Nakazawa Y, Huye LE, Salsman VS, Leen AM, Ahmed N, Rollins L, Dotti G, Gottschalk SM, Wilson MH, Rooney CM
(2011) Mol Ther 19: 2133-43
MeSH Terms: Animals, Antigen Presentation, Antigens, CD19, Brain Neoplasms, Cell Line, Tumor, Coculture Techniques, Enzyme-Linked Immunosorbent Assay, Epstein-Barr Virus Infections, Flow Cytometry, Herpesvirus 4, Human, Humans, Immunotherapy, Male, Mice, Mice, Inbred NOD, Mice, SCID, Receptor, ErbB-2, Receptors, Antigen, Recombinant Fusion Proteins, T-Lymphocytes, Cytotoxic, Transduction, Genetic, Tumor Cells, Cultured
Added August 22, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors.
Joyce S, Girardi E, Zajonc DM
(2011) J Immunol 187: 1081-9
MeSH Terms: Animals, Antigen Presentation, Galactosylceramides, Glycolipids, Humans, Immunological Synapses, Inflammation, Inflammation Mediators, Ligands, Lipid Metabolism, Natural Killer T-Cells
Added May 19, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens.
Dragovic SM, Hill T, Christianson GJ, Kim S, Elliott T, Scott D, Roopenian DC, Van Kaer L, Joyce S
(2011) J Immunol 186: 6683-92
MeSH Terms: ATP-Binding Cassette Transporters, Aminopeptidases, Antigen Presentation, Antigens, Bacterial, Cytoplasm, Endoplasmic Reticulum, Histocompatibility Antigens Class II, Listeria monocytogenes, Proteasome Endopeptidase Complex, T-Lymphocytes, Helper-Inducer, Transplantation, Homologous
Added March 20, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens.
Van Kaer L, Parekh VV, Wu L
(2011) Immunotherapy 3: 59-75
MeSH Terms: Animals, Antigen Presentation, Antigens, Autoimmune Diseases, Clinical Trials as Topic, Galactosylceramides, Glycolipids, Humans, Immunotherapy, Infections, Mice, Mice, Inbred C57BL, Natural Killer T-Cells, Neoplasms, Treatment Outcome
Added March 20, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M
(2010) Science 330: 1551-7
MeSH Terms: African Americans, Alleles, Amino Acids, Antigen Presentation, CD8-Positive T-Lymphocytes, Cohort Studies, Disease Progression, European Continental Ancestry Group, Genes, MHC Class I, Genome-Wide Association Study, HIV Antigens, HIV Infections, HIV Long-Term Survivors, HIV-1, HLA-A Antigens, HLA-B Antigens, HLA-C Antigens, Haplotypes, Hispanic Americans, Humans, Immunity, Innate, Logistic Models, Models, Molecular, Polymorphism, Single Nucleotide, Protein Conformation, Viral Load
Added March 13, 2015
0 Communities
1 Members
0 Resources
26 MeSH Terms
Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy.
Foster S, Duvall CL, Crownover EF, Hoffman AS, Stayton PS
(2010) Bioconjug Chem 21: 2205-12
MeSH Terms: Acrylates, Animals, Antigen Presentation, Antigens, CD8-Positive T-Lymphocytes, Cancer Vaccines, Cell Proliferation, Disease-Free Survival, Drug Delivery Systems, Endosomes, Female, Hydrogen-Ion Concentration, Immunoglobulin G, Lymphocyte Activation, Methacrylates, Mice, Mice, Inbred C57BL, Neoplasm Transplantation, Nylons, Ovalbumin, Polymers, Thymoma, Thymus Neoplasms, Treatment Outcome
Added March 14, 2018
0 Communities
1 Members
0 Resources
24 MeSH Terms
Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented.
Escande-Beillard N, Washburn L, Zekzer D, Wu ZP, Eitan S, Ivkovic S, Lu Y, Dang H, Middleton B, Bilousova TV, Yoshimura Y, Evans CJ, Joyce S, Tian J, Kaufman DL
(2010) J Immunol 184: 816-23
MeSH Terms: Alleles, Animals, Antigen Presentation, Autoantigens, Embryonic Stem Cells, Histocompatibility Antigens Class I, Immunity, Innate, Mice, Neurites, Neurons, Peptides, Retina
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.
Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S
(2009) EMBO J 28: 3579-90
MeSH Terms: Adaptation, Biological, Animals, Antigen Presentation, Antigens, CD1d, Antigens, Tumor-Associated, Carbohydrate, Cells, Cultured, Galactosylceramides, Ligands, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Models, Molecular, Natural Killer T-Cells, Receptors, Antigen, T-Cell, Receptors, Antigen, T-Cell, alpha-beta, Structure-Activity Relationship, T-Cell Antigen Receptor Specificity
Added May 19, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.
Florence WC, Bhat RK, Joyce S
(2008) Expert Rev Mol Med 10: e20
MeSH Terms: Animals, Antigen Presentation, Antigens, Antigens, CD1, Antigens, CD1d, Autoantigens, Autoimmune Diseases, Cell Membrane, Glycolipids, Humans, Immune System, Killer Cells, Natural, Models, Biological, Neoplasms, Phenotype, Receptors, Antigen, T-Cell
Added May 19, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Pillars article: antigen presentation: discovery of the peptide TAP.
Van Kaer L
(2008) J Immunol 180: 2723-4
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, History, 20th Century, Humans, Membrane Transport Proteins, T-Lymphocytes, Cytotoxic
Added December 10, 2013
0 Communities
1 Members
0 Resources
9 MeSH Terms