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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 21 to 30 of 59

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TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.
Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2011) Am J Physiol Lung Cell Mol Physiol 300: L887-97
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Cell Proliferation, Cells, Cultured, Disease Models, Animal, Epithelium, Fibroblasts, Fluorescent Antibody Technique, Lung Injury, Mice, Mice, Transgenic, Pneumonia, Protein Serine-Threonine Kinases, Pulmonary Alveoli, Pulmonary Fibrosis, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta, beta-Galactosidase
Added March 5, 2014
1 Communities
2 Members
0 Resources
22 MeSH Terms
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.
McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M
(2011) Arthritis Res Ther 13: R6
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Disease Models, Animal, Female, Fibroblasts, Fibrosis, Fluorescent Antibody Technique, Immunohistochemistry, Intramolecular Oxidoreductases, Male, Mice, Mice, Knockout, Prostaglandin-E Synthases, Scleroderma, Systemic
Added September 18, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Mechanisms of anthracycline cardiotoxicity and strategies to decrease cardiac damage.
Geisberg CA, Sawyer DB
(2010) Curr Hypertens Rep 12: 404-10
MeSH Terms: Adrenergic beta-Antagonists, Angiotensin-Converting Enzyme Inhibitors, Animals, Anthracyclines, Antibiotics, Antineoplastic, Antineoplastic Protocols, Cardiotonic Agents, Cardiotoxins, Cell Death, Heart Diseases, Humans, Models, Animal, Neoplasms, Oxidative Stress, Risk Factors, Sarcomeres, Time
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?
Sawyer DB, Peng X, Chen B, Pentassuglia L, Lim CC
(2010) Prog Cardiovasc Dis 53: 105-13
MeSH Terms: Animals, Anthracyclines, Antibiotics, Antineoplastic, Cell Death, Heart Diseases, Humans, Myocytes, Cardiac, Neoplasms, Receptor, ErbB-2, Sarcomeres, Signal Transduction
Added May 28, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis.
Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2010) Am J Physiol Lung Cell Mol Physiol 299: L442-52
MeSH Terms: Animals, Antibiotics, Antineoplastic, Apoptosis, Bleomycin, Bronchoalveolar Lavage Fluid, Cell Proliferation, Cells, Cultured, Disease Models, Animal, Epithelial Cells, Fibroblasts, Fluorescent Antibody Technique, Humans, Idiopathic Pulmonary Fibrosis, Immunoenzyme Techniques, In Situ Nick-End Labeling, Integrases, Intubation, Intratracheal, Mesoderm, Mice, Mice, Inbred C57BL, Mice, Transgenic, beta-Galactosidase
Added March 5, 2014
1 Communities
2 Members
0 Resources
22 MeSH Terms
Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells.
Liu Y, Li PK, Li C, Lin J
(2010) J Biol Chem 285: 27429-27439
MeSH Terms: Anthraquinones, Antibiotics, Antineoplastic, Antibodies, Apoptosis, Carcinoma, Hepatocellular, Cell Line, Tumor, Cell Survival, Doxorubicin, Drug Resistance, Neoplasm, Humans, Interleukin-6, Liver Neoplasms, Phosphorylation, STAT3 Transcription Factor, Signal Transduction, Sulfonamides
Added June 14, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent.
Ratliff BB, Ghaly T, Brudnicki P, Yasuda K, Rajdev M, Bank M, Mares J, Hatzopoulos AK, Goligorsky MS
(2010) Am J Physiol Renal Physiol 299: F178-86
MeSH Terms: Animals, Antibiotics, Antineoplastic, Cell Line, Cell Movement, Cell Proliferation, Cell Survival, Disease Models, Animal, Dose-Response Relationship, Drug, Doxorubicin, Embryonic Stem Cells, Endothelial Cells, Fibronectins, Hyaluronic Acid, Hydrogels, Ischemia, Kidney, Kidney Diseases, Mice, Mice, Inbred BALB C, Muscle, Skeletal, Neovascularization, Physiologic, Regional Blood Flow, Stem Cell Niche, Stem Cell Transplantation, Time Factors, Tissue Engineering, Tissue Scaffolds
Added November 18, 2010
1 Communities
1 Members
0 Resources
27 MeSH Terms
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
Demetri GD, Chawla SP, von Mehren M, Ritch P, Baker LH, Blay JY, Hande KR, Keohan ML, Samuels BL, Schuetze S, Lebedinsky C, Elsayed YA, Izquierdo MA, Gómez J, Park YC, Le Cesne A
(2009) J Clin Oncol 27: 4188-96
MeSH Terms: Adult, Aged, Aged, 80 and over, Anthracyclines, Antibiotics, Antineoplastic, Antineoplastic Agents, Alkylating, Australia, Dioxoles, Disease-Free Survival, Drug Administration Schedule, Drug Resistance, Neoplasm, Europe, Female, Humans, Ifosfamide, Infusions, Intravenous, Kaplan-Meier Estimate, Leiomyosarcoma, Liposarcoma, Male, Middle Aged, Neoplasm Staging, North America, Proportional Hazards Models, Risk Assessment, Tetrahydroisoquinolines, Time Factors, Trabectedin, Treatment Failure, Young Adult
Added March 20, 2014
0 Communities
1 Members
0 Resources
30 MeSH Terms
Distinct roles for basal and induced COX-2 in podocyte injury.
Cheng H, Fan X, Guan Y, Moeckel GW, Zent R, Harris RC
(2009) J Am Soc Nephrol 20: 1953-62
MeSH Terms: Albuminuria, Animals, Antibiotics, Antineoplastic, Apoptosis, Cell Adhesion, Cell Line, Transformed, Cell Survival, Cyclooxygenase 2, Dinoprostone, Doxorubicin, Glomerulonephritis, Male, Mice, Mice, Inbred Strains, Mice, Transgenic, Podocytes, Puromycin, RNA, Messenger, Receptors, Prostaglandin E, Receptors, Thromboxane, Thromboxanes
Added December 10, 2013
2 Communities
3 Members
0 Resources
21 MeSH Terms
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, Lawson WE
(2009) Am J Respir Crit Care Med 180: 657-65
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Cell Culture Techniques, Disease Models, Animal, Epithelial Cells, Epithelium, Fibroblasts, Mesoderm, Mice, Mice, Transgenic, Pulmonary Alveoli, Pulmonary Fibrosis
Added March 5, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms