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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 241 to 250 of 255

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Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway.
Martin KA, Schalm SS, Richardson C, Romanelli A, Keon KL, Blenis J
(2001) J Biol Chem 276: 7884-91
MeSH Terms: Cells, Cultured, Humans, Isoenzymes, Phosphatidylinositol 3-Kinases, Protein Kinase C, Ribosomal Protein S6 Kinases, cdc42 GTP-Binding Protein
Added September 10, 2013
0 Communities
2 Members
0 Resources
7 MeSH Terms
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.
Bakin AV, Tomlinson AK, Bhowmick NA, Moses HL, Arteaga CL
(2000) J Biol Chem 275: 36803-10
MeSH Terms: Breast Neoplasms, Cell Movement, DNA-Binding Proteins, Enzyme Activation, Female, Humans, Mesoderm, Phosphatidylinositol 3-Kinases, Signal Transduction, Smad2 Protein, Trans-Activators, Transforming Growth Factor beta, Tumor Cells, Cultured, rho GTP-Binding Proteins
Added February 17, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
IL-4-dependent induction of BCL-2 and BCL-X(L)IN activated T lymphocytes through a STAT6- and pi 3-kinase-independent pathway.
Aronica MA, Goenka S, Boothby M
(2000) Cytokine 12: 578-87
MeSH Terms: Androstadienes, Animals, Cell Division, Cell Line, Cell Survival, Crosses, Genetic, Enzyme Inhibitors, Genes, bcl-2, Interleukin-4, Lymphocyte Activation, Mice, Mice, Knockout, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-bcl-2, Receptors, Interleukin-4, Recombinant Proteins, STAT6 Transcription Factor, Signal Transduction, Sirolimus, T-Lymphocytes, Cytotoxic, Trans-Activators, Transcriptional Activation, Transfection, Wortmannin, bcl-X Protein
Added December 10, 2013
0 Communities
1 Members
0 Resources
25 MeSH Terms
Role of the alpha1 and alpha2 integrin cytoplasmic domains in cell morphology, motility and responsiveness to stimulation by the protein kinase C pathway.
Wang H, Gai Q, Yang X, Li Z, Linders B, Santoro SA, Zutter MM
(2000) Cell Adhes Commun 7: 281-97
MeSH Terms: Antigens, CD, Cell Adhesion, Cell Movement, Cell Size, Collagen, Cytoplasm, DNA, Complementary, Flow Cytometry, Gene Expression, Hematopoietic Stem Cells, Humans, Integrin alpha1, Integrin alpha2, Integrins, K562 Cells, MAP Kinase Signaling System, Phosphatidylinositol 3-Kinases, Protein Kinase C, Protein Structure, Tertiary, Receptors, Collagen, Recombinant Fusion Proteins
Added February 16, 2014
1 Communities
2 Members
0 Resources
21 MeSH Terms
NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK.
Baliga RR, Pimental DR, Zhao YY, Simmons WW, Marchionni MA, Sawyer DB, Kelly RA
(1999) Am J Physiol 277: H2026-37
MeSH Terms: Actins, Animals, Animals, Newborn, Atrial Natriuretic Factor, Cardiomegaly, Cells, Cultured, Enzyme Activation, Enzyme Inhibitors, Gene Expression, Heart Ventricles, Humans, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Myocardium, Neuregulin-1, Phosphatidylinositol 3-Kinases, Protein Precursors, Rats, Recombinant Proteins, Ribosomal Protein S6 Kinases, Sarcomeres
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
The role of phosphoinositide 3-kinase lipid products in cell function.
Rameh LE, Cantley LC
(1999) J Biol Chem 274: 8347-50
MeSH Terms: Eukaryotic Cells, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phosphorylation, Protein Kinases, Signal Transduction
Added November 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling.
Rameh LE, Rhee SG, Spokes K, Kazlauskas A, Cantley LC, Cantley LG
(1998) J Biol Chem 273: 23750-7
MeSH Terms: Androstadienes, Binding Sites, Calcium, Chromones, Enzyme Inhibitors, Humans, Isoenzymes, Kinetics, Morpholines, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phospholipase C gamma, Platelet-Derived Growth Factor, Receptors, Platelet-Derived Growth Factor, Recombinant Fusion Proteins, Signal Transduction, Transfection, Tumor Cells, Cultured, Type C Phospholipases, Wortmannin
Added November 26, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Disruption of IRS-2 causes type 2 diabetes in mice.
Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF
(1998) Nature 391: 900-4
MeSH Terms: Animals, Blood Glucose, Cloning, Molecular, Diabetes Mellitus, Type 2, Female, Gene Targeting, Humans, Insulin, Insulin Receptor Substrate Proteins, Insulin Resistance, Intracellular Signaling Peptides and Proteins, Islets of Langerhans, Liver, Male, Mice, Mice, Inbred C57BL, Muscle, Skeletal, Phosphatidylinositol 3-Kinases, Phosphoproteins, Phosphorylation, Receptor, Insulin, Recombination, Genetic, Signal Transduction
Added April 24, 2015
1 Communities
0 Members
0 Resources
23 MeSH Terms
Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate.
Klarlund JK, Rameh LE, Cantley LC, Buxton JM, Holik JJ, Sakelis C, Patki V, Corvera S, Czech MP
(1998) J Biol Chem 273: 1859-62
MeSH Terms: ADP-Ribosylation Factor 1, ADP-Ribosylation Factors, Animals, Binding Sites, Carrier Proteins, Catalysis, Cells, Cultured, GTP-Binding Proteins, Guanosine 5'-O-(3-Thiotriphosphate), Inositol Phosphates, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Receptors, Cytoplasmic and Nuclear, Recombinant Proteins, Spodoptera
Added November 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Hepatic expression of ErbB3 is repressed by insulin in a pathway sensitive to PI-3 kinase inhibitors.
Carver RS, Mathew PM, Russell WE
(1997) Endocrinology 138: 5195-201
MeSH Terms: Animals, Cells, Cultured, Cyclic AMP, Enzyme Activation, Enzyme Inhibitors, ErbB Receptors, Humans, Insulin, Intracellular Membranes, Liver, Male, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Protein Kinase C, Proto-Oncogene Proteins, Rats, Rats, Sprague-Dawley, Receptor, ErbB-3, Recombinant Proteins, Ribosomal Protein S6 Kinases
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms