An alternate promoter in the glucokinase gene is active in the pancreatic beta cell.
Magnuson MA, Shelton KD
(1989) J Biol Chem 264
: 15936-42MeSH Terms: Adenoma, Islet Cell, Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, Gene Amplification, Genes, Glucokinase, Insulinoma, Islets of Langerhans, Isoenzymes, Molecular Sequence Data, Pancreatic Neoplasms, Promoter Regions, Genetic, RNA Splicing, RNA, Messenger, Rats, Restriction Mapping, Sequence Homology, Nucleic Acid, Transcription, GeneticAdded February 23, 2011
20 MeSH Terms
Monoclonal antibodies as probes to the differentiated exocrine pancreas react to monoclonal islet tumor tissue.
Beck TC, Madsen OD
(1989) Exp Clin Endocrinol 93
: 255-60MeSH Terms: Adenoma, Islet Cell, Animals, Antibodies, Monoclonal, Female, Immunohistochemistry, Mice, Mice, Inbred BALB C, Pancreas, Pancreatic NeoplasmsAdded August 18, 2010
9 MeSH Terms
Expression of and response to growth regulatory peptides by two human pancreatic carcinoma cell lines.
Beauchamp RD, Lyons RM, Yang EY, Coffey RJ, Moses HL
(1990) Pancreas 5
: 369-80MeSH Terms: Adenocarcinoma, Cell Division, Fibroblast Growth Factors, Gene Expression, Humans, Insulin, Nucleic Acid Hybridization, Pancreatic Neoplasms, Platelet-Derived Growth Factor, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-sis, RNA, Messenger, Transcription, Genetic, Transforming Growth Factors, Tumor Cells, CulturedAdded February 17, 2014
15 MeSH Terms
Altered regulation of protein disulfide isomerase in cells resistant to the growth-inhibitory effects of transforming growth factor beta 1.
Sipes NJ, Miller DA, Bascom CC, Winkler JK, Matrisian LM, Moses HL
(1990) Cell Growth Differ 1
: 241-6MeSH Terms: Animals, Carcinoma, Cell Division, Cell Line, Transformed, Cell Transformation, Viral, DNA, Drug Resistance, Enzyme Induction, Humans, Isomerases, Keratinocytes, Kirsten murine sarcoma virus, Mice, Neoplasm Proteins, Pancreatic Neoplasms, Protein Disulfide-Isomerases, Protein Processing, Post-Translational, Proto-Oncogene Proteins c-myc, RNA, Messenger, Signal Transduction, Transforming Growth Factor beta, Tumor Cells, CulturedAdded February 17, 2014
22 MeSH Terms
Human carcinoid cell production of paracrine growth factors that can stimulate fibroblast and endothelial cell growth.
Beauchamp RD, Coffey RJ, Lyons RM, Perkett EA, Townsend CM, Moses HL
(1991) Cancer Res 51
: 5253-60MeSH Terms: Amino Acid Isomerases, Blotting, Northern, Carcinoid Tumor, Carrier Proteins, Cell Division, DNA, Dose-Response Relationship, Drug, Endothelium, Fibroblasts, Fibronectins, Growth Substances, Humans, Insulin, Pancreatic Neoplasms, Peptidylprolyl Isomerase, Procollagen, RNA, Messenger, Time Factors, Transcription, Genetic, Transforming Growth Factor alpha, Transforming Growth Factor betaAdded May 3, 2013
21 MeSH Terms
Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells.
Madsen OD, Nielsen JH, Michelsen B, Westermark P, Betsholtz C, Nishi M, Steiner DF
(1991) Mol Endocrinol 5
: 143-8MeSH Terms: Amyloid, Animals, Animals, Newborn, Cell Line, Cell Line, Transformed, Gene Expression Regulation, Glucagon, Glucagonoma, Growth Hormone, Humans, Immunohistochemistry, Insulin, Insulinoma, Islet Amyloid Polypeptide, Islets of Langerhans, Mice, Pancreatic Neoplasms, RNA, Messenger, Rats, Simian virus 40, TransfectionAdded August 18, 2010
21 MeSH Terms
Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells.
Parekh D, Ishizuka J, Townsend CM, Haber BE, Beauchamp RD, Rajaraman S, Karp G, Hsieh J, Thompson JC
(1991) Arch Surg 126
: 467-72MeSH Terms: 5-Hydroxytryptophan, Acetamides, Analysis of Variance, Butyrates, Butyric Acid, Carcinoid Tumor, Cell Division, Gastrinoma, Humans, Hydroxyindoleacetic Acid, Pancreatic Neoplasms, Serotonin, Transforming Growth Factor beta, Tumor Cells, CulturedAdded May 3, 2013
14 MeSH Terms
Inhibition of pancreatic adenocarcinoma cell growth by lovastatin.
Sumi S, Beauchamp RD, Townsend CM, Uchida T, Murakami M, Rajaraman S, Ishizuka J, Thompson JC
(1992) Gastroenterology 103
: 982-9MeSH Terms: Animals, Cell Division, Cell Survival, Cricetinae, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Humans, In Vitro Techniques, Lovastatin, Mevalonic Acid, Mice, Mice, Nude, Pancreatic Neoplasms, Time Factors, Transplantation, Heterologous, Tumor Cells, CulturedAdded May 3, 2013
16 MeSH Terms
Receptor-mediated autocrine growth-stimulatory effect of 5-hydroxytryptamine on cultured human pancreatic carcinoid cells.
Ishizuka J, Beauchamp RD, Townsend CM, Greeley GH, Thompson JC
(1992) J Cell Physiol 150
: 1-7MeSH Terms: 8-Bromo Cyclic Adenosine Monophosphate, Cell Division, Cyclic AMP, Cyclic GMP, Ergolines, Humans, Pancreatic Neoplasms, Pertussis Toxin, Phosphatidylinositols, Pindolol, Receptors, Serotonin, Second Messenger Systems, Serotonin, Serotonin Antagonists, Tumor Cells, Cultured, Virulence Factors, BordetellaAdded May 3, 2013
16 MeSH Terms
Glucagonoma syndrome in a 19-year-old woman.
Riddle MC, Golper TA, Fletcher WS, Ensinck JW, Smith PH
(1978) West J Med 129
: 68-72MeSH Terms: Adenoma, Islet Cell, Adult, Female, Glucagon, Humans, Neoplasm Metastasis, Pancreatic Neoplasms, Skin Manifestations, SyndromeAdded August 10, 2015
9 MeSH Terms