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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 191 to 200 of 202

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF.
Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH
(1987) Brain Res 415: 293-9
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 3,4-Dihydroxyphenylacetic Acid, Animals, Catecholamines, Chlorocebus aethiops, Corpus Striatum, Dopamine, Homovanillic Acid, Male, Methoxyhydroxyphenylglycol, Pyridines, Tegmentum Mesencephali
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism.
Sladek JR, Redmond DE, Collier TJ, Haber SN, Elsworth JD, Deutch AY, Roth RH
(1987) Prog Brain Res 71: 309-23
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Animals, Brain, Chlorocebus aethiops, Dopamine, Fetus, Neurons, Parkinson Disease, Parkinson Disease, Secondary, Pyridines
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum.
Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH
(1987) Life Sci 40: 193-202
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 3,4-Dihydroxyphenylacetic Acid, Animals, Caudate Nucleus, Chlorocebus aethiops, Corpus Striatum, Dopamine, Homovanillic Acid, Male, Neurotoxins, Norepinephrine, Pyridines, Substantia Nigra
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Deutch AY, Elsworth JD, Goldstein M, Fuxe K, Redmond DE, Sladek JR, Roth RH
(1986) Neurosci Lett 68: 51-6
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Animals, Chlorocebus aethiops, Dopamine, Histocytochemistry, Immunochemistry, Mesencephalon, Neurons, Neurotoxins, Pyridines
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Cytochrome P-450-catalyzed dehydrogenation of 1,4-dihydropyridines.
Guengerich FP, Böcker RH
(1988) J Biol Chem 263: 8168-75
MeSH Terms: Algorithms, Animals, Cytochrome P-450 Enzyme System, Dihydropyridines, Humans, Kinetics, Microsomes, Liver, Models, Chemical, Rats, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Reversal of parkinsonism by fetal nerve cell transplants in primate brain.
Sladek JR, Collier TJ, Haber SN, Deutch AY, Elsworth JD, Roth RH, Redmond DE
(1987) Ann N Y Acad Sci 495: 641-57
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Animals, Chlorocebus aethiops, Corpus Striatum, Fetus, Homovanillic Acid, Male, Motor Activity, Parkinson Disease, Pyridines, Substantia Nigra, Tyrosine 3-Monooxygenase
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine.
Redmond DE, Sladek JR, Roth RH, Collier TJ, Elsworth JD, Deutch AY, Haber S
(1986) Lancet 1: 1125-7
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Animals, Chlorocebus aethiops, Disease Models, Animal, Dopamine, Fetus, Histocytochemistry, Homovanillic Acid, Male, Neurons, Parkinson Disease, Secondary, Pyridines, Substantia Nigra, Tyrosine 3-Monooxygenase
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism.
Deutch AY, Rosin DL, Goldstein M, Roth RH
(1989) Exp Neurol 105: 1-9
MeSH Terms: Animals, Corpus Striatum, Dopamine, Immunohistochemistry, Male, Nerve Degeneration, Olivopontocerebellar Atrophies, Parkinson Disease, Pyridines, Rats, Rats, Inbred Strains, Spinocerebellar Degenerations, Substantia Nigra, Tyrosine 3-Monooxygenase
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids.
Guengerich FP, Kim DH
(1990) Carcinogenesis 11: 2275-9
MeSH Terms: Aflatoxins, Chamomile, Chromatography, High Pressure Liquid, Dihydropyridines, Felodipine, Flavanones, Flavins, Flavonoids, Gene Expression Regulation, Hesperidin, Humans, In Vitro Techniques, Kaempferols, Microsomes, Liver, Oils, Volatile, Plants, Medicinal, Quercetin, Transcriptional Activation
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation.
Deutch AY, Elsworth JD, Roth RH, Goldstein M, Deutsch AY
(1990) Brain Res 527: 96-102
MeSH Terms: Animals, Cerebellum, Corpus Striatum, Dopamine, Extrapyramidal Tracts, MPTP Poisoning, Male, Molecular Structure, Nerve Degeneration, Pyridines, Rats, Rats, Inbred Strains, Selegiline
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms