The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors.
Dey S, Curtis DJ, Jane SM, Brandt SJ
(2010) Mol Cell Biol 30
: 2181-92MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Cycle, Cell Differentiation, Cell Line, Cell Proliferation, Cell Survival, Cyclin-Dependent Kinase Inhibitor p16, DNA, GATA2 Transcription Factor, Gene Expression Regulation, Gene Knockout Techniques, Introns, Leukopoiesis, Mice, Mice, Knockout, Monocytes, Protein Binding, Proto-Oncogene Proteins, RNA, Messenger, Stem Cells, T-Cell Acute Lymphocytic Leukemia Protein 1, beta-GalactosidaseAdded March 5, 2014
23 MeSH Terms
p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.
Post SM, Quintás-Cardama A, Terzian T, Smith C, Eischen CM, Lozano G
(2010) Oncogene 29
: 1260-9MeSH Terms: Aging, Animals, Apoptosis, B-Lymphocytes, Cyclin-Dependent Kinase Inhibitor p16, Dromaiidae, Genes, p53, Lymphoma, Lymphoma, B-Cell, Mice, Proto-Oncogene Proteins c-myc, Tumor Suppressor Protein p53, beta-GalactosidaseAdded March 17, 2014
13 MeSH Terms
Autoimmune pancreatitis results from loss of TGFbeta signalling in S100A4-positive dendritic cells.
Boomershine CS, Chamberlain A, Kendall P, Afshar-Sharif AR, Huang H, Washington MK, Lawson WE, Thomas JW, Blackwell TS, Bhowmick NA
(2009) Gut 58
: 1267-74MeSH Terms: Adoptive Transfer, Animals, Autoantibodies, Autoimmune Diseases, Biomarkers, Cell Proliferation, Chimera, Dendritic Cells, Flow Cytometry, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, Models, Animal, Pancreatitis, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, S100 Calcium-Binding Protein A4, S100 Proteins, Signal Transduction, T-Lymphocytes, Transforming Growth Factor beta, beta-GalactosidaseAdded December 10, 2013
24 MeSH Terms
BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization.
Luppen CA, Chandler RL, Noh T, Mortlock DP, Frenkel B
(2008) Growth Factors 26
: 226-37MeSH Terms: 3T3 Cells, Alkaline Phosphatase, Animals, Bone Morphogenetic Protein 2, Bone Morphogenetic Protein 4, Calcification, Physiologic, Gene Expression, Genes, Reporter, Glucocorticoids, Humans, Luciferases, Mice, Osteoblasts, Recombinant Proteins, Signal Transduction, Transfection, beta-GalactosidaseAdded June 9, 2010
17 MeSH Terms
Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration.
Ho KJ, Bass CE, Kroemer AH, Ma C, Terwilliger E, Karp SJ
(2008) Am J Physiol Gastrointest Liver Physiol 295
: G412-9MeSH Terms: Animals, Cell Proliferation, Dependovirus, Gene Transfer Techniques, Genetic Vectors, Hepatocytes, Integrases, Liver Regeneration, Male, Mice, Mice, Transgenic, Recombination, Genetic, beta-GalactosidaseAdded May 22, 2014
13 MeSH Terms
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.
Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV
(2008) Dev Biol 314
: 406-17MeSH Terms: Animals, Blood Glucose, Embryonic Development, Gene Expression Regulation, Developmental, Glucose, Glucose Intolerance, Glucose Tolerance Test, Homeodomain Proteins, Homeostasis, Insulin-Secreting Cells, Islets of Langerhans, Mice, Mice, Knockout, Trans-Activators, beta-GalactosidaseAdded January 6, 2014
15 MeSH Terms
Long-range enhancers are required to maintain expression of the autoantigen islet-specific glucose-6-phosphatase catalytic subunit-related protein in adult mouse islets in vivo.
Wang Y, Flemming BP, Martin CC, Allen SR, Walters J, Oeser JK, Hutton JC, O'Brien RM
(2008) Diabetes 57
: 133-41MeSH Terms: Animals, Chromosomes, Artificial, Bacterial, Cloning, Molecular, Diabetes Mellitus, Type 1, Enhancer Elements, Genetic, Gene Expression Regulation, Genes, Reporter, Glucose-6-Phosphatase, Islets of Langerhans, Luciferases, Mice, Mice, Transgenic, Promoter Regions, Genetic, Proteins, Transfection, beta-GalactosidaseAdded August 13, 2010
16 MeSH Terms
A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development.
Lan Y, Wang Q, Ovitt CE, Jiang R
(2007) Genesis 45
: 618-24MeSH Terms: 3' Untranslated Regions, Animals, Cleft Palate, Enzyme Activation, Gene Expression Regulation, Developmental, Gene Targeting, Heterozygote, Homozygote, Integrases, Kidney, Kidney Glomerulus, Mesoderm, Mice, Mice, Transgenic, Morphogenesis, Mutagenesis, Insertional, Palate, Recombination, Genetic, Transcription Factors, beta-GalactosidaseAdded September 9, 2013
20 MeSH Terms
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter.
Chandler RL, Chandler KJ, McFarland KA, Mortlock DP
(2007) Mol Cell Biol 27
: 2934-51MeSH Terms: 3' Flanking Region, Animals, Base Pairing, Biomarkers, Bone Morphogenetic Protein 2, Bone Morphogenetic Proteins, Bone and Bones, Cell Differentiation, Embryo, Mammalian, Enhancer Elements, Genetic, Gene Expression Profiling, Gene Expression Regulation, Mice, Mice, Inbred C57BL, Osteoblasts, Promoter Regions, Genetic, RNA, Messenger, Sequence Deletion, Stem Cells, Tooth, Transcription, Genetic, Transforming Growth Factor beta, Transgenes, beta-GalactosidaseAdded August 13, 2010
24 MeSH Terms
Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.
Oda Y, Totsuka Y, Wakabayashi K, Guengerich FP, Shimada T
(2006) Mutagenesis 21
: 411-6MeSH Terms: Aniline Compounds, Arylamine N-Acetyltransferase, Cytochrome P-450 CYP1A2, DNA Damage, Humans, Indoles, Isoenzymes, Microsomes, Liver, Mutagenicity Tests, Mutagens, Phthalazines, Pyridines, Salmonella typhimurium, Toluidines, beta-GalactosidaseAdded March 26, 2014
15 MeSH Terms