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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 56

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RAF265 inhibits the growth of advanced human melanoma tumors.
Su Y, Vilgelm AE, Kelley MC, Hawkins OE, Liu Y, Boyd KL, Kantrow S, Splittgerber RC, Short SP, Sobolik T, Zaja-Milatovic S, Dahlman KB, Amiri KI, Jiang A, Lu P, Shyr Y, Stuart DD, Levy S, Sosman JA, Richmond A
(2012) Clin Cancer Res 18: 2184-98
MeSH Terms: Animals, Apoptosis, Base Sequence, Cell Cycle Proteins, Cell Proliferation, Cyclin D1, Extracellular Signal-Regulated MAP Kinases, Female, Gene Expression Profiling, Humans, Imidazoles, Ki-67 Antigen, MAP Kinase Signaling System, Male, Melanoma, Mice, Mice, Nude, Mutation, Oligonucleotide Array Sequence Analysis, Protein Kinase Inhibitors, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-kit, Proto-Oncogene Proteins p21(ras), Pyridines, Sequence Analysis, DNA, Tumor Cells, Cultured, Xenograft Model Antitumor Assays, bcl-X Protein
Added June 14, 2013
2 Communities
11 Members
0 Resources
30 MeSH Terms
IL-15 regulates homeostasis and terminal maturation of NKT cells.
Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S
(2011) J Immunol 187: 6335-45
MeSH Terms: Animals, Cell Differentiation, Cell Lineage, Cell Survival, Homeostasis, Interleukin-15, Liver, Lymphocyte Count, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Natural Killer T-Cells, Spleen, Thymus Gland, bcl-X Protein
Added December 10, 2013
0 Communities
4 Members
0 Resources
17 MeSH Terms
Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
Ma J, Matsusaka T, Yang HC, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I
(2011) Pediatr Res 70: 83-9
MeSH Terms: Actinin, Animals, Animals, Newborn, Apoptosis, Autocrine Communication, Caspase 3, Cells, Cultured, Desmin, Disease Models, Animal, Doxycycline, Glomerulonephritis, Humans, Intracellular Signaling Peptides and Proteins, Kidney Glomerulus, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microfilament Proteins, Podocytes, Puromycin Aminonucleoside, Response Elements, Vascular Endothelial Growth Factor A, bcl-2-Associated X Protein, bcl-X Protein
Added January 25, 2012
2 Communities
3 Members
0 Resources
25 MeSH Terms
Inhibition of Mdm2 sensitizes human retinal pigment epithelial cells to apoptosis.
Bhattacharya S, Ray RM, Chaum E, Johnson DA, Johnson LR
(2011) Invest Ophthalmol Vis Sci 52: 3368-80
MeSH Terms: Adult, Apoptosis, Blotting, Western, Caspase 3, Caspase 9, Cell Line, Cell Proliferation, DNA Fragmentation, Humans, Imidazoles, Piperazines, Protein Binding, Proto-Oncogene Proteins c-bcl-2, Proto-Oncogene Proteins c-mdm2, RNA, Small Interfering, Retinal Pigment Epithelium, Transfection, Tumor Suppressor Protein p53, bcl-X Protein
Added June 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
6-Mercaptopurine, monocytes, and atherosclerosis.
Linton MF, Fazio S
(2010) Arterioscler Thromb Vasc Biol 30: 1494-6
MeSH Terms: Animals, Apolipoprotein E3, Apoptosis, Atherosclerosis, Cell Adhesion, Chemokine CCL2, Chemotaxis, Humans, Immunosuppressive Agents, Inflammation Mediators, Integrin alpha4beta1, Macrophages, Mercaptopurine, Mice, Monocytes, Platelet Endothelial Cell Adhesion Molecule-1, Proto-Oncogene Proteins c-bcl-2, bcl-X Protein
Added May 27, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung.
Qian J, Zou Y, Rahman JS, Lu B, Massion PP
(2009) Mol Cancer Ther 8: 101-9
MeSH Terms: Adenocarcinoma, Apoptosis, Apoptosis Regulatory Proteins, Bcl-2-Like Protein 11, Cell Line, Tumor, Chromones, Humans, Lung Neoplasms, Membrane Proteins, Morpholines, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Protein Kinase Inhibitors, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-akt, Signal Transduction, Substrate Specificity, bcl-X Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes.
Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR
(2008) Neuroscience 157: 405-13
MeSH Terms: Analysis of Variance, Animals, Animals, Newborn, Apoptosis, Dexamethasone, Gene Expression, Glucocorticoids, Hair Cells, Auditory, Organ Culture Techniques, Organ of Corti, Proto-Oncogene Proteins c-bcl-2, Rats, Rats, Sprague-Dawley, Receptors, Tumor Necrosis Factor, Type I, Time Factors, Tumor Necrosis Factor-alpha, bcl-2-Associated X Protein, bcl-X Protein
Added April 18, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection.
Manicassamy S, Yin D, Zhang Z, Molinero LL, Alegre ML, Sun Z
(2008) J Immunol 181: 513-20
MeSH Terms: Animals, Antibodies, Monoclonal, Antigens, CD, CD40 Ligand, CTLA-4 Antigen, Cell Survival, Cells, Cultured, Female, Graft Rejection, Heart Transplantation, Homeodomain Proteins, Immunoglobulins, Isoenzymes, Lymphocyte Culture Test, Mixed, Mice, Mice, Knockout, Protein Kinase C, Protein Kinase C-theta, T-Lymphocytes, Transplantation, Homologous, bcl-X Protein
Added December 10, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.
Ghavami S, Kerkhoff C, Chazin WJ, Kadkhoda K, Xiao W, Zuse A, Hashemi M, Eshraghi M, Schulze-Osthoff K, Klonisch T, Los M
(2008) Biochim Biophys Acta 1783: 297-311
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Calgranulin A, Calgranulin B, Cell Death, Cell Line, Tumor, Down-Regulation, Dynamins, Fas-Associated Death Domain Protein, High-Temperature Requirement A Serine Peptidase 2, Humans, Intracellular Signaling Peptides and Proteins, Mice, Mitochondria, Mitochondrial Proteins, Protein Binding, Protein Processing, Post-Translational, Receptor for Advanced Glycation End Products, Receptors, Immunologic, Serine Endopeptidases, Signal Transduction, X-Linked Inhibitor of Apoptosis Protein, bcl-X Protein
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Heat shock factor 1 attenuates 4-Hydroxynonenal-mediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL.
Jacobs AT, Marnett LJ
(2007) J Biol Chem 282: 33412-33420
MeSH Terms: Aldehydes, Apoptosis, Cell Line, Tumor, Cell Nucleus, DNA Damage, DNA-Binding Proteins, Gene Silencing, HSP70 Heat-Shock Proteins, Heat Shock Transcription Factors, Humans, Lipid Peroxidation, Models, Biological, RNA, Small Interfering, Transcription Factors, Transfection, bcl-X Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms