LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E
(2008) Proc Natl Acad Sci U S A 105
: 8032-7MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Axin Protein, Cattle, Cell Extracts, Dishevelled Proteins, Embryo, Nonmammalian, Glycogen Synthase Kinase 3, Intracellular Space, Low Density Lipoprotein Receptor-Related Protein-6, Mice, Ovum, Phosphoproteins, Phosphorylation, Proteasome Endopeptidase Complex, Protein Processing, Post-Translational, Protein Structure, Tertiary, Receptors, LDL, Recombinant Proteins, Repressor Proteins, Signal Transduction, Thermodynamics, Ubiquitin, Wnt Proteins, Xenopus, Xenopus Proteins, beta CateninAdded March 5, 2014
27 MeSH Terms
Context-dependent activation or inhibition of Wnt-beta-catenin signaling by Kremen.
Cselenyi CS, Lee E
(2008) Sci Signal 1
: pe10MeSH Terms: Animals, Endocytosis, Frizzled Receptors, Intercellular Signaling Peptides and Proteins, Membrane Proteins, Protein Binding, Receptors, LDL, Signal Transduction, Wnt Proteins, Xenopus, Xenopus Proteins, beta CateninAdded March 5, 2014
12 MeSH Terms
Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.
Moore AC, Amann JM, Williams CS, Tahinci E, Farmer TE, Martinez JA, Yang G, Luce KS, Lee E, Hiebert SW
(2008) Mol Cell Biol 28
: 977-87MeSH Terms: Animals, COS Cells, Chlorocebus aethiops, Cricetinae, DNA-Binding Proteins, Humans, Intestine, Small, K562 Cells, Mice, Mice, Knockout, Nuclear Proteins, Protein Binding, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-myc, RUNX1 Translocation Partner 1 Protein, Repressor Proteins, TCF Transcription Factors, Transcription Factor 7-Like 2 Protein, Transcription Factors, Transcription, Genetic, Transfection, Xenopus Proteins, beta CateninAdded February 21, 2014
23 MeSH Terms
Xenopus Lefty requires proprotein cleavage but not N-linked glycosylation to inhibit nodal signaling.
Westmoreland JJ, Takahashi S, Wright CV
(2007) Dev Dyn 236
: 2050-61MeSH Terms: Animals, Binding Sites, Dihydropyridines, Embryo, Nonmammalian, Embryonic Induction, Glycosylation, Left-Right Determination Factors, Mesoderm, Oocytes, Protein Isoforms, Protein Processing, Post-Translational, Signal Transduction, Transforming Growth Factor beta, Xenopus, Xenopus ProteinsAdded June 11, 2010
15 MeSH Terms
Nonredundant functions of Kinesin-13s during meiotic spindle assembly.
Ohi R, Burbank K, Liu Q, Mitchison TJ
(2007) Curr Biol 17
: 953-9MeSH Terms: Animals, Cell Extracts, Kinesins, Models, Biological, Spindle Apparatus, Xenopus, Xenopus ProteinsAdded March 5, 2014
7 MeSH Terms
Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.
Morgan-Lappe SE, Tucker LA, Huang X, Zhang Q, Sarthy AV, Zakula D, Vernetti L, Schurdak M, Wang J, Fesik SW
(2007) Cancer Res 67
: 4390-8MeSH Terms: Cell Cycle, Cell Cycle Proteins, Cell Death, Cell Line, Tumor, Cell Survival, Gene Library, Genes, ras, Humans, Microtubule-Associated Proteins, Neoplasm Proteins, Neoplasms, Nuclear Proteins, Phosphoproteins, RNA Interference, RNA, Small Interfering, Stearoyl-CoA Desaturase, Xenopus Proteins, ran GTP-Binding ProteinAdded March 5, 2014
18 MeSH Terms
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas.
Jarikji ZH, Vanamala S, Beck CW, Wright CV, Leach SD, Horb ME
(2007) Dev Biol 304
: 786-99MeSH Terms: Animals, Animals, Genetically Modified, Duodenum, Gastric Mucosa, Herpes Simplex Virus Protein Vmw65, Liver, Pancreas, Recombinant Fusion Proteins, Signal Transduction, Stomach, Transcription Factors, Xenopus, Xenopus ProteinsAdded August 22, 2011
13 MeSH Terms
FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development.
Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS
(2006) Development 133
: 4827-38MeSH Terms: Animals, Body Patterning, Chordata, Embryonic Induction, Forkhead Transcription Factors, Gastrula, Gene Expression Regulation, Developmental, Homeodomain Proteins, Mesoderm, Nodal Protein, Organizers, Embryonic, Repressor Proteins, Signal Transduction, Transforming Growth Factor beta, Xenopus Proteins, Xenopus laevisAdded July 20, 2010
16 MeSH Terms
The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.
Montero-Balaguer M, Lang MR, Sachdev SW, Knappmeyer C, Stewart RA, De La Guardia A, Hatzopoulos AK, Knapik EW
(2006) Dev Dyn 235
: 3199-212MeSH Terms: Animals, Base Sequence, Body Patterning, Chondrogenesis, Chromosome Mapping, Embryonic Stem Cells, Forkhead Transcription Factors, Gene Expression Regulation, Developmental, In Situ Hybridization, Mutation, Neural Crest, Oligodeoxyribonucleotides, Antisense, Phenotype, Pigmentation, Proto-Oncogene Proteins c-mos, Xenopus Proteins, ZebrafishAdded November 18, 2010
17 MeSH Terms
Anteriorward shifting of asymmetric Xnr1 expression and contralateral communication in left-right specification in Xenopus.
Ohi Y, Wright CV
(2007) Dev Biol 301
: 447-63MeSH Terms: Animals, Body Patterning, Embryo, Nonmammalian, Gene Expression Regulation, Developmental, Mesoderm, Tail, Xenopus, Xenopus ProteinsAdded June 11, 2010
8 MeSH Terms