Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y
(2016) Genetics 203
: 269-81MeSH Terms: Adenomatous Polyposis Coli Protein, Animals, Axin Protein, Drosophila, Genotype, Mitosis, Protein Interaction Domains and Motifs, Protein Stability, Tankyrases, Wnt Proteins, Wnt Signaling Pathway, XenopusAdded February 13, 2017
12 MeSH Terms
Substrate modulus of 3D-printed scaffolds regulates the regenerative response in subcutaneous implants through the macrophage phenotype and Wnt signaling.
Guo R, Merkel AR, Sterling JA, Davidson JM, Guelcher SA
(2015) Biomaterials 73
: 85-95MeSH Terms: Animals, Cells, Cultured, Collagen, Down-Regulation, Fibroblasts, Humans, Intercellular Signaling Peptides and Proteins, Kinetics, Macrophages, Male, Neovascularization, Pathologic, Phenotype, Porosity, Pressure, Printing, Three-Dimensional, Rats, Rats, Sprague-Dawley, Regeneration, Tissue Engineering, Tissue Scaffolds, Wnt Proteins, Wnt Signaling Pathway, Wound Healing, beta CateninAdded February 23, 2016
24 MeSH Terms
Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis.
Paik DT, Rai M, Ryzhov S, Sanders LN, Aisagbonhi O, Funke MJ, Feoktistov I, Hatzopoulos AK
(2015) Circ Res 117
: 804-16MeSH Terms: Angiopoietin-1, Animals, Arterioles, Blood Vessels, Blotting, Western, Cell Line, Cell Proliferation, Cells, Cultured, Endothelial Cells, Fibrosis, Gene Expression, Humans, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Confocal, Muscle, Smooth, Vascular, Myocardium, Myocytes, Cardiac, Myocytes, Smooth Muscle, Myofibroblasts, NF-kappa B, Proto-Oncogene Proteins, Reverse Transcriptase Polymerase Chain Reaction, Vascular Endothelial Growth Factor Receptor-2, Wnt ProteinsAdded February 23, 2016
25 MeSH Terms
The Interplay between Wnt Mediated Expansion and Negative Regulation of Growth Promotes Robust Intestinal Crypt Structure and Homeostasis.
Du H, Nie Q, Holmes WR
(2015) PLoS Comput Biol 11
: e1004285MeSH Terms: Animals, Cell Movement, Computational Biology, Homeostasis, Intestinal Mucosa, Mice, Models, Biological, Stem Cells, Wnt Proteins, Wnt Signaling PathwayAdded February 26, 2016
10 MeSH Terms
Inhibition of Wnt/β-catenin pathway promotes regenerative repair of cutaneous and cartilage injury.
Bastakoty D, Saraswati S, Cates J, Lee E, Nanney LB, Young PP
(2015) FASEB J 29
: 4881-92MeSH Terms: Animals, Cartilage, Hair Follicle, Mice, Mice, Inbred C57BL, Regeneration, Skin, Wnt Proteins, Wound Healing, beta CateninAdded November 2, 2015
10 MeSH Terms
Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm.
Lippmann ES, Williams CE, Ruhl DA, Estevez-Silva MC, Chapman ER, Coon JJ, Ashton RS
(2015) Stem Cell Reports 4
: 632-44MeSH Terms: Fibroblast Growth Factors, Gene Expression Regulation, Developmental, Homeodomain Proteins, Humans, Neural Plate, Organ Specificity, Pluripotent Stem Cells, Signal Transduction, Stem Cells, Transcriptional Activation, Transcriptome, Tretinoin, Wnt Proteins, beta CateninAdded August 19, 2015
14 MeSH Terms
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.
Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD
(2015) J Invest Dermatol 135
: 2093-2101MeSH Terms: Animals, Child, DNA, Disease Models, Animal, Female, Humans, MAP Kinase Kinase Kinases, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Monomeric GTP-Binding Proteins, Mutation, Nevus, Pigmented, Sequence Analysis, DNA, Signal Transduction, Skin Neoplasms, Wnt ProteinsAdded May 19, 2015
18 MeSH Terms
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Bankhead EJ, Colasanto MP, Dyorich KM, Jamrich M, Murtaugh LC, Fuhrmann S
(2015) Am J Pathol 185
: 197-213MeSH Terms: Acyltransferases, Alleles, Animals, Disease Models, Animal, Eye, Female, Focal Dermal Hypoplasia, Gene Expression Regulation, Developmental, Genotype, Glycoproteins, Hemizygote, In Situ Hybridization, Ligands, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Mutation, Recombination, Genetic, Retinal Pigment Epithelium, Wnt ProteinsAdded November 19, 2015
21 MeSH Terms
Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia.
Valkenburg KC, Yu X, De Marzo AM, Spiering TJ, Matusik RJ, Williams BO
(2014) Prostate 74
: 1506-20MeSH Terms: Adenomatous Polyposis Coli Protein, Animals, Castration, Enzyme-Linked Immunosorbent Assay, Epithelial Cells, Immunohistochemistry, Male, Mice, Prostate, Prostatic Intraepithelial Neoplasia, Prostatic Neoplasms, Reverse Transcriptase Polymerase Chain Reaction, Tamoxifen, Wnt Proteins, Wnt Signaling Pathway, beta CateninAdded January 20, 2015
16 MeSH Terms
Progress made in the use of animal models for the study of high-risk, nonmuscle invasive bladder cancer.
Lin-Tsai O, Taylor JA, Clark PE, Adam RM, Wu XR, DeGraff DJ
(2014) Curr Opin Urol 24
: 512-6MeSH Terms: Animals, Carcinoma, Transitional Cell, Disease Models, Animal, Female, Hedgehog Proteins, Male, Mice, Mice, Transgenic, Risk Factors, Sex Factors, Signal Transduction, Tumor Microenvironment, Urinary Bladder Neoplasms, Wnt Proteins, beta CateninAdded February 12, 2015
15 MeSH Terms