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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 396

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Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R
(2017) Diabetes 66: 2830-2839
MeSH Terms: Animals, Cell Proliferation, Gene Expression Regulation, Homeodomain Proteins, Insulin-Secreting Cells, Male, Mice, Mice, Knockout, Oxidative Phosphorylation, Trans-Activators, Weaning
Added August 1, 2017
2 Communities
2 Members
0 Resources
11 MeSH Terms
The major miR-31 target genes STK40 and LATS2 and their implications in the regulation of keratinocyte growth and hair differentiation.
Luan L, Shi J, Yu Z, Andl T
(2017) Exp Dermatol 26: 497-504
MeSH Terms: 3' Untranslated Regions, Adaptor Proteins, Signal Transducing, Animals, Apoptosis, Carcinoma, Basal Cell, Cell Differentiation, Cell Line, Tumor, Cell Proliferation, Cell Survival, Hair Follicle, Homeodomain Proteins, Humans, Intracellular Signaling Peptides and Proteins, Keratinocytes, Mice, Mice, Transgenic, MicroRNAs, Protein-Serine-Threonine Kinases, Skin, Skin Neoplasms, Trans-Activators, Transcription Factors, Tumor Suppressor Proteins
Added June 21, 2017
1 Communities
0 Members
0 Resources
23 MeSH Terms
Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
Fishbein L, Leshchiner I, Walter V, Danilova L, Robertson AG, Johnson AR, Lichtenberg TM, Murray BA, Ghayee HK, Else T, Ling S, Jefferys SR, de Cubas AA, Wenz B, Korpershoek E, Amelio AL, Makowski L, Rathmell WK, Gimenez-Roqueplo AP, Giordano TJ, Asa SL, Tischler AS, Cancer Genome Atlas Research Network, Pacak K, Nathanson KL, Wilkerson MD
(2017) Cancer Cell 31: 181-193
MeSH Terms: Adult, Aged, Aged, 80 and over, DNA-Binding Proteins, Female, Gene Fusion, Humans, Male, Middle Aged, Mutation, Nuclear Proteins, Paraganglioma, Pheochromocytoma, Pol1 Transcription Initiation Complex Proteins, Proto-Oncogene Proteins c-ret, RNA-Binding Proteins, Trans-Activators, Transcription Factors
Added October 30, 2019
0 Communities
1 Members
0 Resources
18 MeSH Terms
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC
(2016) Genes Dev 30: 2669-2683
MeSH Terms: Acinar Cells, Animals, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, Gene Deletion, Gene Expression Regulation, Neoplastic, Homeodomain Proteins, Humans, Mice, Pancreatic Neoplasms, Tissue Array Analysis, Trans-Activators, Tumor Cells, Cultured
Added February 7, 2017
1 Communities
1 Members
0 Resources
13 MeSH Terms
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Yang YP, Magnuson MA, Stein R, Wright CV
(2017) Development 144: 248-257
MeSH Terms: Animals, Binding Sites, Cell Differentiation, Embryo, Mammalian, Enhancer Elements, Genetic, Gene Expression Regulation, Developmental, Homeodomain Proteins, Insulin-Secreting Cells, Islets of Langerhans, Mammals, Mice, Mice, Transgenic, Organogenesis, Species Specificity, Trans-Activators
Added December 29, 2016
2 Communities
3 Members
0 Resources
15 MeSH Terms
Impact of Pdx1-associated chromatin modifiers on islet β-cells.
Spaeth JM, Walker EM, Stein R
(2016) Diabetes Obes Metab 18 Suppl 1: 123-7
MeSH Terms: Animals, Chromatin Assembly and Disassembly, DNA Methylation, Diabetes Mellitus, Type 2, Gene Expression Regulation, Histone Code, Homeodomain Proteins, Humans, Insulin-Secreting Cells, Mice, Nucleosomes, Trans-Activators
Added September 19, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.
Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY
(2016) J Clin Invest 126: 3313-35
MeSH Terms: Adolescent, Adult, Aged, Animals, Child, Collagen, Endothelial Cells, Extracellular Matrix, Female, Glutamic Acid, Humans, Hypertension, Pulmonary, Infant, Intracellular Signaling Peptides and Proteins, Male, Mechanotransduction, Cellular, Middle Aged, Myocytes, Smooth Muscle, Phosphoproteins, Rats, Rats, Sprague-Dawley, Trans-Activators, Transcription Factors, Vascular Stiffness, Young Adult
Added September 16, 2016
0 Communities
1 Members
0 Resources
25 MeSH Terms
Characterization of Key Helicobacter pylori Regulators Identifies a Role for ArsRS in Biofilm Formation.
Servetas SL, Carpenter BM, Haley KP, Gilbreath JJ, Gaddy JA, Merrell DS
(2016) J Bacteriol 198: 2536-48
MeSH Terms: Bacterial Proteins, Biofilms, Gene Expression Regulation, Bacterial, Helicobacter pylori, Trans-Activators
Added April 26, 2017
0 Communities
1 Members
0 Resources
5 MeSH Terms
Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis.
Hendrix AS, Spoonmore TJ, Wilde AD, Putnam NE, Hammer ND, Snyder DJ, Guelcher SA, Skaar EP, Cassat JE
(2016) Antimicrob Agents Chemother 60: 5322-30
MeSH Terms: Animals, Anti-Bacterial Agents, Anti-Inflammatory Agents, Non-Steroidal, Bacterial Proteins, Bone Density Conservation Agents, Cell Survival, Delayed-Action Preparations, Diflunisal, Drug Repositioning, Female, Gene Expression, Humans, Mice, Mice, Inbred C57BL, Osteoblasts, Osteomyelitis, Primary Cell Culture, Staphylococcal Infections, Staphylococcus aureus, Trans-Activators, Treatment Outcome
Added April 8, 2017
0 Communities
3 Members
0 Resources
21 MeSH Terms
Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M
(2016) Cell Rep 15: 2637-2650
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Count, Cell Differentiation, Embryo, Mammalian, Gene Dosage, Gene Expression Regulation, Developmental, Gene Ontology, Gene Regulatory Networks, Glucose, Hepatocyte Nuclear Factor 6, Heterozygote, Homeodomain Proteins, Homeostasis, Insulin-Secreting Cells, Mice, Multigene Family, Nerve Tissue Proteins, Stem Cells, Trans-Activators, Weaning
Added July 5, 2016
1 Communities
2 Members
0 Resources
21 MeSH Terms