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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 66

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Crystallographic studies of chemically modified nucleic acids: a backward glance.
Egli M, Pallan PS
(2010) Chem Biodivers 7: 60-89
MeSH Terms: Base Pairing, Bridged Bicyclo Compounds, Carbohydrates, Crystallography, X-Ray, Molecular Conformation, Nucleic Acids, Nucleotides, Sulfhydryl Compounds
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Cysteine-based regulation of the CUL3 adaptor protein Keap1.
Sekhar KR, Rachakonda G, Freeman ML
(2010) Toxicol Appl Pharmacol 244: 21-6
MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Motifs, Animals, Cullin Proteins, Cysteine, Cytoskeletal Proteins, Gene Expression Regulation, Humans, Intracellular Signaling Peptides and Proteins, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, Oxidation-Reduction, Proteasome Endopeptidase Complex, Protein Processing, Post-Translational, Protein Structure, Tertiary, Structure-Activity Relationship, Sulfhydryl Compounds, Transcriptional Activation, Ubiquitination
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase.
Wadington MC, Ladner JE, Stourman NV, Harp JM, Armstrong RN
(2009) Biochemistry 48: 6559-61
MeSH Terms: Binding Sites, Disulfides, Escherichia coli, Escherichia coli Proteins, Fluorescence, Glutathione Disulfide, Glutathione Transferase, Kinetics, Ligands, Models, Molecular, Mutant Proteins, Oxidoreductases, Protein Multimerization, Protein Structure, Secondary, Static Electricity, Substrate Specificity, Sulfhydryl Compounds, Temperature, Titrimetry
Added January 30, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Pallan PS, Prakash TP, Li F, Eoff RL, Manoharan M, Egli M
(2009) Chem Commun (Camb) : 2017-9
MeSH Terms: Crystallography, X-Ray, DNA, Nucleic Acid Conformation, RNA, Sulfhydryl Compounds, Uridine
Added March 7, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Transporter-mediated protection against thiopurine-induced hematopoietic toxicity.
Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, Du W, Boyd K, Cheok M, Nakauchi H, Marzolini C, Kim RB, Poonkuzhali B, Schuetz E, Evans W, Relling M, Schuetz JD
(2008) Cancer Res 68: 4983-9
MeSH Terms: Alleles, Animals, Cell Membrane, Cells, Cultured, Cytoprotection, Drug Resistance, Neoplasm, Hematologic Diseases, Hematopoiesis, Humans, Leukemia, Myeloid, Acute, Membrane Transport Proteins, Mercaptopurine, Mice, Mice, Knockout, Models, Biological, Multidrug Resistance-Associated Proteins, Polymorphism, Single Nucleotide, Purines, Sulfhydryl Compounds, Survival Analysis, Tissue Distribution
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Mitochondrial protein targets of thiol-reactive electrophiles.
Wong HL, Liebler DC
(2008) Chem Res Toxicol 21: 796-804
MeSH Terms: Apoptosis, Biotin, Cell Line, Humans, Mitochondrial Proteins, Sulfhydryl Compounds
Added March 20, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Using 3'-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIalpha.
Deweese JE, Burgin AB, Osheroff N
(2008) Biochemistry 47: 4129-40
MeSH Terms: Antigens, Neoplasm, Base Sequence, DNA, DNA Primers, DNA Topoisomerases, Type II, DNA-Binding Proteins, Humans, Hydrolysis, Kinetics, Organophosphorus Compounds, Sulfhydryl Compounds
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produce DNA-protein cross-links but not mutations.
Loecken EM, Guengerich FP
(2008) Chem Res Toxicol 21: 453-8
MeSH Terms: Cell Survival, Cross-Linking Reagents, DNA, Environmental Pollutants, Epoxy Compounds, Escherichia coli, Ethylene Dibromide, Glyceraldehyde-3-Phosphate Dehydrogenases, Humans, Mutagens, Mutation, O(6)-Methylguanine-DNA Methyltransferase, Recombinant Proteins, Sulfhydryl Compounds
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Mitochondria in multiple sclerosis.
Ghafourifar P, Mousavizadeh K, Parihar MS, Nazarewicz RR, Parihar A, Zenebe WJ
(2008) Front Biosci 13: 3116-26
MeSH Terms: Animals, Apoptosis, DNA Damage, Encephalomyelitis, Autoimmune, Experimental, Humans, Mitochondria, Models, Biological, Multiple Sclerosis, Nitric Oxide, Peroxynitrous Acid, Reactive Nitrogen Species, Reactive Oxygen Species, Sulfhydryl Compounds
Added June 9, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Characterization of natural antimony resistance in Leishmania donovani isolates.
Mittal MK, Rai S, Ashutosh , Ravinder , Gupta S, Sundar S, Goyal N
(2007) Am J Trop Med Hyg 76: 681-8
MeSH Terms: Animals, Antimony, Antiprotozoal Agents, Buthionine Sulfoximine, Cells, Cultured, Drug Resistance, Gene Expression Regulation, Humans, Leishmania donovani, Leishmaniasis, Visceral, Sulfhydryl Compounds
Added July 10, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms