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Results: 11 to 18 of 18

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Novel properties of P450s in Streptomyces coelicolor.
Zhao B, Waterman MR
(2007) Drug Metab Rev 39: 343-52
MeSH Terms: Cytochrome P-450 Enzyme System, Heme, Models, Molecular, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
4 MeSH Terms
Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Zhao B, Lamb DC, Lei L, Kelly SL, Yuan H, Hachey DL, Waterman MR
(2007) Biochemistry 46: 8725-33
MeSH Terms: Bacterial Proteins, Binding Sites, Carbon-Carbon Double Bond Isomerases, Crystallography, X-Ray, Cytochrome P-450 Enzyme System, Dimerization, Models, Molecular, Naphthoquinones, Oxidation-Reduction, Pigments, Biological, Protein Conformation, Streptomyces coelicolor, Substrate Specificity
Added March 20, 2014
0 Communities
2 Members
0 Resources
13 MeSH Terms
Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2).
Chun YJ, Shimada T, Sanchez-Ponce R, Martin MV, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC, Guengerich FP
(2007) J Biol Chem 282: 17486-500
MeSH Terms: Bacterial Proteins, Cytochrome P-450 Enzyme System, Deuterium, Electron Transport, Escherichia coli, Humans, Hydroxylation, Iron-Sulfur Proteins, Lauric Acids, Molecular Structure, Oleic Acid, Oxidation-Reduction, Recombinant Proteins, Streptomyces coelicolor
Added March 5, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine.
Rupasinghe S, Schuler MA, Kagawa N, Yuan H, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC
(2006) FEBS Lett 580: 6338-42
MeSH Terms: Amino Acid Motifs, Bacterial Proteins, Cysteine, Cytochrome P-450 Enzyme System, Heme, Models, Molecular, Mutagenesis, Site-Directed, Protein Structure, Quaternary, Spectrophotometry, Ultraviolet, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Understanding electron transport systems of Streptomyces cytochrome P450.
Chun YJ, Shimada T, Waterman MR, Guengerich FP
(2006) Biochem Soc Trans 34: 1183-5
MeSH Terms: Bacterial Proteins, Catalysis, Cytochrome P-450 Enzyme System, Electron Transport, Spectrophotometry, Streptomyces, Streptomyces coelicolor
Added March 5, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms
Exploiting Streptomyces coelicolor A3(2) P450s as a model for application in drug discovery.
Lamb DC, Guengerich FP, Kelly SL, Waterman MR
(2006) Expert Opin Drug Metab Toxicol 2: 27-40
MeSH Terms: Animals, Bacterial Proteins, Cytochrome P-450 Enzyme System, Drug Delivery Systems, Drug Discovery, Humans, Models, Chemical, Streptomyces coelicolor
Added March 5, 2014
0 Communities
2 Members
0 Resources
8 MeSH Terms
Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2).
Zhao B, Waterman MR, Isin EM, Sundaramoorthy M, Podust LM
(2006) Biochemistry 45: 7493-500
MeSH Terms: Binding Sites, Crystallization, Cytochrome P-450 Enzyme Inhibitors, Escherichia coli, Hydrogen Bonding, Imidazoles, Kinetics, Ligands, Malonates, Mixed Function Oxygenases, Models, Molecular, Naphthoquinones, Protein Conformation, Protein Structure, Secondary, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2.
Zhao B, Guengerich FP, Bellamine A, Lamb DC, Izumikawa M, Lei L, Podust LM, Sundaramoorthy M, Kalaitzis JA, Reddy LM, Kelly SL, Moore BS, Stec D, Voehler M, Falck JR, Shimada T, Waterman MR
(2005) J Biol Chem 280: 11599-607
MeSH Terms: Crystallization, Cytochrome P-450 Enzyme System, Dimerization, Naphthoquinones, Oxidation-Reduction, Protein Conformation, Streptomyces coelicolor
Added March 5, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms