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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 77

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Na+ channel function, regulation, structure, trafficking and sequestration.
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM
(2015) J Physiol 593: 1347-60
MeSH Terms: Action Potentials, Amino Acid Sequence, Animals, Congresses as Topic, Humans, Molecular Sequence Data, Myocytes, Cardiac, Protein Transport, Sodium Channel Blockers, Sodium Channels
Added March 11, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.
Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA
(2015) Hypertension 65: 569-76
MeSH Terms: Angiotensin II, Animals, Biological Transport, Blood Pressure, Disease Models, Animal, Epithelial Sodium Channels, Genotype, Hypertension, Interferon-gamma, Interleukin-17, Kidney Tubules, Proximal, Mice, Mice, Inbred C57BL, Mice, Knockout, Sodium, Sodium Chloride Symporters, Sodium-Hydrogen Exchanger 3, Sodium-Hydrogen Exchangers, Solute Carrier Family 12, Member 1
Added March 31, 2015
2 Communities
2 Members
0 Resources
19 MeSH Terms
The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
Capdevila JH, Pidkovka N, Mei S, Gong Y, Falck JR, Imig JD, Harris RC, Wang W
(2014) J Biol Chem 289: 4377-86
MeSH Terms: Animals, Blood Pressure, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Epithelial Sodium Channels, Humans, Hypertension, Kidney, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 3, Phosphorylation, Sodium Chloride, Dietary
Added January 28, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms
Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels.
Kahlig KM, Hirakawa R, Liu L, George AL, Belardinelli L, Rajamani S
(2014) Mol Pharmacol 85: 162-74
MeSH Terms: Acetanilides, Action Potentials, Animals, Anticonvulsants, Cells, Cultured, Computer Simulation, Epilepsy, Hippocampus, Humans, Markov Chains, N-Methylaspartate, NAV1.1 Voltage-Gated Sodium Channel, NAV1.2 Voltage-Gated Sodium Channel, Neurons, Patch-Clamp Techniques, Piperazines, Protein Binding, Protein Conformation, Ranolazine, Rats, Voltage-Gated Sodium Channels
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Novel SCN3A variants associated with focal epilepsy in children.
Vanoye CG, Gurnett CA, Holland KD, George AL, Kearney JA
(2014) Neurobiol Dis 62: 313-22
MeSH Terms: Cells, Cultured, Child, Child, Preschool, Epilepsies, Partial, Female, Genetic Testing, HEK293 Cells, Humans, Male, Mutation, Missense, NAV1.3 Voltage-Gated Sodium Channel, Sodium Channels
Added March 7, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.
Aistrup GL, Gupta DK, Kelly JE, O'Toole MJ, Nahhas A, Chirayil N, Misener S, Beussink L, Singh N, Ng J, Reddy M, Mongkolrattanothai T, El-Bizri N, Rajamani S, Shryock JC, Belardinelli L, Shah SJ, Wasserstrom JA
(2013) Am J Physiol Heart Circ Physiol 305: H1068-79
MeSH Terms: Acetanilides, Animals, Calcium Channels, L-Type, Calcium Signaling, Disease Models, Animal, Disease Progression, Dose-Response Relationship, Drug, Heart Failure, Hypertension, Hypertrophy, Left Ventricular, Male, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Piperazines, Ranolazine, Rats, Rats, Inbred SHR, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Sodium, Sodium Channel Blockers, Sodium Channels, Sodium-Calcium Exchanger, Time Factors, Ultrasonography
Added February 28, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R
(2013) Nat Genet 45: 1044-9
MeSH Terms: Alleles, Animals, Basic Helix-Loop-Helix Transcription Factors, Brugada Syndrome, Case-Control Studies, Chromosomes, Human, Pair 3, Chromosomes, Human, Pair 6, Death, Sudden, Cardiac, Female, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Humans, Male, Mice, Mice, Knockout, NAV1.5 Voltage-Gated Sodium Channel, NAV1.8 Voltage-Gated Sodium Channel, Odds Ratio, Polymorphism, Single Nucleotide, Repressor Proteins, Sodium Channels
Added March 7, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism.
Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM
(2013) Am J Physiol Renal Physiol 304: F1390-7
MeSH Terms: Absorption, Aldosterone, Amiloride, Angiotensin II, Animals, Anion Transport Proteins, Chloride-Bicarbonate Antiporters, Chlorides, Epithelial Sodium Channels, Female, In Vitro Techniques, Kidney Tubules, Collecting, Male, Mice, Mice, Knockout, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Donors, Nitric Oxide Synthase, Sodium, Sulfate Transporters
Added March 31, 2015
1 Communities
2 Members
0 Resources
21 MeSH Terms
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility.
Du P, O'Grady G, Gao J, Sathar S, Cheng LK
(2013) Wiley Interdiscip Rev Syst Biol Med 5: 481-93
MeSH Terms: Algorithms, Humans, Hydrodynamics, Interstitial Cells of Cajal, Models, Biological, Myocytes, Smooth Muscle, Sodium Channels, Stomach
Added April 26, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.
Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH
(2013) J Biol Chem 288: 5223-31
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antihypertensive Agents, Cetuximab, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Epidermal Growth Factor, Epithelial Sodium Channels, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Humans, Hypertension, Kidney, Male, Mice, Models, Biological, Phosphorylation
Added August 19, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms