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Results: 11 to 20 of 160

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Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, Chen Y, Normandin E, Cantor E, Chen RE, Doria-Rose NA, Zhang Y, Shi W, Kong WP, Choe M, Henry AR, Laboune F, Georgiev IS, Huang PY, Jain S, McGuire AT, Georgeson E, Menis S, Douek DC, Schief WR, Stamatatos L, Kwong PD, Shapiro L, Haynes BF, Mascola JR, Alt FW
(2016) Cell 166: 1471-1484.e18
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, B-Lymphocytes, Broadly Neutralizing Antibodies, Cell Line, Disease Models, Animal, Gene Expression Regulation, HIV Antibodies, HIV-1, Immunization, Immunoglobulin Heavy Chains, Inhibitory Concentration 50, Mice, Precursor Cells, B-Lymphoid, Sequence Deletion, T-Lymphocytes
Added May 3, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
A Novel Saccharomyces cerevisiae FG Nucleoporin Mutant Collection for Use in Nuclear Pore Complex Functional Experiments.
Adams RL, Terry LJ, Wente SR
(2015) G3 (Bethesda) 6: 51-8
MeSH Terms: Gene Expression, Genetic Association Studies, Mutation, Nuclear Pore Complex Proteins, Phenotype, Plasmids, Protein Interaction Domains and Motifs, Saccharomyces cerevisiae, Sequence Deletion
Added February 15, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.
Heuermann RJ, Jaramillo TC, Ying SW, Suter BA, Lyman KA, Han Y, Lewis AS, Hampton TG, Shepherd GMG, Goldstein PA, Chetkovich DM
(2016) Neurobiol Dis 85: 81-92
MeSH Terms: Animals, Blotting, Western, Cerebral Cortex, Disease Models, Animal, Electrocardiography, Electrocorticography, Electrodes, Implanted, Epilepsy, Absence, Immunohistochemistry, Male, Membrane Potentials, Membrane Proteins, Mice, Knockout, Motor Activity, Neurons, Patch-Clamp Techniques, Peroxins, Rotarod Performance Test, Sequence Deletion, Thalamus, Tissue Culture Techniques
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Varshney GK, Pei W, LaFave MC, Idol J, Xu L, Gallardo V, Carrington B, Bishop K, Jones M, Li M, Harper U, Huang SC, Prakash A, Chen W, Sood R, Ledin J, Burgess SM
(2015) Genome Res 25: 1030-42
MeSH Terms: Alleles, Animals, CRISPR-Cas Systems, Gene Knockout Techniques, Gene Targeting, Genome-Wide Association Study, Genomics, Germ Cells, High-Throughput Screening Assays, Humans, Mutagenesis, Phenotype, Quantitative Trait Loci, RNA, Guide, Sequence Deletion, Zebrafish
Added July 23, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, Essigmann JM
(2015) Nucleic Acids Res 43: 5489-500
MeSH Terms: DNA Adducts, DNA Damage, DNA Polymerase beta, DNA Repair, DNA Repair Enzymes, Dioxygenases, Guanine, High-Throughput Nucleotide Sequencing, Mutagenesis, Mutation, Sequence Analysis, DNA, Sequence Deletion
Added January 7, 2016
0 Communities
3 Members
0 Resources
12 MeSH Terms
Detection of internal exon deletion with exon Del.
Guo Y, Zhao S, Lehmann BD, Sheng Q, Shaver TM, Stricker TP, Pietenpol JA, Shyr Y
(2014) BMC Bioinformatics 15: 332
MeSH Terms: DNA Copy Number Variations, Exome, Exons, Genome, Human, Genomics, Homozygote, Humans, Sequence Analysis, DNA, Sequence Deletion
Added January 20, 2015
1 Communities
3 Members
0 Resources
9 MeSH Terms
ANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 site.
Almodóvar-García K, Kwon M, Samaras SE, Davidson JM
(2014) Mol Cell Biol 34: 1500-11
MeSH Terms: Animals, Cell Line, Fibroblasts, Gene Expression, Matrix Metalloproteinase 13, Mice, Mice, Knockout, Muscle Proteins, Nuclear Proteins, Phosphoproteins, Promoter Regions, Genetic, RNA, Messenger, RNA-Binding Proteins, Repressor Proteins, Sequence Deletion, Transcription Factor AP-1
Added January 20, 2015
1 Communities
0 Members
0 Resources
16 MeSH Terms
SIN-dependent phosphoinhibition of formin multimerization controls fission yeast cytokinesis.
Bohnert KA, Grzegorzewska AP, Willet AH, Vander Kooi CW, Kovar DR, Gould KL
(2013) Genes Dev 27: 2164-77
MeSH Terms: Actin Cytoskeleton, Cytokinesis, Cytoskeletal Proteins, Phosphorylation, Protein Kinases, Protein Multimerization, Protein Structure, Tertiary, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Sequence Deletion
Added March 7, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Mitochondrial DNA rearrangements in health and disease--a comprehensive study.
Damas J, Samuels DC, Carneiro J, Amorim A, Pereira F
(2014) Hum Mutat 35: 1-14
MeSH Terms: Aging, DNA, Mitochondrial, Gene Rearrangement, Genome, Mitochondrial, Humans, Mitochondria, Mitochondrial Diseases, Neoplasms, Nucleic Acid Conformation, Regulatory Sequences, Nucleic Acid, Sequence Deletion
Added December 12, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ
(2013) J Clin Invest 123: 4390-404
MeSH Terms: Animals, Carcinogenesis, Carcinoma, Squamous Cell, Cell Dedifferentiation, Cell Proliferation, Epithelial-Mesenchymal Transition, Female, Gene Expression Regulation, Neoplastic, Humans, Mice, Mice, Nude, Mice, Transgenic, MicroRNAs, Mutation, Missense, Neoplasm Transplantation, Neoplastic Stem Cells, Proto-Oncogene Proteins, Proto-Oncogene Proteins p21(ras), RNA Interference, Sequence Deletion, Side-Population Cells, Skin Neoplasms, Smad4 Protein, Tumor Cells, Cultured, alpha Catenin, ras Proteins
Added September 27, 2013
1 Communities
0 Members
0 Resources
26 MeSH Terms