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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 28

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Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography.
Koran ME, Hohman TJ, Thornton-Wells TA
(2014) Hum Genet 133: 85-93
MeSH Terms: Aged, Aged, 80 and over, Alzheimer Disease, Amyloid beta-Peptides, Apolipoprotein E4, Brain, Calcium Channels, L-Type, Chromosome Mapping, Epistasis, Genetic, Female, Genotype, Homeostasis, Humans, Male, Polymorphism, Single Nucleotide, Positron-Emission Tomography, Reproducibility of Results, Ryanodine Receptor Calcium Release Channel
Added December 10, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.
Aistrup GL, Gupta DK, Kelly JE, O'Toole MJ, Nahhas A, Chirayil N, Misener S, Beussink L, Singh N, Ng J, Reddy M, Mongkolrattanothai T, El-Bizri N, Rajamani S, Shryock JC, Belardinelli L, Shah SJ, Wasserstrom JA
(2013) Am J Physiol Heart Circ Physiol 305: H1068-79
MeSH Terms: Acetanilides, Animals, Calcium Channels, L-Type, Calcium Signaling, Disease Models, Animal, Disease Progression, Dose-Response Relationship, Drug, Heart Failure, Hypertension, Hypertrophy, Left Ventricular, Male, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Piperazines, Ranolazine, Rats, Rats, Inbred SHR, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Sodium, Sodium Channel Blockers, Sodium Channels, Sodium-Calcium Exchanger, Time Factors, Ultrasonography
Added February 28, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Triadin regulates cardiac muscle couplon structure and microdomain Ca(2+) signalling: a path towards ventricular arrhythmias.
Chopra N, Knollmann BC
(2013) Cardiovasc Res 98: 187-91
MeSH Terms: Animals, Calcium Channels, L-Type, Calcium Signaling, Calsequestrin, Carrier Proteins, Excitation Contraction Coupling, Humans, Membrane Microdomains, Muscle Proteins, Myocytes, Cardiac, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Tachycardia, Ventricular
Added February 12, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR, Bers DM
(2010) Circ Res 106: 1743-52
MeSH Terms: Animals, Blotting, Western, Calcium Signaling, Cell Membrane Permeability, Circular Dichroism, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Fluorescence Recovery After Photobleaching, Heart Ventricles, Humans, Kinetics, Mice, Mice, Knockout, Microscopy, Confocal, Mutagenesis, Site-Directed, Mutation, Myocytes, Cardiac, Phosphorylation, Protein Binding, Rats, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sirolimus, Swine, Tacrolimus Binding Protein 1A, Tacrolimus Binding Proteins
Added May 27, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.
Hilliard FA, Steele DS, Laver D, Yang Z, Le Marchand SJ, Chopra N, Piston DW, Huke S, Knollmann BC
(2010) J Mol Cell Cardiol 48: 293-301
MeSH Terms: Animals, Arrhythmias, Cardiac, Calcium, Calcium Channel Blockers, Calcium Signaling, Calcium-Binding Proteins, Cell Membrane Permeability, Flecainide, Humans, Mice, Myocytes, Cardiac, Rats, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Tetracaine
Added December 6, 2012
0 Communities
2 Members
0 Resources
15 MeSH Terms
Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias.
Bush WS, Crawford DC, Alexander C, George AL, Roden DM, Ritchie MD
(2009) Pharmacogenomics 10: 1043-53
MeSH Terms: African Americans, Algorithms, Alleles, Ankyrins, Arrhythmias, Cardiac, Asian Continental Ancestry Group, Bayes Theorem, Cell Line, Cluster Analysis, DNA, ERG1 Potassium Channel, Ether-A-Go-Go Potassium Channels, European Continental Ancestry Group, Gene Frequency, Genetic Markers, Genetic Variation, Genetics, Population, Genome-Wide Association Study, Haplotypes, Humans, KCNQ1 Potassium Channel, Linkage Disequilibrium, Mexican Americans, Monte Carlo Method, Muscle Proteins, NAV1.5 Voltage-Gated Sodium Channel, Polymorphism, Single Nucleotide, Potassium Channels, Voltage-Gated, Ryanodine Receptor Calcium Release Channel, Sodium Channels, Software, United States
Added December 10, 2013
0 Communities
2 Members
0 Resources
32 MeSH Terms
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.
Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE, Duff HJ, Roden DM, Wilde AA, Knollmann BC
(2009) Nat Med 15: 380-3
MeSH Terms: Animals, Anti-Arrhythmia Agents, Arrhythmias, Cardiac, Calcium, Child, Flecainide, Heart Rate, Humans, Male, Mice, Polymorphism, Genetic, Ryanodine Receptor Calcium Release Channel, Syndrome, Tachycardia, Ventricular
Added June 1, 2013
1 Communities
2 Members
0 Resources
14 MeSH Terms
Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release.
Chopra N, Laver D, Davies SS, Knollmann BC
(2009) Mol Pharmacol 75: 183-95
MeSH Terms: Amitriptyline, Animals, Antidepressive Agents, Tricyclic, Calcium, Cells, Cultured, Dose-Response Relationship, Drug, Female, Fluorescent Dyes, Fura-2, Heart Ventricles, Male, Mice, Mice, Inbred C57BL, Myocytes, Cardiac, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Time Factors
Added June 1, 2013
1 Communities
1 Members
0 Resources
17 MeSH Terms
Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes.
Huke S, Bers DM
(2008) Biochem Biophys Res Commun 376: 80-5
MeSH Terms: Animals, Antibodies, Phospho-Specific, Base Sequence, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cells, Cultured, Cyclic AMP-Dependent Protein Kinases, Isoproterenol, Myocytes, Cardiac, Phosphoric Monoester Hydrolases, Phosphorylation, Phosphoserine, Rats, Ryanodine Receptor Calcium Release Channel, Serine
Added May 27, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Differential effects of phospholamban and Ca2+/calmodulin-dependent kinase II on [Ca2+]i transients in cardiac myocytes at physiological stimulation frequencies.
Werdich AA, Lima EA, Dzhura I, Singh MV, Li J, Anderson ME, Baudenbacher FJ
(2008) Am J Physiol Heart Circ Physiol 294: H2352-62
MeSH Terms: Adaptation, Physiological, Animals, Calcium Signaling, Calcium-Binding Proteins, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cardiac Pacing, Artificial, Cytosol, Mice, Mice, Knockout, Mice, Transgenic, Myocytes, Cardiac, Peptides, Recombinant Fusion Proteins, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Time Factors
Added August 13, 2010
1 Communities
0 Members
0 Resources
17 MeSH Terms