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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 58

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Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells.
Ueda Y, Neel NF, Schutyser E, Raman D, Richmond A
(2006) Cancer Res 66: 5665-75
MeSH Terms: Breast Neoplasms, Cell Communication, Cell Growth Processes, Cell Line, Tumor, Cell Movement, Down-Regulation, Enzyme Activation, Epithelial Cells, Genetic Vectors, Humans, Mesoderm, Mitogen-Activated Protein Kinase Kinases, Oligonucleotide Array Sequence Analysis, Protein Structure, Tertiary, Receptors, CXCR4, Retroviridae, Structure-Activity Relationship, Transduction, Genetic
Added May 30, 2013
2 Communities
2 Members
0 Resources
18 MeSH Terms
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.
Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H
(2006) J Biol Chem 281: 3198-203
MeSH Terms: Angiotensin-Converting Enzyme 2, Animals, Carboxypeptidases, Cathepsin L, Cathepsins, Cell Line, Chlorocebus aethiops, Coronavirus, Cysteine Endopeptidases, Endosomes, Green Fluorescent Proteins, Humans, Lysosomes, Membrane Glycoproteins, Peptidyl-Dipeptidase A, Retroviridae, SARS Virus, Species Specificity, Vero Cells, Viral Envelope Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.
Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK
(2005) Mol Cancer Res 3: 307-15
MeSH Terms: Animals, Binding Sites, Cell Line, Transformed, Cell Movement, Cells, Cultured, Collagen, Cytoskeletal Proteins, Drug Combinations, Enzyme Activation, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Genes, src, Injections, Subcutaneous, Laminin, Lung Neoplasms, Matrix Metalloproteinase 2, Mice, Mice, Nude, Neoplasm Invasiveness, Neoplasm Transplantation, Oncogene Protein v-crk, Paxillin, Phosphoproteins, Phosphorylation, Protein-Tyrosine Kinases, Proteoglycans, Retroviridae Proteins, Oncogenic, Tyrosine, src Homology Domains
Added February 24, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms
Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype.
Williams K, Fernandez S, Stien X, Ishii K, Love HD, Lau YF, Roberts RL, Hayward SW
(2005) Prostate 63: 369-84
MeSH Terms: Adenocarcinoma, Animals, Biomarkers, Tumor, Cells, Cultured, Disease Models, Animal, Epithelium, Gene Expression Regulation, Neoplastic, Gene Transfer Techniques, Green Fluorescent Proteins, Humans, Male, Mice, Mice, SCID, Oligonucleotide Array Sequence Analysis, Phenotype, Prostate, Prostatic Neoplasms, Proto-Oncogene Proteins c-myc, Retroviridae
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
Halder SK, Beauchamp RD, Datta PK
(2005) Exp Cell Res 307: 231-46
MeSH Terms: Animals, Apoptosis, Blotting, Western, COS Cells, Cell Line, Chlorocebus aethiops, DNA-Binding Proteins, Dose-Response Relationship, Drug, Gene Expression Regulation, Neoplastic, Growth Inhibitors, Humans, Mice, Mice, Nude, Neoplasm Transplantation, Neoplasms, Precipitin Tests, Retroviridae, Signal Transduction, Smad7 Protein, Trans-Activators, Transcription, Genetic, Transfection, Transforming Growth Factor beta, Transplantation, Heterologous
Added June 14, 2013
1 Communities
1 Members
0 Resources
24 MeSH Terms
Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes.
Hintermann E, Yang N, O'Sullivan D, Higgins JM, Quaranta V
(2005) J Biol Chem 280: 8004-15
MeSH Terms: Cadherins, Cell Adhesion, Cell Adhesion Molecules, Cell Communication, Cell Line, Cell Line, Tumor, Cell Movement, Dimerization, Extracellular Matrix, Genes, Dominant, Glutathione Transferase, Humans, Immunoprecipitation, Integrin alpha6beta4, Integrins, Keratinocytes, Ligands, Microscopy, Fluorescence, Neoplasms, Phosphatidylinositol 3-Kinases, Protein Binding, Receptor, ErbB-2, Retroviridae, Signal Transduction, Up-Regulation, Wound Healing, cdc42 GTP-Binding Protein
Added February 18, 2013
2 Communities
1 Members
0 Resources
27 MeSH Terms
Cloning and expression of canine O6-methylguanine-DNA methyltransferase in target cells, using gammaretroviral and lentiviral vectors.
Zaboikin M, Srinivasakumar N, Zaboikina T, Schuening F
(2004) Hum Gene Ther 15: 383-92
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Carmustine, Cell Division, Cells, Cultured, Cloning, Molecular, Dogs, Genetic Vectors, HIV-1, Humans, Kidney, Lentivirus, Molecular Sequence Data, Moloney murine leukemia virus, Mutation, O(6)-Methylguanine-DNA Methyltransferase, Retroviridae, Sequence Homology, Amino Acid
Added June 15, 2010
0 Communities
1 Members
0 Resources
19 MeSH Terms
Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility.
Ueda Y, Wang S, Dumont N, Yi JY, Koh Y, Arteaga CL
(2004) J Biol Chem 279: 24505-13
MeSH Terms: Actins, Activin Receptors, Type I, Adenoviridae, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Blotting, Northern, Breast Neoplasms, Bromodeoxyuridine, Butadienes, Cell Cycle, Cell Division, Cell Line, Cell Line, Tumor, Cell Movement, Chromones, DNA, Complementary, Disease Progression, Enzyme Inhibitors, Epithelial Cells, Gene Expression Regulation, Genes, Reporter, Green Fluorescent Proteins, Humans, Imidazoles, Immunoblotting, Integrin beta1, Ligands, Luminescent Proteins, Microscopy, Fluorescence, Models, Genetic, Morpholines, Nitriles, Phosphoinositide-3 Kinase Inhibitors, Precipitin Tests, Protein Serine-Threonine Kinases, Pseudopodia, Pyridines, Receptor, ErbB-2, Receptor, Transforming Growth Factor-beta Type I, Receptors, Transforming Growth Factor beta, Retroviridae, Signal Transduction, Transcription, Genetic, Transforming Growth Factor beta, Trastuzumab, Wound Healing, rac1 GTP-Binding Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
47 MeSH Terms
EGFR signaling to p120-catenin through phosphorylation at Y228.
Mariner DJ, Davis MA, Reynolds AB
(2004) J Cell Sci 117: 1339-50
MeSH Terms: 3T3 Cells, Adherens Junctions, Animals, Antibodies, Monoclonal, COS Cells, Cadherins, Catenins, Cell Adhesion Molecules, Cell Line, Tumor, Chlorocebus aethiops, Enzyme Activation, ErbB Receptors, Humans, Mice, Mutation, NIH 3T3 Cells, Phosphoproteins, Phosphorylation, Pseudopodia, RNA, Small Interfering, Retroviridae, Tyrosine, src-Family Kinases
Added March 5, 2014
1 Communities
1 Members
0 Resources
23 MeSH Terms
Gene therapy insertional mutagenesis insights.
Davé UP, Jenkins NA, Copeland NG
(2004) Science 303: 333
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, DNA-Binding Proteins, Gene Expression, Genetic Therapy, Genetic Vectors, Humans, LIM Domain Proteins, Leukemia, T-Cell, Metalloproteins, Mice, Mutagenesis, Insertional, Proto-Oncogene Proteins, Receptors, Interleukin-2, Retroviridae, Severe Combined Immunodeficiency, Virus Integration
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms