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Results: 11 to 20 of 38

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Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding.
Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV
(2013) Cell Signal 25: 2155-62
MeSH Terms: Animals, Arrestin, Cattle, Cholesterol, HDL, G-Protein-Coupled Receptor Kinase 1, Gene Expression Regulation, Isoenzymes, Mutation, Night Blindness, Opsins, Phosphoproteins, Phosphorylation, Protein Binding, Protein Isoforms, Protein Multimerization, Retinal Rod Photoreceptor Cells, Rhodopsin, Signal Transduction
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Identification of key factors that reduce the variability of the single photon response.
Caruso G, Bisegna P, Andreucci D, Lenoci L, Gurevich VV, Hamm HE, DiBenedetto E
(2011) Proc Natl Acad Sci U S A 108: 7804-7
MeSH Terms: Animals, Calcium, Cyclic GMP, Light, Light Signal Transduction, Mice, Models, Biological, Photons, Retinal Rod Photoreceptor Cells, Rhodopsin, Rod Cell Outer Segment, Second Messenger Systems, Stochastic Processes
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Robust self-association is a common feature of mammalian visual arrestin-1.
Kim M, Hanson SM, Vishnivetskiy SA, Song X, Cleghorn WM, Hubbell WL, Gurevich VV
(2011) Biochemistry 50: 2235-42
MeSH Terms: Animals, Arrestins, Cattle, Humans, Mice, Models, Molecular, Point Mutation, Protein Multimerization, Protein Structure, Quaternary, Rabbits, Retinal Rod Photoreceptor Cells
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Kinetics of rhodopsin deactivation and its role in regulating recovery and reproducibility of rod photoresponse.
Caruso G, Bisegna P, Lenoci L, Andreucci D, Gurevich VV, Hamm HE, DiBenedetto E
(2010) PLoS Comput Biol 6: e1001031
MeSH Terms: Animals, Arrestin, Computational Biology, G-Protein-Coupled Receptor Kinase 1, Kinetics, Markov Chains, Mice, Mice, Transgenic, Models, Neurological, Phosphorylation, Photons, Reproducibility of Results, Retinal Rod Photoreceptor Cells, Rhodopsin
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health.
Song X, Vishnivetskiy SA, Seo J, Chen J, Gurevich EV, Gurevich VV
(2011) Neuroscience 174: 37-49
MeSH Terms: Animals, Arrestins, Darkness, Electroretinography, Mice, Mice, Transgenic, Photoreceptor Cells, Vertebrate, Retinal Rod Photoreceptor Cells, Rod Cell Outer Segment
Added December 10, 2013
0 Communities
1 Members
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9 MeSH Terms
Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation.
Song X, Vishnivetskiy SA, Gross OP, Emelianoff K, Mendez A, Chen J, Gurevich EV, Burns ME, Gurevich VV
(2009) Curr Biol 19: 700-5
MeSH Terms: Animals, Arrestin, Electroretinography, G-Protein-Coupled Receptor Kinase 1, Mice, Mice, Knockout, Mutation, Phosphorylation, Retinal Rod Photoreceptor Cells, Rhodopsin
Added December 10, 2013
0 Communities
1 Members
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10 MeSH Terms
Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors.
Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL
(2009) Biophys J 96: 939-50
MeSH Terms: Absorption, Animals, Cattle, Cell Membrane, Fatty Acids, Gene Expression, Light, Mice, Mice, Transgenic, Retinal Rod Photoreceptor Cells, Rhodopsin, Rod Opsins
Added December 10, 2013
0 Communities
1 Members
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12 MeSH Terms
Expression of genes encoding glutamate receptors and transporters in rod and cone bipolar cells of the primate retina determined by single-cell polymerase chain reaction.
Hanna MC, Calkins DJ
(2007) Mol Vis 13: 2194-208
MeSH Terms: Animals, Cell Separation, Female, Gene Expression Regulation, Gene Library, Male, Membrane Transport Proteins, Polymerase Chain Reaction, Primates, Protein Subunits, Receptors, Glutamate, Retinal Bipolar Cells, Retinal Cone Photoreceptor Cells, Retinal Rod Photoreceptor Cells
Added February 12, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Functional comparisons of visual arrestins in rod photoreceptors of transgenic mice.
Chan S, Rubin WW, Mendez A, Liu X, Song X, Hanson SM, Craft CM, Gurevich VV, Burns ME, Chen J
(2007) Invest Ophthalmol Vis Sci 48: 1968-75
MeSH Terms: Animals, Arrestins, Blotting, Western, Electrophoresis, Polyacrylamide Gel, Electrophysiology, Fluorescent Antibody Technique, Indirect, Gene Expression, Light, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Phosphorylation, Photic Stimulation, Retinal Cone Photoreceptor Cells, Retinal Rod Photoreceptor Cells, Reverse Transcriptase Polymerase Chain Reaction, Rhodopsin, Vision, Ocular, beta-Arrestin 1, beta-Arrestins
Added December 10, 2013
0 Communities
1 Members
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21 MeSH Terms
Each rhodopsin molecule binds its own arrestin.
Hanson SM, Gurevich EV, Vishnivetskiy SA, Ahmed MR, Song X, Gurevich VV
(2007) Proc Natl Acad Sci U S A 104: 3125-8
MeSH Terms: Animals, Arrestin, Dimerization, Immunohistochemistry, Mice, Mice, Knockout, Models, Molecular, Protein Binding, Protein Transport, Retinal Rod Photoreceptor Cells, Rhodopsin
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms