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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 148

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Deleting the TGF-β receptor in proximal tubules impairs HGF signaling.
Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L
(2016) Am J Physiol Renal Physiol 310: F499-510
MeSH Terms: Amyloid Precursor Protein Secretases, Animals, Cells, Cultured, Hepatocyte Growth Factor, Kidney Tubules, Proximal, Mice, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-met, Receptor, Transforming Growth Factor-beta Type II, Receptors, Notch, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta
Added January 29, 2016
1 Communities
3 Members
0 Resources
13 MeSH Terms
Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB
(2015) Gastroenterology 149: 1932-1943.e9
MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Pancreatic Ductal, Cell Line, Tumor, Collagen, Deoxycytidine, Drug Resistance, Neoplasm, Gene Knockdown Techniques, Humans, Mice, Inbred C57BL, Mice, Nude, Mice, Transgenic, Molecular Targeted Therapy, Neoplasm Staging, Osteonectin, Pancreatic Neoplasms, Phosphorylation, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins p21(ras), Pyrazoles, Pyrimidines, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, STAT3 Transcription Factor, Signal Transduction, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Stromal Cells, Time Factors, Transcription Factors, Transfection, Tumor Burden, Tumor Microenvironment, Xenograft Model Antitumor Assays
Added October 15, 2015
2 Communities
3 Members
0 Resources
33 MeSH Terms
Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II.
Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier S, Basu S, Guelcher SA, Sterling JA
(2015) Biomaterials 64: 33-44
MeSH Terms: Adenocarcinoma, Animals, Bone Neoplasms, Breast Neoplasms, Carcinoma, Squamous Cell, Cell Line, Tumor, Elastic Modulus, Extracellular Matrix, Female, Gene Expression Regulation, Neoplastic, Humans, Integrin beta3, Kruppel-Like Transcription Factors, Lung Neoplasms, Mice, Mice, Nude, Neoplasm Proteins, Nuclear Proteins, Osteolysis, Pliability, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Transfection, Transforming Growth Factor beta, Tumor Microenvironment, Xenograft Model Antitumor Assays, Zinc Finger Protein Gli2
Added February 23, 2016
1 Communities
2 Members
0 Resources
28 MeSH Terms
Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells.
Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L
(2015) Kidney Int 88: 503-14
MeSH Terms: Actins, Animals, Aristolochic Acids, Cells, Cultured, Collagen Type I, Disease Models, Animal, Extracellular Matrix, Fibrosis, Kidney, Kidney Diseases, Mice, Inbred C57BL, Mice, Knockout, Protein-Serine-Threonine Kinases, Receptor, Platelet-Derived Growth Factor beta, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Time Factors, Transforming Growth Factor beta, Ureteral Obstruction
Added August 3, 2015
1 Communities
3 Members
0 Resources
20 MeSH Terms
TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions.
Shaw AK, Pickup MW, Chytil A, Aakre M, Owens P, Moses HL, Novitskiy SV
(2015) PLoS One 10: e0117908
MeSH Terms: Animals, Cell Line, Tumor, Cell Movement, Female, Fibroblasts, Mammary Neoplasms, Experimental, Mice, Myeloid Cells, Neoplasm Invasiveness, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta
Added February 12, 2015
1 Communities
2 Members
0 Resources
14 MeSH Terms
Increased pSmad2 expression and cytoplasmic predominant presence of TGF-βRII in breast cancer tissue are associated with poor prognosis: results from the Shanghai Breast Cancer Study.
Qiu Q, Su Y, Zheng Y, Cai H, Wu S, Lu W, Zheng W, Shu XO, Cai Q
(2015) Breast Cancer Res Treat 149: 467-77
MeSH Terms: Adult, Aged, Breast Neoplasms, China, Cytoplasm, Female, Gene Expression, Humans, Immunohistochemistry, Middle Aged, Neoplasm Grading, Neoplasm Staging, Prognosis, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Risk Factors, Smad2 Protein, Tumor Burden
Added January 20, 2015
0 Communities
2 Members
0 Resources
19 MeSH Terms
Type III TGFβ receptor and Src direct hyaluronan-mediated invasive cell motility.
Allison P, Espiritu D, Barnett JV, Camenisch TD
(2015) Cell Signal 27: 453-9
MeSH Terms: Actin Cytoskeleton, Amino Acid Substitution, Animals, Arrestin, Cell Movement, Cells, Cultured, Epithelial-Mesenchymal Transition, Hyaluronic Acid, Mice, Neuropeptides, Pericardium, Protein Binding, Proteoglycans, RNA Interference, RNA, Small Interfering, Receptors, Transforming Growth Factor beta, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, rho GTP-Binding Proteins, rhoA GTP-Binding Protein, src-Family Kinases
Added February 21, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis.
Hill CR, Jacobs BH, Brown CB, Barnett JV, Goudy SL
(2015) Dev Dyn 244: 122-33
MeSH Terms: Animals, Antigens, Differentiation, Calcification, Physiologic, Gene Expression Regulation, Developmental, Mesoderm, Mice, Mice, Knockout, Neovascularization, Physiologic, Organogenesis, Osteoblasts, Palate, Hard, Proteoglycans, Receptors, Transforming Growth Factor beta
Added February 19, 2015
0 Communities
2 Members
0 Resources
13 MeSH Terms
Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma.
Andl T, Le Bras GF, Richards NF, Allison GL, Loomans HA, Washington MK, Revetta F, Lee RK, Taylor C, Moses HL, Andl CD
(2014) Carcinogenesis 35: 2602-10
MeSH Terms: Animals, Antigens, CD, Cadherins, Carcinogenesis, Carcinoma, Squamous Cell, Cell Proliferation, Cyclin D1, Epithelial Cells, Homeostasis, Humans, Mice, Mouth Neoplasms, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Tamoxifen
Added December 3, 2014
2 Communities
3 Members
0 Resources
17 MeSH Terms
Role of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumors.
Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV
(2014) J Immunol 193: 3155-64
MeSH Terms: 5'-Nucleotidase, Animals, Antigens, CD, Apyrase, Bone Marrow Cells, Carcinoma, Lewis Lung, Cell Differentiation, Cell Line, Tumor, Cell Movement, Female, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Cells, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, T-Lymphocytes, Transforming Growth Factor beta, Tumor Microenvironment, Vascular Endothelial Growth Factor A
Added December 3, 2014
2 Communities
2 Members
0 Resources
24 MeSH Terms