Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling.
Kovanen PE, Rosenwald A, Fu J, Hurt EM, Lam LT, Giltnane JM, Wright G, Staudt LM, Leonard WJ
(2003) J Biol Chem 278
: 5205-13MeSH Terms: Cells, Cultured, Dual-Specificity Phosphatases, Gene Expression Regulation, Humans, Interleukin-2, MAP Kinase Signaling System, Protein Tyrosine Phosphatases, Receptors, Cytokine, Signal Transduction, T-LymphocytesAdded March 5, 2014
10 MeSH Terms
Interferon-gamma production is suppressed in thermally injured mice: decreased production of regulatory cytokines and corresponding receptors.
Toliver-Kinsky TE, Varma TK, Lin CY, Herndon DN, Sherwood ER
(2002) Shock 18
: 322-30MeSH Terms: Animals, Burns, Cells, Cultured, Coculture Techniques, Cytokines, Female, Interferon-gamma, Interleukin-10, Interleukin-12, Killer Cells, Natural, Lymphocytes, Macrophages, Mice, Mice, Inbred BALB C, Pseudomonas aeruginosa, Receptors, Cytokine, SpleenAdded October 18, 2015
17 MeSH Terms
Redirection of T cell effector function in vivo and enhanced collagen-induced arthritis mediated by an IL-2R beta/IL-4R alpha chimeric cytokine receptor transgene.
Chen Y, Rosloniec E, Goral MI, Boothby M, Chen J
(2001) J Immunol 166
: 4163-9MeSH Terms: Amino Acid Sequence, Animals, Arthritis, Experimental, Autoantibodies, Cattle, Cell Movement, Collagen, Cytokines, Eosinophils, Epitopes, T-Lymphocyte, Hindlimb, Immunoglobulin G, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, Transgenic, Molecular Sequence Data, Receptors, Cytokine, Receptors, Interleukin-2, Receptors, Interleukin-4, Recombinant Fusion Proteins, Th2 Cells, Transgenes, Up-RegulationAdded December 10, 2013
25 MeSH Terms
Chemokine and chemokine receptor expression in keloid and normal fibroblasts.
Nirodi CS, Devalaraja R, Nanney LB, Arrindell S, Russell S, Trupin J, Richmond A
(2000) Wound Repair Regen 8
: 371-82MeSH Terms: Blotting, Northern, Case-Control Studies, Cells, Cultured, Chemokine CXCL1, Chemokines, Chemokines, CXC, Chemotactic Factors, Cicatrix, Fibroblasts, Gene Expression, Genetic Predisposition to Disease, Growth Substances, Humans, Immunohistochemistry, Intercellular Signaling Peptides and Proteins, Interleukin-1, Keloid, Receptors, Cytokine, Receptors, Interleukin-8B, Wound HealingAdded May 30, 2013
20 MeSH Terms
MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression.
Wang D, Yang W, Du J, Devalaraja MN, Liang P, Matsumoto K, Tsubakimoto K, Endo T, Richmond A
(2000) Oncogene 19
: 4647-59MeSH Terms: Animals, Autocrine Communication, Cell Line, Transformed, Cell Transformation, Neoplastic, Chemokine CXCL1, Chemokines, CXC, Chemotactic Factors, Clone Cells, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genes, Reporter, Genes, ras, Growth Substances, Humans, Intercellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Melanocytes, Melanoma, Mice, Monomeric GTP-Binding Proteins, Neoplasm Proteins, Protein Isoforms, RNA, Messenger, RNA, Neoplasm, Receptors, Cytokine, Recombinant Fusion Proteins, Signal Transduction, Subtraction Technique, Transcription Factor AP-1, Transfection, ras ProteinsAdded May 30, 2013
31 MeSH Terms
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R
(2000) Nature 405
: 966-70MeSH Terms: Alleles, Animals, Cloning, Molecular, Embryo, Mammalian, Embryonic and Fetal Development, Fetal Death, Gene Targeting, Germ-Line Mutation, Homozygote, Immunoglobulins, In Situ Hybridization, Ligands, Membrane Proteins, Mice, Mice, Inbred C57BL, Phenotype, Point Mutation, Protein Processing, Post-Translational, Receptor, Notch1, Receptors, Cell Surface, Receptors, Cytokine, Transcription FactorsAdded January 11, 2011
22 MeSH Terms
Cytokines revisited at Hilton head.
Richmond A, Kaempfer R
(2000) Cytokine Growth Factor Rev 11
: 255-66MeSH Terms: Animals, Apoptosis, Autoimmune Diseases, Cardiovascular Diseases, Cell Differentiation, Chemokines, Cytokines, Disease Models, Animal, Gene Expression Regulation, Humans, Inflammation, Receptors, Cytokine, Signal TransductionAdded May 30, 2013
13 MeSH Terms
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion.
Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, Littman DR
(2000) Mol Cell Biol 20
: 4106-14MeSH Terms: Animals, CX3C Chemokine Receptor 1, Gene Expression, Gene Targeting, Genes, Reporter, Green Fluorescent Proteins, Luminescent Proteins, Mice, Mice, Mutant Strains, Mutagenesis, Insertional, Phenotype, Receptors, Cytokine, Receptors, HIVAdded August 11, 2015
13 MeSH Terms
Distinct roles for signals relayed through the common cytokine receptor gamma chain and interleukin 7 receptor alpha chain in natural T cell development.
Boesteanu A, Silva AD, Nakajima H, Leonard WJ, Peschon JJ, Joyce S
(1997) J Exp Med 186
: 331-6MeSH Terms: Animals, Antigens, CD, Interleukin-2, Interleukin-4, Mice, Receptors, Cytokine, Receptors, Interleukin, Receptors, Interleukin-2, Receptors, Interleukin-7, Signal Transduction, T-LymphocytesAdded October 2, 2015
11 MeSH Terms
Sepsis and cytokines: current status.
Blackwell TS, Christman JW
(1996) Br J Anaesth 77
: 110-7MeSH Terms: Cytokines, Humans, Interleukin-1, Interleukin-10, Interleukin-6, Interleukin-8, Receptors, Cytokine, Receptors, Interleukin-1, Systemic Inflammatory Response Syndrome, Tumor Necrosis Factor-alphaAdded March 5, 2014
10 MeSH Terms