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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 102

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Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.
Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE
(2017) Mol Oncol 11: 405-421
MeSH Terms: Animals, Base Sequence, Cell Movement, Cell Proliferation, Cell Transformation, Neoplastic, Disease Progression, Enzyme Activation, Humans, Immunohistochemistry, Kidney Neoplasms, Mice, Inbred C57BL, Mutation, Neoplasm Metastasis, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins p21(ras), Wilms Tumor, beta Catenin
Added May 5, 2017
1 Communities
2 Members
0 Resources
18 MeSH Terms
Integrated genomic and molecular characterization of cervical cancer.
Cancer Genome Atlas Research Network, Albert Einstein College of Medicine, Analytical Biological Services, Barretos Cancer Hospital, Baylor College of Medicine, Beckman Research Institute of City of Hope, Buck Institute for Research on Aging, Canada's Michael Smith Genome Sciences Centre, Harvard Medical School, Helen F. Graham Cancer Center &Research Institute at Christiana Care Health Services, HudsonAlpha Institute for Biotechnology, ILSbio, LLC, Indiana University School of Medicine, Institute of Human Virology, Institute for Systems Biology, International Genomics Consortium, Leidos Biomedical, Massachusetts General Hospital, McDonnell Genome Institute at Washington University, Medical College of Wisconsin, Medical University of South Carolina, Memorial Sloan Kettering Cancer Center, Montefiore Medical Center, NantOmics, National Cancer Institute, National Hospital, Abuja, Nigeria, National Human Genome Research Institute, National Institute of Environmental Health Sciences, National Institute on Deafness &Other Communication Disorders, Ontario Tumour Bank, London Health Sciences Centre, Ontario Tumour Bank, Ontario Institute for Cancer Research, Ontario Tumour Bank, The Ottawa Hospital, Oregon Health &Science University, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, SRA International, St Joseph's Candler Health System, Eli &Edythe L. Broad Institute of Massachusetts Institute of Technology &Harvard University, Research Institute at Nationwide Children's Hospital, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, University of Bergen, University of Texas MD Anderson Cancer Center, University of Abuja Teaching Hospital, University of Alabama at Birmingham, University of California, Irvine, University of California Santa Cruz, University of Kansas Medical Center, University of Lausanne, University of New Mexico Health Sciences Center, University of North Carolina at Chapel Hill, University of Oklahoma Health Sciences Center, University of Pittsburgh, University of São Paulo, Ribeir ão Preto Medical School, University of Southern California, University of Washington, University of Wisconsin School of Medicine &Public Health, Van Andel Research Institute, Washington University in St Louis
(2017) Nature 543: 378-384
MeSH Terms: APOBEC-1 Deaminase, Adenocarcinoma, B7-H1 Antigen, Carcinoma, Squamous Cell, Caspase 8, DNA-Binding Proteins, Female, Genomics, HLA-A Antigens, Human papillomavirus 16, Humans, Keratins, Mitogen-Activated Protein Kinase Kinases, Molecular Targeted Therapy, Mutation, Nuclear Proteins, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Programmed Cell Death 1 Ligand 2 Protein, Protein-Serine-Threonine Kinases, Proteomics, Proto-Oncogene Proteins p21(ras), RNA, Long Noncoding, Receptor, ErbB-3, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transcription Factors, Uterine Cervical Neoplasms, Virus Integration
Added October 30, 2019
0 Communities
1 Members
0 Resources
30 MeSH Terms
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes.
Dou Y, Cha DJ, Franklin JL, Higginbotham JN, Jeppesen DK, Weaver AM, Prasad N, Levy S, Coffey RJ, Patton JG, Zhang B
(2016) Sci Rep 6: 37982
MeSH Terms: Cell Line, Tumor, Colonic Neoplasms, Down-Regulation, Exosomes, Gene Expression Regulation, Neoplastic, High-Throughput Nucleotide Sequencing, Humans, Proto-Oncogene Proteins p21(ras), RNA, RNA, Circular
Added April 26, 2017
0 Communities
3 Members
0 Resources
10 MeSH Terms
KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes.
McKenzie AJ, Hoshino D, Hong NH, Cha DJ, Franklin JL, Coffey RJ, Patton JG, Weaver AM
(2016) Cell Rep 15: 978-987
MeSH Terms: Argonaute Proteins, Cell Line, Tumor, Exosomes, Humans, MicroRNAs, Mitogen-Activated Protein Kinase Kinases, Multivesicular Bodies, Mutant Proteins, Phosphorylation, Phosphoserine, Protein Transport, Proto-Oncogene Proteins p21(ras), Signal Transduction, Subcellular Fractions
Added April 29, 2016
1 Communities
3 Members
0 Resources
14 MeSH Terms
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM
(2016) Nat Med 22: 497-505
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Chromatography, Liquid, Collagen, Disease Models, Animal, Disease Progression, Extracellular Matrix, Fibrosis, Genotype, Humans, Integrin beta Chains, Mice, Microscopy, Atomic Force, Mutation, Pancreatic Neoplasms, Prognosis, Proteomics, Proto-Oncogene Proteins p21(ras), Real-Time Polymerase Chain Reaction, STAT3 Transcription Factor, Signal Transduction, Smad4 Protein, Survival Rate, Tandem Mass Spectrometry, Transforming Growth Factor beta, Tumor Microenvironment
Added May 5, 2017
1 Communities
1 Members
0 Resources
26 MeSH Terms
Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation.
Drosos Y, Neale G, Ye J, Paul L, Kuliyev E, Maitra A, Means AL, Washington MK, Rehg J, Finkelstein DB, Sosa-Pineda B
(2016) Neoplasia 18: 172-84
MeSH Terms: Acinar Cells, Animals, Cell Transformation, Neoplastic, Ceruletide, Heterozygote, Homeodomain Proteins, Humans, Inflammation, Metaplasia, Mice, Pancreas, Pancreatic Neoplasms, Proto-Oncogene Proteins p21(ras), Tumor Suppressor Proteins
Added April 11, 2016
0 Communities
2 Members
0 Resources
14 MeSH Terms
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.
Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P
(2016) Cell Rep 14: 2325-36
MeSH Terms: ADAM17 Protein, Acinar Cells, Animals, Cells, Cultured, Epidermal Growth Factor, ErbB Receptors, Humans, Ligands, Mice, Mitochondria, Mutagenesis, Site-Directed, NF-kappa B p52 Subunit, Oxidative Stress, Pancreatic Neoplasms, Precancerous Conditions, Protein Kinase C, Proto-Oncogene Proteins p21(ras), RNA Interference, Reactive Oxygen Species, Signal Transduction, Up-Regulation
Added March 13, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Correlation between KRAS mutation status and response to chemotherapy in patients with advanced non-small cell lung cancer☆.
Hames ML, Chen H, Iams W, Aston J, Lovly CM, Horn L
(2016) Lung Cancer 92: 29-34
MeSH Terms: Aged, Carcinoma, Non-Small-Cell Lung, Female, Humans, Lung Neoplasms, Male, Middle Aged, Mutation, Neoplasm Metastasis, Neoplasm Recurrence, Local, Prognosis, Proto-Oncogene Proteins p21(ras), Retrospective Studies, Survival Analysis, Treatment Outcome
Added January 26, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Edmonds MD, Boyd KL, Moyo T, Mitra R, Duszynski R, Arrate MP, Chen X, Zhao Z, Blackwell TS, Andl T, Eischen CM
(2016) J Clin Invest 126: 349-64
MeSH Terms: Adenocarcinoma, Adenocarcinoma of Lung, Animals, Cell Line, Tumor, Female, Humans, Lung Neoplasms, MAP Kinase Signaling System, Male, Mice, MicroRNAs, Mutation, NIH 3T3 Cells, Proto-Oncogene Proteins p21(ras), ras Proteins
Added February 22, 2016
1 Communities
1 Members
0 Resources
15 MeSH Terms
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
Hrustanovic G, Olivas V, Pazarentzos E, Tulpule A, Asthana S, Blakely CM, Okimoto RA, Lin L, Neel DS, Sabnis A, Flanagan J, Chan E, Varella-Garcia M, Aisner DL, Vaishnavi A, Ou SH, Collisson EA, Ichihara E, Mack PC, Lovly CM, Karachaliou N, Rosell R, Riess JW, Doebele RC, Bivona TG
(2015) Nat Med 21: 1038-47
MeSH Terms: Anaplastic Lymphoma Kinase, Cell Line, Tumor, Drug Resistance, Neoplasm, Dual Specificity Phosphatase 6, Humans, Lung Neoplasms, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Oncogene Proteins, Fusion, Proto-Oncogene Proteins, Proto-Oncogene Proteins p21(ras), Receptor Protein-Tyrosine Kinases, ras Proteins
Added January 26, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms