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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 79

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Using avatars to win the fight over BRAF inhibitor resistance.
Vilgelm AE, Richmond A
(2016) Pigment Cell Melanoma Res 29: 398-9
MeSH Terms: Cell Line, Tumor, Drug Resistance, Neoplasm, Humans, Indoles, Melanoma, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf, Sulfonamides
Added April 18, 2017
1 Communities
2 Members
0 Resources
8 MeSH Terms
Guiding Oncology Patients Through the Maze of Precision Medicine.
Giuse NB, Kusnoor SV, Koonce TY, Naylor HM, Chen SC, Blasingame MN, Anderson IA, Micheel CM, Levy MA, Ye F, Lovly CM
(2016) J Health Commun 21 Suppl 1: 5-17
MeSH Terms: Adult, Aged, Caregivers, Decision Support Systems, Clinical, Female, Follow-Up Studies, Health Knowledge, Attitudes, Practice, Health Literacy, Humans, Male, Melanoma, Middle Aged, Mutation, Patient Education as Topic, Precision Medicine, Proto-Oncogene Proteins B-raf
Added April 17, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss.
Jolly LA, Novitskiy S, Owens P, Massoll N, Cheng N, Fang W, Moses HL, Franco AT
(2016) Cancer Res 76: 1804-13
MeSH Terms: Cell Proliferation, Collagen, Fibroblasts, Humans, PTEN Phosphohydrolase, Proto-Oncogene Proteins B-raf, Thyroid Neoplasms, Tumor Microenvironment
Added February 5, 2016
1 Communities
2 Members
0 Resources
8 MeSH Terms
In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAFV600E in melanoma.
Guo X, Xu Y, Zhao Z
(2015) Mol Cancer 14: 60
MeSH Terms: Cell Transformation, Neoplastic, DNA Methylation, Down-Regulation, Epigenesis, Genetic, Epigenomics, Gene Expression Regulation, Neoplastic, Genomics, Humans, Melanoma, Microphthalmia-Associated Transcription Factor, Proto-Oncogene Proteins B-raf, Skin Neoplasms, Transcription, Genetic, Transcriptome, Transforming Growth Factor beta1, Up-Regulation
Added April 6, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Preliminary results from a prospective trial of preoperative combined BRAF and MEK-targeted therapy in advanced BRAF mutation-positive melanoma.
Johnson AS, Crandall H, Dahlman K, Kelley MC
(2015) J Am Coll Surg 220: 581-93.e1
MeSH Terms: Administration, Oral, Adult, Aged, Biomarkers, Tumor, Biopsy, DNA Mutational Analysis, DNA, Neoplasm, Dose-Response Relationship, Drug, Drug Therapy, Combination, Feasibility Studies, Female, Follow-Up Studies, Humans, Imidazoles, MAP Kinase Kinase 1, Male, Melanoma, Middle Aged, Mitogen-Activated Protein Kinases, Mutation, Oximes, Preoperative Care, Prospective Studies, Proto-Oncogene Proteins B-raf, Pyridones, Pyrimidinones, Skin Neoplasms, Young Adult
Added February 16, 2016
0 Communities
1 Members
0 Resources
28 MeSH Terms
Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
Moriceau G, Hugo W, Hong A, Shi H, Kong X, Yu CC, Koya RC, Samatar AA, Khanlou N, Braun J, Ruchalski K, Seifert H, Larkin J, Dahlman KB, Johnson DB, Algazi A, Sosman JA, Ribas A, Lo RS
(2015) Cancer Cell 27: 240-56
MeSH Terms: Cell Line, Tumor, Drug Resistance, Neoplasm, Humans, MAP Kinase Signaling System, Melanoma, Molecular Targeted Therapy, Mutation, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf
Added February 13, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Ovarian mucinous tumor with malignant mural nodules: dedifferentiation or collision?
Desouki MM, Khabele D, Crispens MA, Fadare O
(2015) Int J Gynecol Pathol 34: 19-24
MeSH Terms: Carcinoma, Cell Movement, Cell Transformation, Neoplastic, Combined Modality Therapy, Drug Therapy, Female, Genes, ras, Humans, Mutation, Neoplasms, Cystic, Mucinous, and Serous, Ovarian Neoplasms, Ovariectomy, Proto-Oncogene Proteins B-raf, Treatment Outcome, Young Adult
Added February 19, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Myeloid IKK╬▓ promotes antitumor immunity by modulating CCL11 and the innate immune response.
Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A
(2014) Cancer Res 74: 7274-84
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Dendritic Cells, Humans, I-kappa B Kinase, Immunity, Innate, Macrophages, Melanoma, Experimental, Mice, Mice, Knockout, Myeloid Cells, NF-kappa B, Proto-Oncogene Proteins B-raf, Signal Transduction, Tumor Microenvironment
Added December 17, 2014
2 Communities
5 Members
0 Resources
15 MeSH Terms
Snowball: resampling combined with distance-based regression to discover transcriptional consequences of a driver mutation.
Xu Y, Guo X, Sun J, Zhao Z
(2015) Bioinformatics 31: 84-93
MeSH Terms: Algorithms, Computer Simulation, DNA Mutational Analysis, Gene Expression Profiling, Genomics, Humans, Melanoma, Models, Genetic, Mutation, Neoplasms, Proto-Oncogene Proteins B-raf, Regression Analysis
Added February 13, 2015
0 Communities
3 Members
0 Resources
12 MeSH Terms
BRAFV600E-mutant melanoma presenting with cardiac involvement.
Johnson DB, Sosman JA
(2014) J Natl Compr Canc Netw 12: 611-5
MeSH Terms: Adult, Heart Neoplasms, Humans, Male, Melanoma, Mutation, Proto-Oncogene Proteins B-raf, Skin Neoplasms
Added June 27, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms