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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 48

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Therapeutic potential of small molecules and engineered proteins.
Gurevich EV, Gurevich VV
(2014) Handb Exp Pharmacol 219: 1-12
MeSH Terms: Allosteric Regulation, Animals, Arrestins, Drug Delivery Systems, Drug Design, Humans, Ligands, Protein Binding, Protein Engineering
Added February 12, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Engineered protease-resistant antibodies with selectable cell-killing functions.
Kinder M, Greenplate AR, Grugan KD, Soring KL, Heeringa KA, McCarthy SG, Bannish G, Perpetua M, Lynch F, Jordan RE, Strohl WR, Brezski RJ
(2013) J Biol Chem 288: 30843-54
MeSH Terms: Antibodies, Monoclonal, Antibody-Dependent Cell Cytotoxicity, Binding Sites, Antibody, Cell Line, Humans, Immunoglobulin G, Protein Engineering, Proteolysis, Receptors, IgG
Added March 27, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Octarellin VI: using rosetta to design a putative artificial (β/α)8 protein.
Figueroa M, Oliveira N, Lejeune A, Kaufmann KW, Dorr BM, Matagne A, Martial JA, Meiler J, Van de Weerdt C
(2013) PLoS One 8: e71858
MeSH Terms: Amino Acid Sequence, Circular Dichroism, Escherichia coli, Molecular Dynamics Simulation, Molecular Sequence Data, Particle Size, Protein Denaturation, Protein Engineering, Protein Refolding, Protein Stability, Protein Structure, Secondary, Protein Structure, Tertiary, Recombinant Proteins, Software, Solubility, Thermodynamics
Added January 24, 2015
1 Communities
1 Members
0 Resources
16 MeSH Terms
Computational design of protein-small molecule interfaces.
Allison B, Combs S, DeLuca S, Lemmon G, Mizoue L, Meiler J
(2014) J Struct Biol 185: 193-202
MeSH Terms: Algorithms, Amino Acid Sequence, Binding Sites, Ligands, Molecular Docking Simulation, Protein Binding, Protein Engineering, Proteins, Software
Added January 24, 2015
1 Communities
1 Members
0 Resources
9 MeSH Terms
A novel experimental strategy to assess the metabolic effects of selective activation of a G(q)-coupled receptor in hepatocytes in vivo.
Li JH, Jain S, McMillin SM, Cui Y, Gautam D, Sakamoto W, Lu H, Jou W, McGuinness OP, Gavrilova O, Wess J
(2013) Endocrinology 154: 3539-51
MeSH Terms: Animals, Antidiuretic Hormone Receptor Antagonists, Cells, Cultured, Diabetes Mellitus, Type 2, Enzyme Activators, Female, G-Protein-Coupled Receptor Kinases, GTP-Binding Protein alpha Subunits, Gq-G11, Gluconeogenesis, Glycogenolysis, Hepatocytes, Humans, Hypoglycemic Agents, Male, Mice, Mice, Obese, Mice, Transgenic, Protein Engineering, Protein Interaction Domains and Motifs, Receptor, Muscarinic M3, Receptors, Vasopressin, Recombinant Fusion Proteins, Specific Pathogen-Free Organisms
Added July 21, 2014
1 Communities
1 Members
1 Resources
23 MeSH Terms
Engineering visual arrestin-1 with special functional characteristics.
Vishnivetskiy SA, Chen Q, Palazzo MC, Brooks EK, Altenbach C, Iverson TM, Hubbell WL, Gurevich VV
(2013) J Biol Chem 288: 3394-405
MeSH Terms: Animals, Arrestins, Eye, HEK293 Cells, Humans, Mice, Models, Molecular, Mutant Proteins, Mutation, Phosphates, Protein Binding, Protein Engineering, Protein Stability, Protein Structure, Tertiary, Rhodopsin, Static Electricity, Temperature, beta-Arrestins
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Synthetic biology with surgical precision: targeted reengineering of signaling proteins.
Gurevich VV, Gurevich EV
(2012) Cell Signal 24: 1899-908
MeSH Terms: Animals, Arrestin, Humans, Mitogen-Activated Protein Kinases, Models, Molecular, Protein Engineering, Proteins, Receptors, G-Protein-Coupled, Signal Transduction, Synthetic Biology
Added December 10, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Potential of fragment recombination for rational design of proteins.
Eisenbeis S, Proffitt W, Coles M, Truffault V, Shanmugaratnam S, Meiler J, Höcker B
(2012) J Am Chem Soc 134: 4019-22
MeSH Terms: Computational Biology, Computer Simulation, Models, Molecular, Protein Engineering, Protein Folding, Proteins
Added January 24, 2015
1 Communities
1 Members
0 Resources
6 MeSH Terms
Design of native-like proteins through an exposure-dependent environment potential.
DeLuca S, Dorr B, Meiler J
(2011) Biochemistry 50: 8521-8
MeSH Terms: Amino Acid Sequence, Computational Biology, Models, Molecular, Molecular Sequence Data, Protein Engineering, Proteins
Added January 24, 2015
1 Communities
1 Members
0 Resources
6 MeSH Terms
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation.
Panizzi P, Nahrendorf M, Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R
(2011) Nat Med 17: 1142-6
MeSH Terms: Animals, Coagulase, Endocarditis, Bacterial, Mice, Microscopy, Fluorescence, Positron-Emission Tomography, Protein Engineering, Prothrombin, Quorum Sensing, Staphylococcus aureus
Added January 20, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms