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Results: 11 to 15 of 15

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A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin.
Goswami S, Yee SW, Xu F, Sridhar SB, Mosley JD, Takahashi A, Kubo M, Maeda S, Davis RL, Roden DM, Hedderson MM, Giacomini KM, Savic RM
(2016) Clin Pharmacol Ther 100: 537-547
MeSH Terms: Adult, Aged, Aged, 80 and over, Diabetes Mellitus, Type 2, Disease Progression, Female, Glycated Hemoglobin A, Humans, Hypoglycemic Agents, Longitudinal Studies, Male, Membrane Proteins, Metformin, Middle Aged, Nonlinear Dynamics, Organic Cation Transport Proteins, Organic Cation Transporter 2, Pharmacogenomic Variants, Polymorphism, Single Nucleotide, Tumor Suppressor Proteins, Young Adult
Added March 24, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy.
Feng Q, Wei WQ, Chung CP, Levinson RT, Bastarache L, Denny JC, Stein CM
(2017) Pharmacogenomics J 17: 204-208
MeSH Terms: Adult, African Americans, Aged, Biomarkers, Cholesterol, LDL, Dyslipidemias, Female, Gene Frequency, Genetic Association Studies, Genotype, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Male, Middle Aged, Pharmacogenetics, Pharmacogenomic Variants, Phenotype, Polymorphism, Single Nucleotide, Proprotein Convertase 9, Risk Factors, Treatment Outcome, Whites
Added March 14, 2018
0 Communities
1 Members
0 Resources
22 MeSH Terms
Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.
Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, Weiss ST, Kroetz DL, Sadee W, Nickerson DA, Krauss RM, George AL, Schuetz EG, Medina MW, Cox NJ, Scherer SE, Giacomini KM, Brenner SE
(2017) Pharmacogenomics J 17: 137-145
MeSH Terms: Adipose Tissue, Alternative Splicing, Cell Line, Computational Biology, Databases, Genetic, Genotype, High-Throughput Nucleotide Sequencing, Humans, Kidney, Liver, Myocardium, Pharmacogenetics, Pharmacogenomic Variants, Phenotype, Sequence Analysis, RNA, Transcriptome
Added February 22, 2016
0 Communities
2 Members
0 Resources
16 MeSH Terms
Attitudes of clinicians following large-scale pharmacogenomics implementation.
Peterson JF, Field JR, Shi Y, Schildcrout JS, Denny JC, McGregor TL, Van Driest SL, Pulley JM, Lubin IM, Laposata M, Roden DM, Clayton EW
(2016) Pharmacogenomics J 16: 393-8
MeSH Terms: Adult, Aged, Attitude of Health Personnel, Drug-Related Side Effects and Adverse Reactions, Female, Genotype, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Perception, Pharmacogenetics, Pharmacogenomic Testing, Pharmacogenomic Variants, Phenotype, Physicians, Precision Medicine, Predictive Value of Tests, Risk Assessment, Risk Factors, Surveys and Questionnaires, Young Adult
Added April 11, 2017
0 Communities
3 Members
0 Resources
22 MeSH Terms
Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits.
Maranville JC, Cox NJ
(2016) Pharmacogenomics J 16: 388-92
MeSH Terms: Databases, Genetic, Drug-Related Side Effects and Adverse Reactions, Endophenotypes, Genetic Linkage, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Heredity, Humans, Pharmacogenomic Variants, Phenotype, Quantitative Trait, Heritable
Added February 22, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms