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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 76

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Biomarkers of response to Akt inhibitor MK-2206 in breast cancer.
Sangai T, Akcakanat A, Chen H, Tarco E, Wu Y, Do KA, Miller TW, Arteaga CL, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F
(2012) Clin Cancer Res 18: 5816-28
MeSH Terms: Animals, Apoptosis, Biomarkers, Pharmacological, Breast Neoplasms, Cell Line, Tumor, Class I Phosphatidylinositol 3-Kinases, Drug Synergism, Female, Heterocyclic Compounds, 3-Ring, Humans, In Vitro Techniques, Mice, Oncogene Protein v-akt, PTEN Phosphohydrolase, Paclitaxel, Phosphatidylinositol 3-Kinases, Protein Kinase Inhibitors, Transplantation, Heterologous
Added September 3, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Intensity-modulated radiation therapy with concurrent carboplatin and paclitaxel for locally advanced head and neck cancer: toxicities and efficacy.
Vlacich G, Diaz R, Thorpe SW, Murphy BA, Kirby W, Sinard RJ, Shakhtour B, Shyr Y, Murphy P, Netterville JL, Yarbrough WG, Cmelak AJ
(2012) Oncologist 17: 673-81
MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Squamous Cell, Chemoradiotherapy, Disease-Free Survival, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Paclitaxel, Radiotherapy Dosage, Radiotherapy, Intensity-Modulated, Randomized Controlled Trials as Topic, Retrospective Studies, Squamous Cell Carcinoma of Head and Neck, Treatment Outcome
Added March 10, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.
Njiaju UO, Gamazon ER, Gorsic LK, Delaney SM, Wheeler HE, Im HK, Dolan ME
(2012) Pharmacogenet Genomics 22: 498-507
MeSH Terms: Cell Line, Tumor, Genome, Human, Genotype, HapMap Project, Humans, Membrane Transport Proteins, Paclitaxel, Polymorphism, Single Nucleotide, RNA Interference
Added April 13, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).
Shajahan AN, Dobbin ZC, Hickman FE, Dakshanamurthy S, Clarke R
(2012) J Biol Chem 287: 17682-17692
MeSH Terms: Amino Acid Substitution, Antineoplastic Agents, Phytogenic, Apoptosis, Breast Neoplasms, Caveolin 1, Cell Line, Tumor, Cell Survival, Drug Resistance, Neoplasm, Female, Humans, MAP Kinase Kinase 4, Mitochondria, Mutation, Missense, Paclitaxel, Phosphorylation, Protein Structure, Tertiary, bcl-X Protein
Added August 14, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
BEAM: a randomized phase II study evaluating the activity of bevacizumab in combination with carboplatin plus paclitaxel in patients with previously untreated advanced melanoma.
Kim KB, Sosman JA, Fruehauf JP, Linette GP, Markovic SN, McDermott DF, Weber JS, Nguyen H, Cheverton P, Chen D, Peterson AC, Carson WE, O'Day SJ
(2012) J Clin Oncol 30: 34-41
MeSH Terms: Adult, Aged, Aged, 80 and over, Angiogenesis Inhibitors, Antibodies, Monoclonal, Humanized, Antineoplastic Combined Chemotherapy Protocols, Bevacizumab, Carboplatin, Double-Blind Method, Drug Administration Schedule, Female, Humans, Infusions, Intravenous, Kaplan-Meier Estimate, Male, Melanoma, Middle Aged, Paclitaxel, Skin Neoplasms, Treatment Outcome
Added March 20, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy.
Atuegwu NC, Arlinghaus LR, Li X, Welch EB, Chakravarthy BA, Gore JC, Yankeelov TE
(2011) Magn Reson Med 66: 1689-96
MeSH Terms: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Cell Survival, Chemotherapy, Adjuvant, Cisplatin, Computer Simulation, Diffusion Magnetic Resonance Imaging, Drug Therapy, Computer-Assisted, Everolimus, Female, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Middle Aged, Models, Biological, Paclitaxel, Prognosis, Reproducibility of Results, Sensitivity and Specificity, Sirolimus, Systems Integration, Treatment Outcome
Added November 13, 2013
0 Communities
4 Members
0 Resources
24 MeSH Terms
Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival.
Adams S, Chakravarthy AB, Donach M, Spicer D, Lymberis S, Singh B, Bauer JA, Hochman T, Goldberg JD, Muggia F, Schneider RJ, Pietenpol JA, Formenti SC
(2010) Breast Cancer Res Treat 124: 723-32
MeSH Terms: Adult, Antineoplastic Agents, Phytogenic, Breast Neoplasms, Chemotherapy, Adjuvant, Chi-Square Distribution, Disease-Free Survival, Drug Administration Schedule, Female, Humans, Kaplan-Meier Estimate, Lymphatic Metastasis, Mastectomy, Middle Aged, Neoadjuvant Therapy, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Neoplasm Staging, Paclitaxel, Proportional Hazards Models, Prospective Studies, Radiotherapy Dosage, Radiotherapy, Adjuvant, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome, United States
Added March 10, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.
Bauer JA, Ye F, Marshall CB, Lehmann BD, Pendleton CS, Shyr Y, Arteaga CL, Pietenpol JA
(2010) Breast Cancer Res 12: R41
MeSH Terms: Antineoplastic Agents, Phytogenic, Biomarkers, Tumor, Breast Neoplasms, Cell Line, Tumor, Drug Resistance, Neoplasm, Drug Synergism, Female, Humans, Neoplasms, Basal Cell, Paclitaxel, RNA Interference, RNA, Small Interfering
Added November 13, 2013
1 Communities
5 Members
0 Resources
12 MeSH Terms
Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.
Passarella RJ, Spratt DE, van der Ende AE, Phillips JG, Wu H, Sathiyakumar V, Zhou L, Hallahan DE, Harth E, Diaz R
(2010) Cancer Res 70: 4550-9
MeSH Terms: Animals, Antineoplastic Agents, Phytogenic, Apoptosis, Bacteriophages, Breast Neoplasms, Cell Growth Processes, Cell Line, Tumor, Coculture Techniques, Delayed-Action Preparations, Drug Delivery Systems, Endoplasmic Reticulum Chaperone BiP, Endothelial Cells, Glioma, Heat-Shock Proteins, Humans, Mice, Mice, Inbred C57BL, Mice, Nude, Nanoparticles, Oligopeptides, Paclitaxel, Recombinant Proteins, Xenograft Model Antitumor Assays
Added February 15, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Surgery with or without preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer: Southwest Oncology Group Trial S9900, an intergroup, randomized, phase III trial.
Pisters KM, Vallières E, Crowley JJ, Franklin WA, Bunn PA, Ginsberg RJ, Putnam JB, Chansky K, Gandara D
(2010) J Clin Oncol 28: 1843-9
MeSH Terms: Adenocarcinoma, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Large Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Combined Modality Therapy, Female, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paclitaxel, Survival Rate, Thoracic Surgery, Treatment Outcome
Added March 27, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms