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Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Blocking Zebrafish MicroRNAs with Morpholinos.
Flynt AS, Rao M, Patton JG
(2017) Methods Mol Biol 1565: 59-78
MeSH Terms: Animals, Electroporation, Gene Expression Regulation, Gene Silencing, Gene Transfer Techniques, MicroRNAs, Microinjections, Morpholinos, Oligonucleotides, Antisense, Retina, Zebrafish
Added August 4, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms
Ion Mobility Collision Cross Section Compendium.
May JC, Morris CB, McLean JA
(2017) Anal Chem 89: 1032-1044
MeSH Terms: Animals, Gases, Humans, Inorganic Chemicals, Ions, Lipids, Mass Spectrometry, Nucleotides, Proteins
Added December 17, 2018
1 Communities
1 Members
0 Resources
9 MeSH Terms
Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.
Patra A, Zhang Q, Guengerich FP, Egli M
(2016) J Biol Chem 291: 24304-24313
MeSH Terms: Bacterial Proteins, Crystallography, X-Ray, DNA, DNA Polymerase beta, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Humans, Sulfolobus solfataricus, Thymine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι.
Choi JY, Patra A, Yeom M, Lee YS, Zhang Q, Egli M, Guengerich FP
(2016) J Biol Chem 291: 21063-21073
MeSH Terms: Amino Acid Substitution, Crystallography, X-Ray, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Humans, Hydrogen Bonding, Kinetics, Magnesium, Manganese, Mutation, Missense, Protein Domains
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Horizontally acquired genes in early-diverging pathogenic fungi enable the use of host nucleosides and nucleotides.
Alexander WG, Wisecaver JH, Rokas A, Hittinger CT
(2016) Proc Natl Acad Sci U S A 113: 4116-21
MeSH Terms: Fungi, Gene Transfer, Horizontal, Genes, Fungal, Host-Pathogen Interactions, Nucleosides, Nucleotides, Phylogeny
Added April 6, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms
Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η.
Su Y, Egli M, Guengerich FP
(2016) J Biol Chem 291: 3747-56
MeSH Terms: Crystallography, X-Ray, DNA, DNA-Directed DNA Polymerase, Humans, Protein Structure, Tertiary, Ribonucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η.
Xue Q, Zhong M, Liu B, Tang Y, Wei Z, Guengerich FP, Zhang H
(2016) Biochimie 121: 161-9
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Catalytic Domain, DNA-Directed DNA Polymerase, Deoxyguanosine, Kinetics, Pyrimidine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).
Zhu L, McDavid S, Currie KP
(2015) PLoS One 10: e0134117
MeSH Terms: Animals, Calcium Channel Blockers, Calcium Channels, N-Type, Calcium Signaling, Cattle, Cells, Cultured, Chromaffin Cells, Enzyme Activation, Guanosine Diphosphate, HEK293 Cells, Humans, Kinetics, Patch-Clamp Techniques, Protein Kinase C, Recombinant Proteins, Tetradecanoylphorbol Acetate, Thionucleotides
Added November 10, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Polymerase Bypass of N(6)-Deoxyadenosine Adducts Derived from Epoxide Metabolites of 1,3-Butadiene.
Kotapati S, Wickramaratne S, Esades A, Boldry EJ, Quirk Dorr D, Pence MG, Guengerich FP, Tretyakova NY
(2015) Chem Res Toxicol 28: 1496-507
MeSH Terms: Butadienes, Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Epoxy Compounds, Humans, Kinetics, Oligodeoxyribonucleotides, Spectrometry, Mass, Electrospray Ionization
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms