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Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA.
Seth PP, Yu J, Jazayeri A, Pallan PS, Allerson CR, Østergaard ME, Liu F, Herdewijn P, Egli M, Swayze EE
(2012) J Org Chem 77: 5074-85
MeSH Terms: Catalysis, Crystallography, X-Ray, Cyclohexenes, Models, Molecular, Molecular Structure, Nucleic Acid Conformation, Nucleic Acids, Oligonucleotides, RNA, Sugar Alcohols
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides.
Egli M, Pallan PS, Allerson CR, Prakash TP, Berdeja A, Yu J, Lee S, Watt A, Gaus H, Bhat B, Swayze EE, Seth PP
(2011) J Am Chem Soc 133: 16642-9
MeSH Terms: Models, Molecular, Molecular Conformation, Nucleic Acids, Oligonucleotides, RNA, Stereoisomerism, Sugar Alcohols
Added March 7, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Design, synthesis, and characterization of nucleic-acid-functionalized gold surfaces for biomarker detection.
Adams NM, Jackson SR, Haselton FR, Wright DW
(2012) Langmuir 28: 1068-82
MeSH Terms: Biomarkers, Cell Line, DNA Barcoding, Taxonomic, Gold, Humans, Metal Nanoparticles, Microscopy, Fluorescence, Nucleic Acids, Surface Properties
Added May 27, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Use of chromophoric ligands to visually screen co-crystals of putative protein-nucleic acid complexes.
Jiang X, Egli M
(2011) Curr Protoc Nucleic Acid Chem Chapter 7: Unit 7.15.1-8
MeSH Terms: Carbocyanines, Crystallization, DNA Primers, DNA-Directed DNA Polymerase, Electrophoresis, Fluorescent Dyes, Gentian Violet, Ligands, Nucleic Acids, Oligonucleotides, Proteins, Solutions
Added March 7, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Thiol-based, site-specific and covalent immobilization of biomolecules for single-molecule experiments.
Zimmermann JL, Nicolaus T, Neuert G, Blank K
(2010) Nat Protoc 5: 975-85
MeSH Terms: Binding Sites, Enzymes, Immobilized, Fluorescence, Immobilized Proteins, Maleimides, Microscopy, Atomic Force, Nucleic Acids, Polyethylene Glycols, Succinimides, Sulfhydryl Compounds
Added June 2, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Crystallographic studies of chemically modified nucleic acids: a backward glance.
Egli M, Pallan PS
(2010) Chem Biodivers 7: 60-89
MeSH Terms: Base Pairing, Bridged Bicyclo Compounds, Carbohydrates, Crystallography, X-Ray, Molecular Conformation, Nucleic Acids, Nucleotides, Sulfhydryl Compounds
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Tart cherry juice decreases oxidative stress in healthy older men and women.
Traustadóttir T, Davies SS, Stock AA, Su Y, Heward CB, Roberts LJ, Harman SM
(2009) J Nutr 139: 1896-900
MeSH Terms: Aged, Beverages, Cross-Over Studies, Fatty Acids, Unsaturated, Female, Fruit, Humans, Isoprostanes, Male, Middle Aged, Nucleic Acids, Oxidative Stress, Prunus
Added June 1, 2013
2 Communities
1 Members
0 Resources
13 MeSH Terms
Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing.
Pallan PS, Lubini P, Bolli M, Egli M
(2007) Nucleic Acids Res 35: 6611-24
MeSH Terms: Base Pairing, DNA, Models, Molecular, Peptide Nucleic Acids, RNA, Thermodynamics
Added March 5, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Selenium modification of nucleic acids: preparation of oligonucleotides with incorporated 2'-SeMe-uridine for crystallographic phasing of nucleic acid structures.
Pallan PS, Egli M
(2007) Nat Protoc 2: 647-51
MeSH Terms: Chromatography, High Pressure Liquid, Crystallography, Molecular Structure, Nucleic Acids, Oligonucleotide Probes, Selenomethionine, Uridine
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Selenium modification of nucleic acids: preparation of phosphoroselenoate derivatives for crystallographic phasing of nucleic acid structures.
Pallan PS, Egli M
(2007) Nat Protoc 2: 640-6
MeSH Terms: Chromatography, High Pressure Liquid, Crystallography, Molecular Structure, Nucleic Acids, Phosphorus Compounds, Selenium, Selenium Compounds
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms