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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 34

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NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.
Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR, Segal BH
(2013) J Immunol 190: 1714-24
MeSH Terms: Acute Lung Injury, Animals, Cell Line, Tumor, Disease Models, Animal, Human Umbilical Vein Endothelial Cells, Humans, Inflammation Mediators, Intubation, Intratracheal, Male, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, NADPH Oxidases, NF-E2-Related Factor 2, Neutrophil Infiltration, Neutrophils
Added March 13, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury.
Nlandu Khodo S, Dizin E, Sossauer G, Szanto I, Martin PY, Feraille E, Krause KH, de Seigneux S
(2012) J Am Soc Nephrol 23: 1967-76
MeSH Terms: Animals, Antioxidants, Apoptosis, Atrophy, Capillaries, Fibrosis, Hypoxia-Inducible Factor 1, alpha Subunit, Kidney, Kidney Diseases, Male, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Mice, Knockout, NADPH Oxidase 2, NADPH Oxidase 4, NADPH Oxidases, NF-E2-Related Factor 2, Oxidative Stress, Ureteral Obstruction, Vascular Endothelial Growth Factor A
Added December 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Loss of Nrf2 accelerates ionizing radiation-induced bone loss by upregulating RANKL.
Rana T, Schultz MA, Freeman ML, Biswas S
(2012) Free Radic Biol Med 53: 2298-307
MeSH Terms: Animals, Bone Marrow Cells, Cell Survival, Mice, Mice, Knockout, NF-E2-Related Factor 2, Osteoblasts, Osteoclasts, Osteoporosis, Oxidative Stress, RANK Ligand, Radiation Injuries, Experimental, Radiation Tolerance, Skull, Tibia, Up-Regulation
Added March 13, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis.
Hou Y, Xue P, Bai Y, Liu D, Woods CG, Yarborough K, Fu J, Zhang Q, Sun G, Collins S, Chan JY, Yamamoto M, Andersen ME, Pi J
(2012) Free Radic Biol Med 52: 462-72
MeSH Terms: 1-Methyl-3-isobutylxanthine, 3T3-L1 Cells, Adaptor Proteins, Signal Transducing, Adipogenesis, Animals, Antioxidants, CCAAT-Enhancer-Binding Protein-beta, Cell Nucleus, Cytoskeletal Proteins, Dexamethasone, Female, Gene Expression Regulation, Gene Knockdown Techniques, Genes, Reporter, Insulin, Kelch-Like ECH-Associated Protein 1, Luciferases, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-E2-Related Factor 2, Oxidative Stress, Primary Cell Culture, Reactive Oxygen Species, Response Elements, Transcription, Genetic
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
NRF2 deficiency reduces life span of mice administered thoracic irradiation.
Travis EL, Rachakonda G, Zhou X, Korhonen K, Sekhar KR, Biswas S, Freeman ML
(2011) Free Radic Biol Med 51: 1175-83
MeSH Terms: Animals, Fibroblasts, Humans, Lung, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-E2-Related Factor 2, Oxidation-Reduction, Plasminogen Activator Inhibitor 1, Radiation Injuries, Experimental, Radiation Pneumonitis, Radiation, Ionizing, Radiotherapy, S100 Calcium-Binding Protein A4, S100 Proteins, Signal Transduction, Transforming Growth Factor beta
Added March 13, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Loss of NRF2 impairs gastric nitrergic stimulation and function.
Mukhopadhyay S, Sekhar KR, Hale AB, Channon KM, Farrugia G, Freeman ML, Gangula PR
(2011) Free Radic Biol Med 51: 619-25
MeSH Terms: Animals, Antioxidants, Biopterin, Chloramphenicol O-Acetyltransferase, Disease Models, Animal, Down-Regulation, Gastric Emptying, Gastric Mucosa, Gastroparesis, Glutamate-Cysteine Ligase, Humans, Mice, Mice, Knockout, Muscle Relaxation, NF-E2-Related Factor 2, Nitrergic Neurons, Stomach, Superoxide Dismutase, Superoxide Dismutase-1, Vasomotor System
Added March 13, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivo.
Dworski R, Han W, Blackwell TS, Hoskins A, Freeman ML
(2011) Free Radic Biol Med 51: 516-21
MeSH Terms: Adult, Allergens, Asthma, Female, Humans, Macrophages, Alveolar, Male, NF-E2-Related Factor 2, Vitamin E
Added March 5, 2014
1 Communities
2 Members
0 Resources
9 MeSH Terms
Age-related retinopathy in NRF2-deficient mice.
Zhao Z, Chen Y, Wang J, Sternberg P, Freeman ML, Grossniklaus HE, Cai J
(2011) PLoS One 6: e19456
MeSH Terms: Aging, Animals, Antioxidants, Electroretinography, Immunohistochemistry, Inflammation, Lipofuscin, Lysosomes, Mice, Mice, Inbred C57BL, Mice, Transgenic, NF-E2-Related Factor 2, Phenotype, Retinal Diseases, Time Factors
Added March 7, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
Increased cell migration and plasticity in Nrf2-deficient cancer cell lines.
Rachakonda G, Sekhar KR, Jowhar D, Samson PC, Wikswo JP, Beauchamp RD, Datta PK, Freeman ML
(2010) Oncogene 29: 3703-14
MeSH Terms: Cell Adhesion, Cell Line, Tumor, Cell Movement, Cell Survival, Humans, Inverted Repeat Sequences, NF-E2-Related Factor 2, Neoplasms, Phosphorylation, RNA Interference, RNA, Small Interfering, Reactive Oxygen Species, Smad Proteins, Transcription, Genetic, ras Proteins
Added May 3, 2013
1 Communities
4 Members
0 Resources
15 MeSH Terms
NADPH oxidase limits innate immune responses in the lungs in mice.
Segal BH, Han W, Bushey JJ, Joo M, Bhatti Z, Feminella J, Dennis CG, Vethanayagam RR, Yull FE, Capitano M, Wallace PK, Minderman H, Christman JW, Sporn MB, Chan J, Vinh DC, Holland SM, Romani LR, Gaffen SL, Freeman ML, Blackwell TS
(2010) PLoS One 5: e9631
MeSH Terms: Animals, Cytokines, Gene Expression Regulation, Enzymologic, Granulomatous Disease, Chronic, Immunity, Innate, Inflammation, Lung, Macrophages, Membrane Glycoproteins, Mice, NADPH Oxidase 2, NADPH Oxidases, NF-E2-Related Factor 2, NF-kappa B, Oxidation-Reduction
Added February 26, 2013
2 Communities
3 Members
0 Resources
15 MeSH Terms