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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 144

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In Silico Pharmacoepidemiologic Evaluation of Drug-Induced Cardiovascular Complications Using Combined Classifiers.
Cai C, Fang J, Guo P, Wang Q, Hong H, Moslehi J, Cheng F
(2018) J Chem Inf Model 58: 943-956
MeSH Terms: Antineoplastic Agents, Cardiovascular System, Computational Biology, Computer Simulation, Drug Discovery, Drug-Related Side Effects and Adverse Reactions, Humans, Molecular Targeted Therapy, Myocytes, Cardiac, Pluripotent Stem Cells, Product Surveillance, Postmarketing, Safety
Added October 1, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
Bergmeijer TO, Reny JL, Pakyz RE, Gong L, Lewis JP, Kim EY, Aradi D, Fernandez-Cadenas I, Horenstein RB, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman RB, Alexopoulos D, Kim HS, Déry JP, Gawaz M, Bliden K, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Simon T, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Hulot JS, Mitchell BD, Schwab M, Ritchie MD, Klein TE, Shuldiner AR, ICPC Investigators
(2018) Am Heart J 198: 152-159
MeSH Terms: Acute Coronary Syndrome, Aged, Clopidogrel, Female, Genetic Association Studies, Genome-Wide Association Study, Humans, Internationality, Male, Middle Aged, Molecular Targeted Therapy, Pharmacogenetics, Prognosis, Receptors, Purinergic P2Y12, Risk Assessment, Survival Rate, Treatment Outcome
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Macrophage-Targeted Therapeutics for Metabolic Disease.
Peterson KR, Cottam MA, Kennedy AJ, Hasty AH
(2018) Trends Pharmacol Sci 39: 536-546
MeSH Terms: Drug Delivery Systems, Gene Expression, Humans, Macrophages, Metabolic Diseases, Molecular Targeted Therapy, Pharmaceutical Preparations
Added March 26, 2019
0 Communities
1 Members
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MeSH Terms
Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.
Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ, Fusion Analysis Working Group, Cancer Genome Atlas Research Network, Chen K, Lazar AJ, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L
(2018) Cell Rep 23: 227-238.e3
MeSH Terms: Antineoplastic Agents, Carcinogenesis, Cell Line, Tumor, Humans, Molecular Targeted Therapy, Neoplasms, Oncogene Fusion, Oncogene Proteins, Fusion
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Autochthonous tumors driven by loss have an ongoing requirement for the RBP2 histone demethylase.
McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG
(2018) Proc Natl Acad Sci U S A 115: E3741-E3748
MeSH Terms: Alleles, Animals, DNA-Binding Proteins, Echocardiography, Enzyme Activation, Fibroblasts, Genes, Retinoblastoma, Heart Septal Defects, Histone Code, Integrases, Jumonji Domain-Containing Histone Demethylases, Mice, Mice, Inbred C57BL, Molecular Targeted Therapy, Neoplasm Proteins, Pituitary Neoplasms, Recombinant Fusion Proteins, Retinoblastoma Protein, Tamoxifen, Thyroid Neoplasms, Transgenes
Added April 22, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
A Nonquiescent "Idling" Population State in Drug-Treated, BRAF-Mutated Melanoma.
Paudel BB, Harris LA, Hardeman KN, Abugable AA, Hayford CE, Tyson DR, Quaranta V
(2018) Biophys J 114: 1499-1511
MeSH Terms: Cell Line, Tumor, Drug Resistance, Neoplasm, Epigenesis, Genetic, Humans, Melanoma, Molecular Targeted Therapy, Mutation, Proto-Oncogene Proteins B-raf
Added April 15, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M Muscarinic Receptor as a Novel Therapeutic Target.
Gogliotti RG, Fisher NM, Stansley BJ, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2018) J Pharmacol Exp Ther 365: 291-300
MeSH Terms: Animals, Autopsy, Cerebellum, Humans, Mice, Molecular Targeted Therapy, Motor Cortex, Receptor, Muscarinic M4, Rett Syndrome, Sequence Analysis, RNA
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
Mechanisms of receptor tyrosine kinase activation in cancer.
Du Z, Lovly CM
(2018) Mol Cancer 17: 58
MeSH Terms: Animals, Cell Transformation, Neoplastic, Enzyme Activation, Gene Expression Regulation, Neoplastic, Humans, Ligands, Molecular Targeted Therapy, Mutation, Neoplasms, Phosphorylation, Protein Binding, Protein Interaction Domains and Motifs, Protein Kinase Inhibitors, Protein Multimerization, Receptor Protein-Tyrosine Kinases, Signal Transduction
Added September 10, 2020
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1 Members
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MeSH Terms
The Clinical Presentation, Survival Outcomes, and Management of Patients With Renal Cell Carcinoma and Cardiac Metastasis Without Inferior Vena Cava Involvement: Results From a Pooled Clinical Trial Database and Systematic Review of Reported Cases.
Viteri Malone MA, Ares GR, De Velasco G, Brandão R, Lin X, Norton C, Simantov R, Moslehi J, Krajewski KM, Choueiri TK, McKay RR
(2018) Clin Genitourin Cancer 16: e327-e333
MeSH Terms: Adult, Aged, Carcinoma, Renal Cell, Clinical Trials as Topic, Female, Heart Neoplasms, Humans, Kidney Neoplasms, Male, Middle Aged, Molecular Targeted Therapy, Progression-Free Survival, Retrospective Studies, Survival Analysis, Treatment Outcome, Vena Cava, Inferior
Added April 22, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
Established, emerging and elusive molecular targets in the treatment of lung cancer.
Gallant JN, Lovly CM
(2018) J Pathol 244: 565-577
MeSH Terms: Animals, Antineoplastic Agents, Biomarkers, Tumor, Clinical Decision-Making, Genetic Predisposition to Disease, Genomics, Humans, Lung Neoplasms, Molecular Targeted Therapy, Pathology, Molecular, Phenotype, Precision Medicine, Predictive Value of Tests, Prognosis
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms