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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 358

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Cystitis and Struvite Urolithiasis in Nude Mice Implanted with Sustained-release Estrogen Pellets.
Salleng KJ, Jones CP, Boyd KL, Hicks DJ, Williams MM, Cook RS
(2018) Comp Med 68: 256-260
MeSH Terms: Animals, Cystitis, Estrogens, Female, Humans, MCF-7 Cells, Mice, Mice, Nude, Staphylococcus, Struvite, Urolithiasis
Added April 15, 2019
0 Communities
1 Members
0 Resources
11 MeSH Terms
Quantitative in vivo whole genome motility screen reveals novel therapeutic targets to block cancer metastasis.
Stoletov K, Willetts L, Paproski RJ, Bond DJ, Raha S, Jovel J, Adam B, Robertson AE, Wong F, Woolner E, Sosnowski DL, Bismar TA, Wong GK, Zijlstra A, Lewis JD
(2018) Nat Commun 9: 2343
MeSH Terms: Animals, Cell Line, Tumor, Cell Movement, Chick Embryo, Collagen, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Male, Mice, Mice, Nude, Mice, SCID, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasm Transplantation, Phenotype, Prostatic Neoplasms, RNA Interference, RNA, Small Interfering
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
The BET inhibitor INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.
Wilson AJ, Stubbs M, Liu P, Ruggeri B, Khabele D
(2018) Gynecol Oncol 149: 575-584
MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, BRCA1 Protein, Carcinoma, Ovarian Epithelial, Cell Cycle Proteins, Cell Line, Tumor, Down-Regulation, Drug Synergism, Female, Homologous Recombination, Humans, Indoles, Mice, Mice, Inbred NOD, Mice, Nude, Mice, SCID, Neoplasms, Glandular and Epithelial, Nuclear Proteins, Organic Chemicals, Ovarian Neoplasms, Phthalazines, Piperazines, Poly(ADP-ribose) Polymerase Inhibitors, Transcription Factors, Xenograft Model Antitumor Assays
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL
(2018) Cancer Res 78: 1845-1858
MeSH Terms: Animals, Antineoplastic Agents, Cell Proliferation, Cell Survival, Disease Models, Animal, Female, Humans, Lapatinib, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred BALB C, Mice, Nude, Nanoparticles, Protein Kinase Inhibitors, RNA, Small Interfering, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.
Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL
(2017) Cell Metab 26: 633-647.e7
MeSH Terms: Animals, Cell Line, Tumor, Drug Resistance, Neoplasm, Female, Humans, Mice, Nude, Mitochondria, Myeloid Cell Leukemia Sequence 1 Protein, Neoplastic Stem Cells, Oxidative Phosphorylation, Proto-Oncogene Proteins c-myc, Reactive Oxygen Species, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ
(2017) Sci Signal 10:
MeSH Terms: Animals, Antineoplastic Agents, Benzoates, Casein Kinase Ialpha, Enzyme Activation, Enzyme Activators, Gene Expression Regulation, Neoplastic, HCT116 Cells, Humans, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Nude, Neoplasm Metastasis, Neoplasms, Organ Culture Techniques, Phosphorylation, Pyrvinium Compounds, Signal Transduction, Surface Plasmon Resonance, Wnt Proteins, Wnt Signaling Pathway, Xenograft Model Antitumor Assays, Xenopus laevis
Added July 18, 2017
0 Communities
1 Members
0 Resources
24 MeSH Terms
High-resolution hyperpolarized in vivo metabolic C spectroscopy at low magnetic field (48.7mT) following murine tail-vein injection.
Coffey AM, Feldman MA, Shchepin RV, Barskiy DA, Truong ML, Pham W, Chekmenev EY
(2017) J Magn Reson 281: 246-252
MeSH Terms: Animals, Carbon Isotopes, Cell Line, Tumor, Contrast Media, Electromagnetic Fields, Female, Injections, Intravenous, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Mice, Mice, Nude, Neoplasms, Experimental, Tail, Veins
Added March 21, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.
Song W, Hwang Y, Youngblood VM, Cook RS, Balko JM, Chen J, Brantley-Sieders DM
(2017) Oncogene 36: 5620-5630
MeSH Terms: Animals, Benzamides, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Cyclin-Dependent Kinase Inhibitor p27, Ephrin-A2, Female, Gene Knockdown Techniques, Humans, Mice, Mice, Inbred NOD, Mice, Nude, Mice, SCID, Neoplasm Recurrence, Local, Niacinamide, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-myb, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 14, 2018
0 Communities
2 Members
0 Resources
20 MeSH Terms
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.
Jackson MA, Werfel TA, Curvino EJ, Yu F, Kavanaugh TE, Sarett SM, Dockery MD, Kilchrist KV, Jackson AN, Giorgio TD, Duvall CL
(2017) ACS Nano 11: 5680-5696
MeSH Terms: Animals, Cell Line, Tumor, Drug Carriers, Female, Humans, Male, Mice, Nude, Nanostructures, Neoplasms, Phosphorylcholine, Polyethylene Glycols, Polymers, RNA, Small Interfering, RNAi Therapeutics, Surface Properties
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Myelin-Associated Glycoprotein Inhibits Schwann Cell Migration and Induces Their Death.
Chaudhry N, Bachelin C, Zujovic V, Hilaire M, Baldwin KT, Follis RM, Giger R, Carter BD, Baron-Van Evercooren A, Filbin MT
(2017) J Neurosci 37: 5885-5899
MeSH Terms: Animals, Apoptosis, Cell Movement, Cells, Cultured, Female, Mice, Mice, Nude, Myelin Sheath, Myelin-Associated Glycoprotein, Neuronal Outgrowth, Schwann Cells
Added March 21, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms