NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1.
Petkowski JJ, Bonsignore LA, Tooley JG, Wilkey DW, Merchant ML, Macara IG, Schaner Tooley CE
(2013) Biochem J 456
: 453-62MeSH Terms: Catalysis, HEK293 Cells, Humans, Methylation, Methyltransferases, Substrate SpecificityAdded March 7, 2014
6 MeSH Terms
Epigenomic plasticity enables human pancreatic α to β cell reprogramming.
Bramswig NC, Everett LJ, Schug J, Dorrell C, Liu C, Luo Y, Streeter PR, Naji A, Grompe M, Kaestner KH
(2013) J Clin Invest 123
: 1275-84MeSH Terms: Animals, Cell Differentiation, Cell Separation, Cells, Cultured, Enzyme Inhibitors, Epigenesis, Genetic, Flow Cytometry, Gene Expression Profiling, Glucagon-Secreting Cells, Histone Methyltransferases, Histone-Lysine N-Methyltransferase, Histones, Humans, Insulin-Secreting Cells, Methylation, Mice, Molecular Sequence Annotation, Protein Processing, Post-Translational, Sequence Analysis, RNA, TranscriptomeAdded June 5, 2013
20 MeSH Terms
Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT.
Petkowski JJ, Schaner Tooley CE, Anderson LC, Shumilin IA, Balsbaugh JL, Shabanowitz J, Hunt DF, Minor W, Macara IG
(2012) Biochemistry 51
: 5942-50MeSH Terms: Humans, Methylation, Methyltransferases, Peptide Fragments, Protein Binding, Protein Processing, Post-Translational, Substrate SpecificityAdded March 20, 2014
7 MeSH Terms
Gender specific differences in bladder cancer.
DeGraff DJ, Matusik RJ
(2012) J Urol 188
: 10-1MeSH Terms: Adenosine, Animals, Gene Expression Regulation, Neoplastic, Humans, Male, Methyltransferases, Prostatic Neoplasms, RNA, Neoplasm, Receptors, AndrogenAdded November 28, 2012
9 MeSH Terms
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Okada Y, Kubo M, Ohmiya H, Takahashi A, Kumasaka N, Hosono N, Maeda S, Wen W, Dorajoo R, Go MJ, Zheng W, Kato N, Wu JY, Lu Q, GIANT consortium, Tsunoda T, Yamamoto K, Nakamura Y, Kamatani N, Tanaka T
(2012) Nat Genet 44
: 302-6MeSH Terms: Asians, Body Mass Index, Chromosomes, Human, Pair 6, Chromosomes, Human, Pair 9, Cyclin-Dependent Kinase 5, Far East, Genetic Variation, Genome-Wide Association Study, Genotype, Humans, Kruppel-Like Transcription Factors, Obesity, Polymorphism, Single Nucleotide, tRNA MethyltransferasesAdded June 26, 2014
14 MeSH Terms
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms.
Nes CR, Singha UK, Liu J, Ganapathy K, Villalta F, Waterman MR, Lepesheva GI, Chaudhuri M, Nes WD
(2012) Biochem J 443
: 267-77MeSH Terms: Escherichia coli, Metabolome, Methyltransferases, Protozoan Proteins, Recombinant Proteins, Sterol 14-Demethylase, Sterols, Trypanosoma brucei bruceiAdded February 12, 2015
8 MeSH Terms
Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.
Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L
(2011) Genes Dev 25
: 2291-305MeSH Terms: Animals, Cell Differentiation, Co-Repressor Proteins, DNA (Cytosine-5-)-Methyltransferases, DNA Methyltransferase 3A, Diabetes Mellitus, Gene Expression Regulation, Ghrelin, Glucagon, Glucagon-Secreting Cells, Homeobox Protein Nkx-2.2, Homeodomain Proteins, Insulin, Insulin-Secreting Cells, Mice, Mutation, Nuclear Proteins, Organ Specificity, Promoter Regions, Genetic, Protein Binding, Protein Structure, Tertiary, Proteins, Transcription Factors, Zebrafish ProteinsAdded September 3, 2013
24 MeSH Terms
NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein.
Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Sabat M, Minor W, Hunt DF, Macara IG
(2010) Nature 466
: 1125-8MeSH Terms: Cell Cycle Proteins, Cell Line, Chromosome Segregation, DNA-Binding Proteins, Gene Knockdown Techniques, Guanine Nucleotide Exchange Factors, HeLa Cells, Histone Chaperones, Humans, Methyltransferases, Models, Molecular, Mutation, Nuclear Proteins, Protein Binding, Protein Structure, Tertiary, Retinoblastoma Protein, Spindle Apparatus, Transcription FactorsAdded March 5, 2014
18 MeSH Terms
Two-stage case-control study of DNMT-1 and DNMT-3B gene variants and breast cancer risk.
Ye C, Beeghly-Fadiel A, Lu W, Long J, Shu XO, Gao YT, Zheng W, Cai Q
(2010) Breast Cancer Res Treat 121
: 765-9MeSH Terms: Asians, Breast Neoplasms, Case-Control Studies, China, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, Female, Genetic Predisposition to Disease, Humans, Polymorphism, Single Nucleotide, RiskAdded December 10, 2013
11 MeSH Terms
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.
Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA
(2008) Nat Struct Mol Biol 15
: 268-79MeSH Terms: Animals, Chromobox Protein Homolog 5, Chromosomal Proteins, Non-Histone, DEAD-box RNA Helicases, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, Endoribonucleases, Histones, Mice, MicroRNAs, Models, Biological, Recombination, Genetic, Retinoblastoma-Like Protein p130, Ribonuclease III, Telomerase, TelomereAdded January 30, 2013
17 MeSH Terms