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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 18 of 18

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Bortezomib augments lymphocyte stimulatory cytokine signaling in the tumor microenvironment to sustain CD8+T cell antitumor function.
Pellom ST, Dudimah DF, Thounaojam MC, Uzhachenko RV, Singhal A, Richmond A, Shanker A
(2017) Oncotarget 8: 8604-8621
MeSH Terms: Adenocarcinoma, Animals, Antineoplastic Agents, Bortezomib, Breast Neoplasms, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Cytokines, Female, Fibrosarcoma, Kidney Neoplasms, Lung Neoplasms, Lymphocytes, Tumor-Infiltrating, Mice, Inbred BALB C, Mice, Transgenic, Phosphatidylinositol 3-Kinase, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Proto-Oncogene Proteins c-akt, Receptors, Cytokine, STAT5 Transcription Factor, Signal Transduction, Tumor Escape, Tumor Microenvironment
Added March 14, 2017
2 Communities
1 Members
0 Resources
24 MeSH Terms
Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection.
Lehmann BD, Jovanović B, Chen X, Estrada MV, Johnson KN, Shyr Y, Moses HL, Sanders ME, Pietenpol JA
(2016) PLoS One 11: e0157368
MeSH Terms: Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Computational Biology, Datasets as Topic, Disease Progression, Female, Gene Expression, Gene Expression Profiling, Humans, Immunohistochemistry, Laser Capture Microdissection, Lymphocytes, Tumor-Infiltrating, Microarray Analysis, Neoadjuvant Therapy, Neoplasm Grading, Neoplasm Proteins, Retrospective Studies, Stromal Cells, Survival Analysis, Triple Negative Breast Neoplasms
Added April 9, 2017
1 Communities
2 Members
0 Resources
20 MeSH Terms
Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.
Vilgelm AE, Johnson CA, Prasad N, Yang J, Chen SC, Ayers GD, Pawlikowski JS, Raman D, Sosman JA, Kelley M, Ecsedy JA, Shyr Y, Levy SE, Richmond A
(2016) J Natl Cancer Inst 108: djv406
MeSH Terms: Animals, Aurora Kinase A, Cell Line, Tumor, Cellular Senescence, Chemokine CCL5, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Enzyme-Linked Immunosorbent Assay, Female, Flow Cytometry, Gene Expression Regulation, Neoplastic, Heterografts, Humans, Immunocompetence, Immunocompromised Host, Immunotherapy, Lymphocyte Activation, Lymphocytes, Tumor-Infiltrating, Melanoma, Mice, Real-Time Polymerase Chain Reaction, Skin Neoplasms, Transcriptome, Tumor Microenvironment, Tumor Necrosis Factor Receptor Superfamily, Member 9
Added January 18, 2016
2 Communities
3 Members
0 Resources
25 MeSH Terms
RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors.
Loi S, Dushyanthen S, Beavis PA, Salgado R, Denkert C, Savas P, Combs S, Rimm DL, Giltnane JM, Estrada MV, Sánchez V, Sanders ME, Cook RS, Pilkinton MA, Mallal SA, Wang K, Miller VA, Stephens PJ, Yelensky R, Doimi FD, Gómez H, Ryzhov SV, Darcy PK, Arteaga CL, Balko JM
(2016) Clin Cancer Res 22: 1499-509
MeSH Terms: Animals, B7-H1 Antigen, Biomarkers, Cell Line, Tumor, Disease Models, Animal, Disease Progression, Female, Gene Expression Profiling, Humans, Immunomodulation, Immunophenotyping, Lymphocytes, Tumor-Infiltrating, Mice, Mitogen-Activated Protein Kinases, Mortality, Phenotype, Programmed Cell Death 1 Receptor, Protein Kinase Inhibitors, Signal Transduction, Transcriptome, Triple Negative Breast Neoplasms, ras Proteins
Added April 6, 2017
1 Communities
2 Members
0 Resources
22 MeSH Terms
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression.
Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R
(2010) Proc Natl Acad Sci U S A 107: 12747-54
MeSH Terms: B-Lymphocytes, CD40 Antigens, Disease Progression, Enzyme Activation, Extracellular Space, Humans, Lymphocyte Subsets, Lymphocytes, Tumor-Infiltrating, Lymphoma, Follicular, Models, Immunological, Phenotype, Phosphoprotein Phosphatases, Prognosis, Receptors, Antigen, B-Cell, Reproducibility of Results, Signal Transduction, Survival Analysis
Added February 15, 2013
1 Communities
1 Members
0 Resources
17 MeSH Terms
Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells.
Irish JM, Czerwinski DK, Nolan GP, Levy R
(2006) Blood 108: 3135-42
MeSH Terms: B-Lymphocytes, Humans, Lymphocytes, Tumor-Infiltrating, Lymphoma, B-Cell, Lymphoma, Follicular, Receptors, Antigen, B-Cell, Signal Transduction
Added February 15, 2013
1 Communities
1 Members
0 Resources
7 MeSH Terms
Mechanisms of apoptosis in T cells from patients with renal cell carcinoma.
Uzzo RG, Rayman P, Kolenko V, Clark PE, Bloom T, Ward AM, Molto L, Tannenbaum C, Worford LJ, Bukowski R, Tubbs R, Hsi ED, Bander NH, Novick AC, Finke JH
(1999) Clin Cancer Res 5: 1219-29
MeSH Terms: Apoptosis, Blood Cells, Carcinoma, Renal Cell, DNA Fragmentation, Fas Ligand Protein, Humans, In Situ Nick-End Labeling, Ionomycin, Jurkat Cells, Kidney Neoplasms, Lymphocyte Activation, Lymphocytes, Tumor-Infiltrating, Membrane Glycoproteins, Muromonab-CD3, Neoplasm Proteins, Polymerase Chain Reaction, RNA, Messenger, RNA, Neoplasm, T-Lymphocytes, Cytotoxic, Tetradecanoylphorbol Acetate, Tumor Cells, Cultured, fas Receptor
Added May 27, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Cytokines and immunological monitoring.
Sosman JA, Sawhaney A
(1997) Cancer Chemother Biol Response Modif 17: 217-86
MeSH Terms: Animals, Cytokines, Granulocyte Colony-Stimulating Factor, Humans, Immunotherapy, Adoptive, Interferons, Interleukin-1, Interleukin-2, Interleukin-3, Lymphocytes, Tumor-Infiltrating, Neoplasms, Tumor Necrosis Factor-alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms