NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense.Li H, Han W, Polosukhin V, Yull FE, Segal BH, Xie CM, Blackwell TS
(2013)
Mediators Inflamm 2013: 503213
MeSH Terms: Acute Lung Injury, Animals, Bacterial Infections, Cells, Cultured, I-kappa B Kinase, Imidazoles, Ligation, Macrophages, Mice, NF-kappa B, Neutrophils, Phagocytosis, Quinoxalines, SepsisAdded March 25, 2014 1 Communities
2 Members
0 Resources
14 MeSH Terms
Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome.Ware LB, Koyama T, Zhao Z, Janz DR, Wickersham N, Bernard GR, May AK, Calfee CS, Matthay MA
(2013)
Crit Care 17: R253
MeSH Terms: Aged, Biomarkers, Case-Control Studies, Critical Care, Diagnosis, Differential, Female, Humans, Lung Injury, Male, Middle Aged, Respiratory Distress Syndrome, Retrospective Studies, SepsisAdded March 7, 2014 0 Communities
2 Members
0 Resources
13 MeSH Terms
0 Communities
1 Members
0 Resources
3 MeSH Terms
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.Fessel JP, Flynn CR, Robinson LJ, Penner NL, Gladson S, Kang CJ, Wasserman DH, Hemnes AR, West JD
(2013)
Am J Respir Cell Mol Biol 49: 778-87
MeSH Terms: Animals, Arterial Pressure, Bone Morphogenetic Protein Receptors, Type II, Cardiac Output, Cell Line, Tumor, Disease Models, Animal, Endothelial Cells, Familial Primary Pulmonary Hypertension, Humans, Hyperoxia, Hypertension, Pulmonary, Lung, Lung Injury, Mice, Mice, Transgenic, Mitochondria, Mitochondrial Membranes, Mutation, Oxidative Stress, Pulmonary Artery, Reactive Oxygen Species, Stress, Physiological, Ventricular Function, Right, Ventricular PressureAdded April 17, 2014 2 Communities
2 Members
0 Resources
24 MeSH Terms
NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity.Han W, Li H, Cai J, Gleaves LA, Polosukhin VV, Segal BH, Yull FE, Blackwell TS
(2013)
J Immunol 190: 4786-94
MeSH Terms: Animals, DNA-(Apurinic or Apyrimidinic Site) Lyase, Lipopolysaccharides, Lung, Lung Injury, Mice, NADPH Oxidases, NF-kappa B, Neutrophils, Oxidation-Reduction, Pneumonia, Reactive Oxygen SpeciesAdded March 7, 2014 1 Communities
2 Members
0 Resources
12 MeSH Terms
β-Catenin and CCNs in lung epithelial repair.Lawson WE, Blackwell TS
(2013)
Am J Physiol Lung Cell Mol Physiol 304: L579-81
MeSH Terms: Acute Lung Injury, Animals, CCN Intercellular Signaling Proteins, Cysteine-Rich Protein 61, Female, Humans, Proto-Oncogene Proteins, Respiratory Mucosa, Transendothelial and Transepithelial Migration, beta CateninAdded March 7, 2014 1 Communities
2 Members
0 Resources
10 MeSH Terms
β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2013)
Am J Respir Crit Care Med 187: 630-9
MeSH Terms: Animals, Bleomycin, Disease Models, Animal, Epithelium, In Situ Nick-End Labeling, Lung Injury, Mice, Mice, Transgenic, Pulmonary Alveoli, Pulmonary Fibrosis, Wound Healing, beta CateninAdded March 5, 2014 1 Communities
2 Members
0 Resources
12 MeSH Terms
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR, Segal BH
(2013)
J Immunol 190: 1714-24
MeSH Terms: Acute Lung Injury, Animals, Cell Line, Tumor, Disease Models, Animal, Human Umbilical Vein Endothelial Cells, Humans, Inflammation Mediators, Intubation, Intratracheal, Male, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, NADPH Oxidases, NF-E2-Related Factor 2, Neutrophil Infiltration, NeutrophilsAdded March 13, 2014 0 Communities
1 Members
0 Resources
17 MeSH Terms
0 Communities
1 Members
0 Resources
7 MeSH Terms
Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress.Bastarache JA, Sebag SC, Clune JK, Grove BS, Lawson WE, Janz DR, Roberts LJ, Dworski R, Mackman N, Ware LB
(2012)
Thorax 67: 1032-9
MeSH Terms: Acute Lung Injury, Analysis of Variance, Animals, Blotting, Western, Bronchoalveolar Lavage, Cytokines, Electrophoresis, Polyacrylamide Gel, Furans, Hemoglobins, Hemorrhage, Inflammation, Isoprostanes, Lipopolysaccharides, Mice, Mice, Knockout, Oxidative Stress, Pulmonary Alveoli, Real-Time Polymerase Chain Reaction, Statistics, Nonparametric, ThromboplastinAdded March 7, 2014 0 Communities
3 Members
0 Resources
20 MeSH Terms