Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 11 to 17 of 17

Publication Record

Connections

Phase I pharmacokinetic and pharmacodynamic study of 17-N-allylamino-17-demethoxygeldanamycin in pediatric patients with recurrent or refractory solid tumors: a pediatric oncology experimental therapeutics investigators consortium study.
Bagatell R, Gore L, Egorin MJ, Ho R, Heller G, Boucher N, Zuhowski EG, Whitlock JA, Hunger SP, Narendran A, Katzenstein HM, Arceci RJ, Boklan J, Herzog CE, Whitesell L, Ivy SP, Trippett TM
(2007) Clin Cancer Res 13: 1783-8
MeSH Terms: Adolescent, Adult, Antineoplastic Agents, Benzoquinones, Biomarkers, Tumor, Child, Child, Preschool, Female, Humans, Lactams, Macrocyclic, Male, Maximum Tolerated Dose, Neoplasms, Pediatrics, Recurrence, Treatment Failure
Added March 5, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
Heat shock protein 90 modulates endothelial nitric oxide synthase activity and vascular reactivity in the newborn piglet pulmonary circulation.
Aschner JL, Foster SL, Kaplowitz M, Zhang Y, Zeng H, Fike CD
(2007) Am J Physiol Lung Cell Mol Physiol 292: L1515-25
MeSH Terms: Adenosine Triphosphate, Animals, Animals, Newborn, Benzoquinones, Cells, Cultured, Cyclic GMP, Dicarbethoxydihydrocollidine, Endothelial Cells, Enzyme Inhibitors, HSP90 Heat-Shock Proteins, Lactams, Macrocyclic, Macrolides, Microcirculation, Nitric Oxide, Nitric Oxide Synthase Type III, Pulmonary Artery, Pulmonary Circulation, Superoxides, Swine, Vascular Resistance
Added May 20, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes.
Peng X, Guo X, Borkan SC, Bharti A, Kuramochi Y, Calderwood S, Sawyer DB
(2005) J Biol Chem 280: 13148-52
MeSH Terms: Adenosine Diphosphate, Adenosine Triphosphate, Animals, Benzoquinones, Cell Proliferation, Cells, Cultured, Dose-Response Relationship, Drug, Glycolysis, HSP90 Heat-Shock Proteins, Immunoprecipitation, Lactams, Macrocyclic, Ligands, Male, Muscle Cells, Myocytes, Cardiac, Oxygen Consumption, Phosphorylation, Protein Binding, Quinones, Rats, Rats, Sprague-Dawley, Receptor, ErbB-2, Receptors, Adrenergic, beta, Time Factors
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Herbimycin A inhibits angiogenic activity in endothelial cells and reduces neovascularization in a rat model of retinopathy of prematurity.
McCollum GW, Rajaratnam VS, Bullard LE, Yang R, Penn JS
(2004) Exp Eye Res 78: 987-95
MeSH Terms: Animals, Benzoquinones, Cell Division, Cells, Cultured, Disease Models, Animal, Endothelial Cells, Enzyme Inhibitors, Humans, Infant, Newborn, Lactams, Macrocyclic, Protein-Tyrosine Kinases, Quinones, Rats, Rats, Sprague-Dawley, Retinal Neovascularization, Retinal Vessels, Retinopathy of Prematurity, Rifabutin, Vascular Endothelial Growth Factor A
Added October 9, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase.
Dikalov S, Landmesser U, Harrison DG
(2002) J Biol Chem 277: 25480-5
MeSH Terms: Ascorbic Acid, Benzoquinones, Cells, Cultured, Electron Spin Resonance Spectroscopy, HSP90 Heat-Shock Proteins, Humans, Hydroxylamine, Lactams, Macrocyclic, Muscle, Smooth, Vascular, NADPH-Ferrihemoprotein Reductase, Nitric Oxide, Nitric Oxide Synthase, Nitric Oxide Synthase Type III, Oxidation-Reduction, Quinones, Superoxides
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Model of inhibition of the NPM-ALK kinase activity by herbimycin A.
Turturro F, Arnold MD, Frist AY, Pulford K
(2002) Clin Cancer Res 8: 240-5
MeSH Terms: Anaplastic Lymphoma Kinase, Apoptosis, Benzoquinones, Blotting, Western, Cell Cycle, Enzyme Inhibitors, Humans, Indoles, Lactams, Macrocyclic, Lymphoma, Large B-Cell, Diffuse, Oncogene Proteins, Fusion, Phosphorylation, Poly(ADP-ribose) Polymerases, Protein-Tyrosine Kinases, Quinones, Receptor Protein-Tyrosine Kinases, Rifabutin, Tumor Cells, Cultured
Added April 7, 2010
0 Communities
1 Members
0 Resources
18 MeSH Terms
p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells.
Aono S, Nakagawa S, Reynolds AB, Takeichi M
(1999) J Cell Biol 145: 551-62
MeSH Terms: Alkaloids, Benzoquinones, Binding Sites, Cadherins, Catenins, Cell Adhesion Molecules, Cell Aggregation, Cytoskeletal Proteins, DNA Primers, DNA, Complementary, Electrophoresis, Enzyme Inhibitors, Gene Expression Regulation, Neoplastic, Genistein, HT29 Cells, Humans, Kidney, Lactams, Macrocyclic, Membrane Glycoproteins, Mucin-1, Naphthalenes, Phosphoproteins, Quinones, Rifabutin, Staurosporine, Trans-Activators, Transfection, alpha Catenin, beta Catenin
Added March 5, 2014
1 Communities
1 Members
0 Resources
29 MeSH Terms