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Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal.
Lees-Green R, Gibbons SJ, Farrugia G, Sneyd J, Cheng LK
(2014) Am J Physiol Gastrointest Liver Physiol 306: G711-27
MeSH Terms: Animals, Anoctamin-1, Calcium, Chloride Channels, Computer Simulation, Gastrointestinal Motility, Interstitial Cells of Cajal, Mice, Models, Biological, Muscle Contraction, Muscle, Smooth
Added April 26, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
A biophysically based finite-state machine model for analyzing gastric experimental entrainment and pacing recordings.
Sathar S, Trew ML, Du P, O'Grady G, Cheng LK
(2014) Ann Biomed Eng 42: 858-70
MeSH Terms: Animals, Calcium, Interstitial Cells of Cajal, Models, Biological, Stomach, Swine
Added April 26, 2016
0 Communities
1 Members
0 Resources
6 MeSH Terms
A simplified biophysical cell model for gastric slow wave entrainment simulation.
Du P, Gao J, O'Grady G, Cheng LK
(2013) Annu Int Conf IEEE Eng Med Biol Soc 2013: 6547-50
MeSH Terms: Calcium, Gastrointestinal Motility, Humans, Interstitial Cells of Cajal, Ions, Membrane Potentials, Models, Biological, Stomach
Added April 26, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Cellular automaton model for simulating tissue-specific intestinal electrophysiological activity.
Gao J, Du P, O'Grady G, Archer R, Gibbons SJ, Farrugia G, Cheng LK
(2013) Annu Int Conf IEEE Eng Med Biol Soc 2013: 5537-40
MeSH Terms: Animals, Automation, Computer Simulation, Electrophysiological Phenomena, Interstitial Cells of Cajal, Intestines, Mice, Mice, Knockout, Models, Biological, Organ Specificity, Time Factors
Added April 26, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Are interstitial cells of Cajal involved in mechanical stress-induced gene expression and impairment of smooth muscle contractility in bowel obstruction?
Wu CC, Lin YM, Gao J, Winston JH, Cheng LK, Shi XZ
(2013) PLoS One 8: e76222
MeSH Terms: Animals, Blotting, Western, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Fluorescent Antibody Technique, Gene Expression Regulation, Interstitial Cells of Cajal, Intestinal Obstruction, Mice, Muscle Contraction, Muscle, Smooth, Nitrobenzenes, Real-Time Polymerase Chain Reaction, Sulfonamides
Added April 26, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Mapping and modeling gastrointestinal bioelectricity: from engineering bench to bedside.
Cheng LK, Du P, O'Grady G
(2013) Physiology (Bethesda) 28: 310-7
MeSH Terms: Animals, Computer Simulation, Gastrointestinal Motility, Humans, Interstitial Cells of Cajal, Intestines, Models, Biological, Myoelectric Complex, Migrating, Stomach, Translational Research, Biomedical
Added April 26, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms
Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties.
Gao J, Du P, O'Grady G, Archer R, Farrugia G, Gibbons SJ, Cheng LK
(2013) J R Soc Interface 10: 20130421
MeSH Terms: Animals, Anoctamin-1, Chloride Channels, Image Processing, Computer-Assisted, Interstitial Cells of Cajal, Mice, Mice, Knockout, Models, Biological, Receptors, Serotonin, 5-HT2
Added April 26, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Circumferential and functional re-entry of in vivo slow-wave activity in the porcine small intestine.
Angeli TR, O'Grady G, Du P, Paskaranandavadivel N, Pullan AJ, Bissett IP, Cheng LK
(2013) Neurogastroenterol Motil 25: e304-14
MeSH Terms: Animals, Electrophysiology, Interstitial Cells of Cajal, Intestine, Small, Myoelectric Complex, Migrating, Signal Processing, Computer-Assisted, Swine
Added April 26, 2016
0 Communities
1 Members
0 Resources
7 MeSH Terms
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility.
Du P, O'Grady G, Gao J, Sathar S, Cheng LK
(2013) Wiley Interdiscip Rev Syst Biol Med 5: 481-93
MeSH Terms: Algorithms, Humans, Hydrodynamics, Interstitial Cells of Cajal, Models, Biological, Myocytes, Smooth Muscle, Sodium Channels, Stomach
Added April 26, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Rapid high-amplitude circumferential slow wave propagation during normal gastric pacemaking and dysrhythmias.
O'Grady G, Du P, Paskaranandavadivel N, Angeli TR, Lammers WJ, Asirvatham SJ, Windsor JA, Farrugia G, Pullan AJ, Cheng LK
(2012) Neurogastroenterol Motil 24: e299-312
MeSH Terms: Animals, Electrophysiology, Female, Interstitial Cells of Cajal, Membrane Potentials, Models, Theoretical, Muscle, Smooth, Myoelectric Complex, Migrating, Stomach, Submucous Plexus, Swine
Added April 26, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms