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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 43

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A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins.
Fibriansah G, Tan JL, Smith SA, de Alwis R, Ng TS, Kostyuchenko VA, Jadi RS, Kukkaro P, de Silva AM, Crowe JE, Lok SM
(2015) Nat Commun 6: 6341
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Cell Membrane, Chlorocebus aethiops, Cryoelectron Microscopy, Dengue, Dengue Virus, Enzyme-Linked Immunosorbent Assay, Epitopes, Genotype, Humans, Immunoglobulin Fab Fragments, Membrane Proteins, Mice, Molecular Sequence Data, Neutralization Tests, Protein Binding, Protein Structure, Quaternary, Sequence Homology, Amino Acid, Serogroup, Vero Cells
Added January 26, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Brezski RJ, Kinder M, Grugan KD, Soring KL, Carton J, Greenplate AR, Petley T, Capaldi D, Brosnan K, Emmell E, Watson S, Jordan RE
(2014) MAbs 6: 1265-73
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Monoclonal, Murine-Derived, Antibody-Dependent Cell Cytotoxicity, Bacterial Proteins, Blood Platelets, Cell Line, Cell Line, Tumor, Cysteine Endopeptidases, Dogs, Enzyme-Linked Immunosorbent Assay, Epitopes, Humans, Immunoglobulin Fab Fragments, Immunoglobulin G, Matrix Metalloproteinase 3, Platelet Count, Proteolysis, Rats, Rituximab
Added April 22, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface.
Fibriansah G, Tan JL, Smith SA, de Alwis AR, Ng TS, Kostyuchenko VA, Ibarra KD, Wang J, Harris E, de Silva A, Crowe JE, Lok SM
(2014) EMBO Mol Med 6: 358-71
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Cell Line, Dengue, Dengue Virus, Epitopes, Humans, Immunoglobulin Fab Fragments, Mice, Molecular Dynamics Simulation, Molecular Sequence Data, Protein Structure, Tertiary, Viral Envelope Proteins, Virus Internalization
Added January 26, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Endovascular thrombolysis for pediatric cerebral sinus venous thrombosis with tissue plasminogen activator and abciximab.
Khan IS, Ladner TR, Satti KF, Ehtesham M, Jordan LC, Singer RJ
(2014) J Neurosurg Pediatr 13: 68-71
MeSH Terms: Abciximab, Adolescent, Antibodies, Monoclonal, Anticoagulants, Cerebral Infarction, Endovascular Procedures, Headache, Humans, Immunoglobulin Fab Fragments, Magnetic Resonance Imaging, Male, Parietal Lobe, Sinus Thrombosis, Intracranial, Thrombolytic Therapy, Tissue Plasminogen Activator, Treatment Outcome
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency.
Bates JT, Keefer CJ, Utley TJ, Correia BE, Schief WR, Crowe JE
(2013) J Immunol 190: 3732-9
MeSH Terms: Amino Acid Sequence, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antibody Affinity, Antibody Specificity, Humans, Immunoglobulin Fab Fragments, Immunoglobulin Variable Region, Kinetics, Models, Molecular, Molecular Docking Simulation, Mutation, Neutralization Tests, Protein Binding, Protein Conformation, Recombinant Proteins, Respiratory Syncytial Virus, Human, Viral Fusion Proteins
Added March 7, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin.
Xu R, Krause JC, McBride R, Paulson JC, Crowe JE, Wilson IA
(2013) Nat Struct Mol Biol 20: 363-70
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Antibodies, Neutralizing, Antibodies, Viral, Antigen-Antibody Complex, Binding Sites, Crystallography, X-Ray, Epitopes, Hemagglutinin Glycoproteins, Influenza Virus, Humans, Immunoglobulin Fab Fragments, Influenza A Virus, H2N2 Subtype, Molecular Sequence Data, Mutation, Protein Conformation, Tryptophan, Tyrosine
Added January 26, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE, Wilson IA
(2010) Science 328: 357-60
MeSH Terms: Age Factors, Amino Acid Sequence, Antibodies, Neutralizing, Antibodies, Viral, Antigenic Variation, Cross Reactions, Crystallography, X-Ray, Disease Outbreaks, Epitopes, Glycosylation, Hemagglutinin Glycoproteins, Influenza Virus, Hemagglutinins, Viral, Humans, Immunoglobulin Fab Fragments, Influenza A Virus, H1N1 Subtype, Influenza Vaccines, Influenza, Human, Models, Molecular, Molecular Sequence Data, Protein Conformation
Added August 6, 2012
0 Communities
1 Members
0 Resources
20 MeSH Terms
Functional maturation of the human antibody response to rotavirus.
Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE
(2008) J Immunol 180: 3980-9
MeSH Terms: Antibodies, Viral, Antigens, Viral, Binding Sites, Antibody, Capsid Proteins, Humans, Immunodominant Epitopes, Immunoglobulin D, Immunoglobulin Fab Fragments, Immunoglobulin Heavy Chains, Immunoglobulin Variable Region, Kinetics, Respiratory Syncytial Viruses, Rotavirus, Somatic Hypermutation, Immunoglobulin
Added August 6, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms
A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo.
Williams JV, Chen Z, Cseke G, Wright DW, Keefer CJ, Tollefson SJ, Hessell A, Podsiad A, Shepherd BE, Sanna PP, Burton DR, Crowe JE, Williamson RA
(2007) J Virol 81: 8315-24
MeSH Terms: Animals, Antibodies, Monoclonal, Cell Line, Epitopes, Humans, Immunoglobulin Fab Fragments, Infant, Metapneumovirus, Neutralization Tests, Paramyxoviridae Infections, Peptide Library, Rats, Recombinant Proteins, Sigmodontinae, Viral Fusion Proteins, Viral Load
Added August 6, 2012
0 Communities
1 Members
0 Resources
16 MeSH Terms
Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles.
Weitkamp JH, Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE
(2003) J Immunol Methods 275: 223-37
MeSH Terms: Adult, Antibodies, Monoclonal, Antibodies, Viral, Antigens, Viral, B-Lymphocytes, Base Sequence, Capsid Proteins, Cell Separation, DNA Primers, DNA, Recombinant, Gastroenteritis, Genes, Immunoglobulin, Genetic Vectors, Humans, Immunoglobulin Fab Fragments, Immunoglobulin Heavy Chains, Immunoglobulin Light Chains, Infant, Polymerase Chain Reaction, Recombinant Proteins, Rotavirus, Rotavirus Infections
Added February 27, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms