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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 31

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Evaluation of long-term transgene expression in piggyBac-modified human T lymphocytes.
Nakazawa Y, Saha S, Galvan DL, Huye L, Rollins L, Rooney CM, Wilson MH
(2013) J Immunother 36: 3-10
MeSH Terms: Antineoplastic Agents, Azacitidine, Cells, Cultured, Cytokines, DNA Transposable Elements, Gene Expression, Green Fluorescent Proteins, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Leukocytes, Mononuclear, Nerve Tissue Proteins, Receptors, Antigen, T-Cell, T-Lymphocytes, Transfection, Transgenes
Added August 22, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.
Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, Burstein E, Schmitz ML, Kracht M
(2013) Nucleic Acids Res 41: 90-109
MeSH Terms: Acetylation, Animals, Cell Line, Chemokine CXCL2, Down-Regulation, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Hydroxamic Acids, Interleukin-1, Interleukin-8, Mice, NF-kappa B, Phosphorylation, RNA Polymerase II, Signal Transduction, Transcription Factor RelA, Transcription, Genetic
Added March 26, 2014
2 Communities
1 Members
0 Resources
18 MeSH Terms
HDAC inhibitors in kidney development and disease.
Brilli LL, Swanhart LM, de Caestecker MP, Hukriede NA
(2013) Pediatr Nephrol 28: 1909-21
MeSH Terms: Animals, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Kidney, Kidney Diseases, Organogenesis, Treatment Outcome
Added November 21, 2013
2 Communities
1 Members
0 Resources
8 MeSH Terms
Smoking induces epithelial-to-mesenchymal transition in non-small cell lung cancer through HDAC-mediated downregulation of E-cadherin.
Nagathihalli NS, Massion PP, Gonzalez AL, Lu P, Datta PK
(2012) Mol Cancer Ther 11: 2362-72
MeSH Terms: Acetylation, Antigens, CD, Benzamides, Cadherins, Carcinoma, Non-Small-Cell Lung, Cell Movement, Down-Regulation, Epigenesis, Genetic, Epithelial-Mesenchymal Transition, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Lung Neoplasms, Lymphoid Enhancer-Binding Factor 1, Neoplasm Invasiveness, Promoter Regions, Genetic, Pyridines, Smoking, Snail Family Transcription Factors, Survival Analysis, Transcription Factors, Transcription, Genetic
Added June 14, 2013
0 Communities
2 Members
0 Resources
23 MeSH Terms
The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells.
Wilson AJ, Holson E, Wagner F, Zhang YL, Fass DM, Haggarty SJ, Bhaskara S, Hiebert SW, Schreiber SL, Khabele D
(2011) Cancer Biol Ther 12: 484-93
MeSH Terms: Antineoplastic Agents, Apoptosis, Caspase 3, Cell Line, Tumor, Cell Nucleus, Cell Survival, Cisplatin, DNA Damage, Drug Resistance, Neoplasm, Drug Screening Assays, Antitumor, Drug Synergism, Female, Histone Deacetylase Inhibitors, Histones, Humans, Microscopy, Fluorescence, Ovarian Neoplasms, Phosphorylation, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerases
Added March 5, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis.
Zhang F, Shi Y, Wang L, Sriram S
(2011) PLoS One 6: e16795
MeSH Terms: Adult, Apoptosis, Case-Control Studies, Dose-Response Relationship, Drug, Female, Gene Expression Regulation, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Hydroxamic Acids, Kinetics, Leukocytes, Mononuclear, Male, Middle Aged, Multiple Sclerosis, Oligonucleotide Array Sequence Analysis, T-Lymphocytes, Tumor Suppressor Protein p53, Young Adult
Added April 18, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists.
Mandawat A, Fiskus W, Buckley KM, Robbins K, Rao R, Balusu R, Navenot JM, Wang ZX, Ustun C, Chong DG, Atadja P, Fujii N, Peiper SC, Bhalla K
(2010) Blood 116: 5306-15
MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Drug Synergism, Heterocyclic Compounds, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Indoles, Leukemia, Myeloid, Acute, Panobinostat, Peptides, Cyclic, RNA, Messenger, Receptors, CXCR4, Signal Transduction, Tumor Cells, Cultured
Added April 1, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
The effects of the histone deacetylase inhibitor romidepsin (FK228) are enhanced by aspirin (ASA) in COX-1 positive ovarian cancer cells through augmentation of p21.
Son DS, Wilson AJ, Parl AK, Khabele D
(2010) Cancer Biol Ther 9: 928-35
MeSH Terms: Aspirin, Blotting, Western, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Cyclin-Dependent Kinase Inhibitor p21, Cyclooxygenase 1, Depsipeptides, Dose-Response Relationship, Drug, Drug Synergism, Female, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Humans, Ovarian Neoplasms, Proteasome Endopeptidase Complex, RNA Interference, Reverse Transcriptase Polymerase Chain Reaction
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability.
Krishnan M, Singh AB, Smith JJ, Sharma A, Chen X, Eschrich S, Yeatman TJ, Beauchamp RD, Dhawan P
(2010) Oncogene 29: 305-12
MeSH Terms: 3' Untranslated Regions, Butyrates, Cell Line, Tumor, Cell Movement, Claudin-1, Colonic Neoplasms, Gene Expression Regulation, Neoplastic, Histone Deacetylase 2, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Immunoblotting, Membrane Proteins, RNA Interference, RNA Stability, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Transcription, Genetic
Added June 14, 2013
1 Communities
2 Members
0 Resources
18 MeSH Terms
T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation.
Chang S, Collins PL, Aune TM
(2008) J Immunol 181: 8372-81
MeSH Terms: Acetylation, Animals, Cell Differentiation, Cell Proliferation, Cells, Cultured, Histone Acetyltransferases, Histone Deacetylase Inhibitors, Histone Deacetylases, Histones, Interferon-gamma, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Knockout, Protein Transport, Repressor Proteins, Sin3 Histone Deacetylase and Corepressor Complex, T-Box Domain Proteins, Th1 Cells
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms