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Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.
Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, Alizadeh AA
(2015) Proc Natl Acad Sci U S A 112: E1116-25
MeSH Terms: Antigen-Presenting Cells, CREB-Binding Protein, Chromatin, Flow Cytometry, Histocompatibility Antigens Class II, Humans, Lymphoma, Follicular, Mutation, Neoplastic Stem Cells, Polymerase Chain Reaction
Added April 15, 2015
1 Communities
1 Members
0 Resources
10 MeSH Terms
CD8αα⁺ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity.
Van Kaer L, Algood HMS, Singh K, Parekh VV, Greer MJ, Piazuelo MB, Weitkamp JH, Matta P, Chaturvedi R, Wilson KT, Olivares-Villagómez D
(2014) Immunity 41: 451-464
MeSH Terms: Animals, Antigen Presentation, CD8 Antigens, Citrobacter rodentium, Cytochalasin D, Enterocolitis, Necrotizing, Helicobacter pylori, Histocompatibility Antigens Class I, Humans, Immunity, Mucosal, Inhibitor of Differentiation Protein 2, Interleukin Receptor Common gamma Subunit, Interleukin-15, Interleukin-2, Interleukin-7, Intestinal Mucosa, Lymphocyte Activation, Lymphocytes, Mice, Mice, Inbred C57BL, Mice, Knockout, Phagocytosis
Added January 20, 2015
0 Communities
5 Members
0 Resources
22 MeSH Terms
Neonatal Fc receptor promotes immune complex-mediated glomerular disease.
Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB
(2014) J Am Soc Nephrol 25: 918-25
MeSH Terms: Albuminuria, Animals, Anti-Glomerular Basement Membrane Disease, Antigen-Antibody Complex, Autoantigens, Collagen Type IV, Glomerulonephritis, HEK293 Cells, Histocompatibility Antigens Class I, Humans, Immunoglobulin G, Male, Mice, Mice, Inbred C57BL, Receptors, Fc
Added December 2, 2016
1 Communities
1 Members
0 Resources
15 MeSH Terms
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.
Bartha I, Carlson JM, Brumme CJ, McLaren PJ, Brumme ZL, John M, Haas DW, Martinez-Picado J, Dalmau J, López-Galíndez C, Casado C, Rauch A, Günthard HF, Bernasconi E, Vernazza P, Klimkait T, Yerly S, O'Brien SJ, Listgarten J, Pfeifer N, Lippert C, Fusi N, Kutalik Z, Allen TM, Müller V, Harrigan PR, Heckerman D, Telenti A, Fellay J
(2013) Elife 2: e01123
MeSH Terms: Alleles, Genome, Human, Genome, Viral, Genome-Wide Association Study, HIV Infections, HIV-1, Histocompatibility Antigens Class I, Host-Pathogen Interactions, Humans, Polymorphism, Single Nucleotide, Viral Load
Added March 13, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides.
Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri N
(2013) J Immunol 191: 1547-55
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Antigen Presentation, CD8-Positive T-Lymphocytes, Cells, Cultured, Consensus Sequence, Cytotoxicity, Immunologic, Endoplasmic Reticulum, Epitopes, T-Lymphocyte, Female, H-2 Antigens, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class I, Leucyl Aminopeptidase, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Molecular Sequence Data, Peptide Fragments, Proteasome Endopeptidase Complex
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Discovering naturally processed antigenic determinants that confer protective T cell immunity.
Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S
(2013) J Clin Invest 123: 1976-87
MeSH Terms: Animals, Antigen Presentation, Antigens, CD8-Positive T-Lymphocytes, Epitopes, Epitopes, T-Lymphocyte, HeLa Cells, Histocompatibility Antigens Class I, Humans, Immunodominant Epitopes, Mass Spectrometry, Mice, Mice, Transgenic, Peptides, Phenotype, T-Lymphocytes, Vaccinia virus
Added March 20, 2014
1 Communities
5 Members
0 Resources
17 MeSH Terms
Identification of myeloid cell subsets in murine lungs using flow cytometry.
Zaynagetdinov R, Sherrill TP, Kendall PL, Segal BH, Weller KP, Tighe RM, Blackwell TS
(2013) Am J Respir Cell Mol Biol 49: 180-9
MeSH Terms: Animals, Bone Density Conservation Agents, Clodronic Acid, Dendritic Cells, Flow Cytometry, Histocompatibility Antigens Class II, Lung, Macrophage Activation, Macrophages, Alveolar, Mice, Mice, Transgenic, Monocytes
Added November 14, 2013
2 Communities
3 Members
0 Resources
12 MeSH Terms
Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses.
Spencer CT, Dragovic SM, Conant SB, Gray JJ, Zheng M, Samir P, Niu X, Moutaftsi M, Van Kaer L, Sette A, Link AJ, Joyce S
(2013) Eur J Immunol 43: 1162-72
MeSH Terms: Amino Acid Sequence, Animals, Antigen Presentation, Antigen-Presenting Cells, Antigens, Ly, Epitopes, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Leucyl Aminopeptidase, Membrane Proteins, Mice, Mice, Knockout, Molecular Sequence Data, Peptide Fragments, Proteomics, Sequence Analysis, Protein, T-Lymphocytes, Helper-Inducer, Tandem Mass Spectrometry
Added April 18, 2013
0 Communities
3 Members
0 Resources
18 MeSH Terms
A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.
Davies RW, Wells GA, Stewart AF, Erdmann J, Shah SH, Ferguson JF, Hall AS, Anand SS, Burnett MS, Epstein SE, Dandona S, Chen L, Nahrstaedt J, Loley C, König IR, Kraus WE, Granger CB, Engert JC, Hengstenberg C, Wichmann HE, Schreiber S, Tang WH, Ellis SG, Rader DJ, Hazen SL, Reilly MP, Samani NJ, Schunkert H, Roberts R, McPherson R
(2012) Circ Cardiovasc Genet 5: 217-25
MeSH Terms: Adult, Aged, Alleles, Coronary Artery Disease, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Histocompatibility Antigens Class I, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Risk Factors, Whites
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis.
Alli R, Nguyen P, Boyd K, Sundberg JP, Geiger TL
(2012) J Immunol 188: 477-86
MeSH Terms: Alopecia Areata, Animals, CD8-Positive T-Lymphocytes, Hair Follicle, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Humans, Interleukin-10, Interleukin-17, Interleukin-4, Lymphocyte Activation, Mice, Mice, Knockout, Rats, Receptors, Antigen, T-Cell, alpha-beta
Added March 20, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms